8-[;(2-hydroxy-4-methoxy benzoyl) amino];-octanoic acid compositions for delivering active agents
First Claim
Patent Images
1. A composition comprising:
- (A) at least one active agent; and
(B) a compound having the following formula
or a salt thereof.
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Accused Products
Abstract
Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.
221 Citations
22 Claims
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1. A composition comprising:
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(A) at least one active agent; and
(B) a compound having the following formula
or a salt thereof.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
(A) a composition as defined in claim 1; and
(B) (a) an excipient (b) a diluent, (c) a disintegrant, (d) a lubricant, (e) a plasticizer, (f) a colorant, (g) a dosing vehicle, or (h) any combination thereof.
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12. A dosage unit form as defined in claim 11, wherein said active agent is selected from the group consisting of a biologically active agent, a chemically active agent, or a combination thereof.
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13. A dosage unit form as defined in claim 12, wherein said biologically active agent comprises at least one peptide, mucopolysaccharide, carbohydrate, or lipid.
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14. A dosage unit form as defined in claim 12, wherein said biologically active agent is selected from the group consisting of human growth hormone, bovine growth hormone, growth hormone-releasing hormone, an interferon, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, erythropoietin, atrial naturetic factor, an antigen, a monoclonal antibody, samatostatin, adrenocorticotropin, gonadotropin releasing hormone, oxytocin, vasopressin, cromolyn sodium, vancomycin, parathyroid hormone, desferrioxamine (DFO), or any combination thereof.
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15. A dosage unit form as defined in claim 14, wherein said biologically active agent comprises an interferon, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, oxytosin, vasopressin, vancomycin, DFO, parathyroid hormone, and combinations thereof.
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16. A dosage unit form as defined in claim 11, wherein said biologically active agent comprises recombinant human growth hormone.
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17. A dosage unit form as defined in claim 11, wherein said biologically active agent comprises heparin.
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18. A dosage unit form as defined in claim 11, wherein said biologically active agent comprises low molecular weight heparin.
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19. A dosage unit form as defined in claim 11, is in the form of a tablet, a capsule, or a liquid.
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20. A dosage unit form as defined in claim 19, wherein said dosing vehicle is selected from the group consisting of water, 1,2-propane diol, ethanol, or any combination thereof.
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21. A method for administering an active agent to an animal in need of said agent, said method comprising administering orally to said animal a composition as defined in claim 2.
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22. A composition as defined in claim 5, wherein said biologically active agent comprises parathyroid hormone.
Specification