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Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications

  • US 6,302,874 B1
  • Filed: 07/13/1999
  • Issued: 10/16/2001
  • Est. Priority Date: 07/13/1998
  • Status: Expired due to Fees
First Claim
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1. A method for treating degenerative skin conditions in a subject in need thereof, said method comprising applying at least one electric pulse to the surface of a region of skin and applying thereto a composition comprising L-ascorbic acid, or a cosmetically/pharmaceutically acceptable salt, ester or other derivative thereof, said electric pulse having a voltage from about 25 volts to about 120 volts and sufficient duration to cause electroporation of said region of skin, thereby delivering an effective amount of the L-ascorbic acid or the derivative thereof through the stratum corneum of the region of skin so as to improve the condition of the region of skin without substantial pain or skin irritation.

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