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Multispectral imaging and characterization of biological tissue

  • US 6,307,957 B1
  • Filed: 06/27/2000
  • Issued: 10/23/2001
  • Est. Priority Date: 02/28/1997
  • Status: Expired due to Fees
First Claim
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1. A method of characterizing the condition of a region of interest of biological tissue, wherein the absorption and scattering of light in different spectral bands by the region of interest is a function of the condition of the tissue, the method comprising:

  • illuminating a portion of the tissue including the region of interest by light in at least one spectral band;

    conveying an image of the region of interest through an optical system to an image receiver;

    imaging a portion of the tissue including the region of interest at the at least one spectral band with the light re-emitted by the portion of the tissue to generate at least one digital image comprising signals whose values are a function of the condition of the region of interest of the tissue; and

    providing the digital images to a processor, wherein the processor;

    segments the digital images by generating a segmentation mask defining the boundary of the region of interest from a digital image in any one of the at least one spectral bands;

    estimates at least one rotationally and translationally invariant statistical measure of coefficient distributions of the multiscale wavelet maxima representations of the digital image;

    characterizes the condition of the tissue based on the estimated values; and

    outputs the characterization of the condition of the tissue.

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