Method and system for verifying the integrity of normal sinus rhythm templates

• US 6,312,388 B1
• Filed: 03/12/1999
• Issued: 11/06/2001
• Est. Priority Date: 03/12/1999
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Marcovecchio, Alan F., Hsu, William
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/267,306
• Time in Patent Office: 970 Days
• Field of Search: 600/508, 600/509, 600/513, 600/519
• US Class Current: 600/508
• CPC Class Codes: A61B 5/35 by template matching

Abstract

A method and system for verifying the integrity of normal sinus rhythm (NSR) templates and updating the NSR template after selected time intervals. At selected time intervals after establishing a NSR template, cardiac complexes are sensed and values for one or more cardiac parameters are measured. The values of the cardiac parameters are compared to predetermined value ranges for NSR cardiac complexes. When the values of the cardiac parameters fall within the predetermined value ranges, values for the differences between the values of the cardiac parameters for the cardiac complexes and the values for the cardiac parameters of the NSR cardiac complexes are calculated. When the values of the differences are greater than one or more threshold values, the NSR template is updated as a function of the sensed cardiac complexes.

Claims

1. A method comprising:

sensing cardiac complexes;

measuring values for one or more cardiac parameters from each of the sensed cardiac complexes;

determining the sensed cardiac complexes are normal sinus rhythm (NSR) complexes based on the values of the one or more cardiac parameters for each of the sensed cardiac complexes;

calculating a NSR template as a function of the NSR complexes;

examining the NSR template after a selected time interval, where the NSR template is examined by;

measuring values for the one or more cardiac parameters from each sensed cardiac complex in a predetermined set of cardiac complexes;

comparing the values of the one or more cardiac parameters from each sensed cardiac complex in the predetermined set of cardiac complexes to one or more predetermined value ranges;

when the values of the one or more cardiac parameters are within the one or more predetermined value ranges, calculating values for cardiac signal parameter differences between the values of the one or more cardiac parameters from each sensed cardiac complex in the predetermined set of cardiac complexes and the values of the one or more cardiac parameters for the NSR complexes; and

when the values for the cardiac signal parameter differences are greater than one or more threshold values, updating the NSR template as a function of the predetermined set of cardiac complexes.

2. The method of claim 1, where examining the NSR template occurs at one or more selected time intervals after calculating the NSR template.

3. The method of claim 1, including calculating the one or more threshold values by the multiplication of a predetermined deviation percentage and each value of the one or more cardiac parameters for the NSR cardiac complexes used to calculate the NSR template.

4. The method of claim 1, including when the values of the cardiac signal parameter differences are less than or equal to the one or more threshold values, retaining the NSR template and the values of the one or more cardiac parameters for the NSR cardiac complexes used to calculate the NSR template.

5. The method of claim 1, including reinitiating the selected time interval after examining the NSR template.

6. The method of claim 1, where the predetermined set of cardiac complexes includes a programmable number of cardiac complexes in the range of 5 to 100 cardiac complexes.

7. A method comprising:

examining a NSR template after a selected time interval, wherein the NSR template is calculated from NSR complexes, the NSR complexes having values for NSR parameters, and wherein the NSR template is examined by;

sensing cardiac complexes;

measuring values of one or more cardiac parameters from each of the sensed cardiac complexes;

comparing the values of the one or more cardiac parameters to one or more predetermined value ranges;

when the values of the one or more cardiac parameters are within the one or more predetermined value ranges, calculating values for cardiac signal parameter differences between the values of the one or more cardiac parameters and the values for the NSR parameters;

comparing the values for the cardiac signal parameter differences to the threshold values;

when the values for the cardiac signal parameter differences are greater than threshold values, replacing the values of the NSR parameters with the values of the one or more cardiac parameters; and

recalculating the NSR template as a function of the cardiac complexes.

8. The method of claim 7, where examining the NSR template occurs at one or more selected time intervals after calculating the NSR template.

9. The method of claim 7, including calculating the one or more threshold values by the multiplication of a predetermined deviation percentage and each of the values for NSR parameters.

10. The method of claim 7, including when the values of the cardiac signal parameter differences are less than or equal to the one or more threshold values, retaining the NSR template and the NSR parameters.

