Electrostimulator

• US 6,304,781 B1
• Filed: 10/30/1998
• Issued: 10/16/2001
• Est. Priority Date: 10/31/1997
• Status: Expired due to Fees

• Current Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Original Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Inventors: Busch, Ulrich, Bartels, Klaus
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US09/182,419
• Time in Patent Office: 1,082 Days
• Field of Search: 607/7, 607/8, 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3706 Pacemaker parameters stimulation threshold A61N1/371
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation

Abstract

Electrostimulator (2), comprising an interface for connecting a working electrode (2), as well as a pulse generator that is connected on the output side to the interface for transmitting electrical pulses to the working electrode (10), with a first measuring instrument (10) that is connected to the interface for measuring the electrical voltage present at the interface and/or the electrical current flowing over the interface, as well as an arithmetic unit, connected on the input side to the first measuring instrument, for computing an output signal reflecting the capacity of the working electrode in dependence on the current and/or voltage at the interface.

Claims

1. An electrostimulator comprising:

one heart-working electrode adapted to be implanted in tissue adjacent to a heart;

an output connection for connection to the one working electrode;

a test signal generator having an output connected to the output connection for generating one of a pulse-shaped and periodically changeable test signal and feeding the signal to the output connection for stimulating the heart;

a first measuring device having an input connected to the output connection for measuring at least one of an electrical voltage present at the output connection and a current flowing over the output connection; and

an evaluation device having an input connected at least indirectly to the first measuring device for generating an output signal that reflects the working electrode capacity in dependence on at least one of the current and voltage present at the output connection and for determining whether the heart has been stimulated.

2. The electrostimulator according to claim 1, wherein the test signal generator produces the test signal that has an amplitude considerably below an amplitude of a stimulation pulse required to generate electrical pulses.

3. The electrostimulator according to claim 1, further comprising a measuring electrode, wherein the first measuring device comprises a voltage measuring instrument switched parallel to the test signal generator and further comprising a galvanostatic automatic control circuit coupled to the test signal generator to keep a constant current flowing through the measuring electrode.

4. The electrostimulator according to claim 1, further comprising an impedance spectrogram;

and an inductance coupled to the output connection and cooperating with the working electrode to form an oscillating circuit, wherein the test signal generator comprises an oscillator and the evaluation device comprises means for determining the oscillating frequency of the one of the oscillating circuit or of the impedance spectrogram.

5. The electrostimulator according to claim 4, and further comprising a switching device linking the inductance to the output connection.

6. The electrostimulator according to claim 4, wherein the test signal generator comprises a tunable oscillator.

7. The electrostimulator according to claim 1, wherein the working electrode comprises an endocardially arranged pacemaker electrode and the electrostimulator comprises a pacemaker connectable to the pacemaker electrode.

8. The electrostimulator according to claim 7, wherein the test signal generator operable with a lower pulse amplitude for the measuring of signals is a stimulation pulse generator.

9. The electrostimulator according to claim 8, wherein the stimulation pulse generator has a pacemaker function and a pacemaker parameter;

and wherein the electrostimulator further comprises an input amplifier connected to the output connection for amplifying signals received from the pacemaker electrode;

a signal detector connected in series after the input amplifier for detecting a cardiac response in the signal and for generating a first control signal in reaction to a missing response following a stimulation pulse;

a control circuit having an input connected to the signal detector for performing a first control operation with respect to one of the pacemaker function and the pacemaker parameter upon the appearance of the first control signal, and performing a second control operation if the first control signal does not appear.

10. The electrostimulator according to claim 9, where in the evaluation device includes comparator unit for comparing the output signal that reflects the electrode capacity to a comparison value, which comparator unit generates a second control signal if the comparison value is exceeded, and wherein the control circuit has a control input connected to the output of the comparator unit for performing the first or second control operation only if the second control signal is present at the control input.

11. The electrostimulator according to claim 9, wherein the control circuit has an output connected with the stimulation pulse generator of the pacemaker and is adapted for increasing at least one of the amplitude and the duration of the stimulation pulses following the appearance of the first control signal and for reducing these if the first control signal does not appear.

12. The electrostimulator according to claim 9, further comprising a device for adapting a stimulation rate in reaction to the pacemaker electrode signal, and which permits or blocks a rate adaptation in dependence on at least one of the first and second control signal, and wherein said control circuit is connected to a control input of the device for adapting the stimulation rate.

13. The electrostimulator according to claim 9, and further comprising a comparison value memory for storing a comparison value and having an output coupled to the comparison unit.

14. The electrostimulator according to claim 13, wherein the comparison value memory is programmable.

15. The electrostimulator according to claim 13, wherein the comparison value memory stores a predetermined comparison value.

16. The electrostimulator according to claim 13, wherein the comparison value memory has an input coupled to the output of the evaluation device and stores a comparison value obtained during preceding evaluations by the evaluation device.

19. A method of using the electrostimulator according to claim 3, wherein the constant current flowing through the measuring electrode is pulse-shaped, said method comprising:

measuring and storing first, second and third potential values and the length of the constant-current pulse at the working electrode immediately before and after the start of the constant-current pulse and immediately before switching off the constant-current pulse;

determining a series resistance of the measuring electrode by dividing the potential difference from the first and the second potential values by the constant current value, and

determining a phase-limit capacity of the working electrode from the third and second potential values by forming a quotient of the product of pulse length and pulse value of the constant current and the potential difference.

20. The method according to claim 19, wherein the constant-current pulse consists of a double pulse with mutually inverse current direction for the two partial pulses, the method further including:

determining the potential differences, the pulse lengths, the series resistances and the phase-limit capacities of the measuring electrode separately for each current direction; and

subsequently determining the average values for the series resistance and the phase-limit capacity.

17. An electrostimulator comprising:

one heart-working electrode adapted to be implanted in tissue adjacent to a heart;

an output connection for connection to the one working electrode;

a test signal generator having an output connected to the output connection for generating one of a pulse-shaped and periodically changeable test signal and feeding the signal to the output connection for stimulating the heart;

a first measuring device includes a voltage measuring instrument parallel connected to the test signal generator and having an input connected to the output connection for measuring an electrical voltage present at the output connection;

a second measuring device comprising a current measuring instrument, connected in series with the test signal generator and the output connection, for measuring the current flowing over the output connection when the test signal is flowing through the connection; and

an evaluation device having an input coupled to the first and second measuring devices for generating an output signal that reflects the working electrode capacitance in dependence on at least one of the current and voltage present at the output connection to determine whether the heart has been stimulated.

18. The electrostimulator according to claim 17, further comprising an integrator connected in series after the current measuring instrument and having an output connected to the evaluation device for determining an electrical charge that is discharged during the test signal.