11. The method of claim 7, including reinitiating the selected time interval after examining the NSR template.

12. The method of claim 7, including:

determining the sensed cardiac complexes are normal sinus rhythm (NSR) complexes based on the values of the one or more cardiac parameters for each of the sensed cardiac complexes; and

calculating the NSR template as a function of the NSR complexes.

13. The method of claim 12, including calculating the one or more threshold values by the multiplication of the predetermined deviation percentage and each value of the one or more cardiac parameters for the NSR cardiac complexes used to calculate the NSR template.

14. A system, comprising:

an endocardial lead including at least one defibrillation coil electrode and at least one pacing electrode; and

an implantable cardioverter defibrillator, where the endocardial lead is physically and electrically coupled to the implantable cardioverter defibrillator and where the implantable cardioverter defibrillator includes;

input circuitry electrically coupled to the at least one defibrillation coil electrode and the at least one pacing electrode to sense cardiac complexes including normal sinus rhythm (NSR) cardiac complexes;

a morphology analyzer circuit coupled to the input circuitry where the morphology analyzer circuit measures values of cardiac parameters from sensed NSR cardiac complexes;

a template generating circuit coupled to the morphology analyzer circuit to calculate a normal sinus rhythm (NSR) template as a function of sensed NSR cardiac complexes; and

a template comparison circuit coupled to the template generating circuit to compare the values of the cardiac parameters for sensed cardiac complexes to predetermined value ranges after a selected time interval has elapsed, wherein the template comparison circuit calculates values for cardiac signal parameter differences between the values of the cardiac parameters from each of the sensed NSR cardiac complexes and the values of the cardiac parameters for the sensed cardiac complexes when the values of the cardiac parameters for the sensed cardiac complexes are within the predetermined value ranges, and when the values of the cardiac signal parameter differences are greater than threshold values the template generating circuit recalculates the NSR template as a function of the sensed cardiac complexes.

15. The system of claim 14, where the implantable cardioverter defibrillator includes a microprocessor coupled to the input circuitry, the morphology analyzer circuit, the template generating circuit, and the template comparison circuit, wherein the microprocessor includes a timer for counting the selected time interval.

16. The system of claim 14, where the template comparison circuit calculates the threshold values by multiplying a predetermined deviation percentage and the values for the cardiac parameters of the sensed NSR cardiac complexes used to calculate the NSR template.

17. A method of examining a normal sinus rhythm (NSR) template, comprising:

sensing cardiac complexes, which include NSR complexes;

measuring values for one or more cardiac parameters from each cardiac complex in a predetermined set of the sensed cardiac complexes;

comparing the values of the one or more cardiac parameters from each cardiac complex in the predetermined set of cardiac complexes to one or more predetermined value ranges;

when the values of the one or more cardiac parameters are within the one or more predetermined value ranges, calculating values for cardiac signal parameter differences between the values of the one or more cardiac parameters from each cardiac complex in the predetermined set of cardiac complexes and the values of the one or more cardiac parameters for NSR complexes; and

when the values for the cardiac signal parameter differences are greater than one or more threshold values, updating the NSR template as a function of the predetermined set of cardiac complexes.

18. The method of claim 17, which includes measuring values for one or more cardiac parameters from each of the sensed cardiac complexes;

determining the sensed cardiac complexes are NSR complexes based on the values of the one or more cardiac parameters for each of the sensed cardiac complexes; and

calculating the NSR template as a function of the NSR complexes.

19. The method of claim 18, including calculating the one or more threshold values by the multiplication of a predetermined deviation percentage and each value of the one or more cardiac parameters for the NSR complexes used to calculate the NSR template.

20. The method of claim 18, including when the values of the cardiac signal parameter differences are less than or equal to the one or more threshold values, retaining the NSR template and the values of the one or more cardiac parameters for the NSR cardiac complexes used to calculate the NSR template.

21. The method of claim 18, where examining the NSR template occurs at one or more selected time intervals after calculating the NSR template.

22. The method of claim 21, including reinitiating the selected time interval after examining the NSR template.

23. The method of claim 17, where the predetermined set of cardiac complexes includes a programmable number of cardiac complexes in the range of 5 to 100 cardiac complexes.