Heart stimulator determining cardiac output, by measuring the systolic pressure, for controlling the stimulation

• US 6,314,323 B1
• Filed: 07/06/2000
• Issued: 11/06/2001
• Est. Priority Date: 01/09/1998
• Status: Expired due to Term

• Current Assignee: Pacesetter AB (Abbott Laboratories)
• Original Assignee: Pacesetter AB (Abbott Laboratories)
• Inventors: Ekwall, Christer
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/582,895
• Time in Patent Office: 488 Days
• Field of Search: 600/513, 600/519, 600/526, 607/9, 607/23, 607/24
• US Class Current: 607/23
• CPC Class Codes: A61N 1/36564 controlled by blood pressure

Abstract

A heart stimulator has a circuit for determining cardiac output and for producing a control signal corresponding to the determined cardiac output, and a controller for controlling cardiac stimulation dependent on the control signal. The circuit for determining cardiac output includes a pressure sensor which measures pressure in the right ventricle and which generates an electrical pressure signal corresponding to the measured pressure, and an integrator supplied with the pressure signal which integrates the pressure signal between a start time and stop time to produce an integration result corresponding to the cardiac output, which is used to form the control signal. The pressure signal is bandpass filtered during a systolic phase to identify opening of a valve at the right ventricle as the start time, and to identify closing of the valve as the stop time.

Claims

1. A heart stimulator comprising:

a circuit for determining cardiac output and for producing a control signal corresponding to said cardiac output;

a controller for controlling cardiac stimulation dependent on said control signal; and

said circuit including a pressure sensor adapted to sense pressure in a right ventricle and to generate an electrical pressure signal corresponding to the sensed pressure, an integrator supplied with said pressure signal which integrates said pressure signal between a start time and a stop time to produce an integration result, corresponding to said cardiac output, forming said control signal, and wherein said pressure signal is bandpass filtered during a systolic phase to identify opening of a valve at said right ventricle as said start time and closing of said valve as said stop time.

2. A heart stimulator as claimed in claim 1 wherein said circuit determines said cardiac output on a beat-to-beat basis.

3. A heart stimulator as claimed in claim 1 wherein said circuit determines said cardiac output as an average value over a plurality of heartbeats.

4. A heart stimulator as claimed in claim 1 further comprising a lead having an electrode tip for conducting stimulation pulses to heart tissue and for sensing electrical heart activity, said lead also carrying said pressure sensor.

5. A heart stimulator as claimed in claim 4 wherein said pressure sensor comprises a piezoelectric pressure sensor disposed behind said electrode tip.

6. A heart stimulator as claimed in claim 1 wherein said integrator determines, as a measure of said cardiac output, a magnitude in an area of a pressure versus time plane limited by a curve represented by said pressure signal as a function of time between said start time and said stop time, and a straight line proceeding between respective values of said pressure signal at said start time and said stop time.

7. A heart stimulator as claimed in claim 1 further comprising a sensor for determining a metabolic need of a patient and for generating a metabolic need signal corresponding said metabolic need, and a comparator for comparing said metabolic need signal with said integration result, to obtain a comparison result, said comparison result forming said control signal.

8. A heart stimulator as claimed in claim 7 wherein said metabolic need sensor comprises a flow sensor adapted to measure venous blood return to the heart.

9. A heart stimulator as claimed in claim 7 wherein said metabolic need sensor comprises a further pressure sensor adapted to detect end diastolic pressure.

10. A heart stimulator as claimed in claim 7 wherein said metabolic need sensor comprises an activity sensor.

11. A heart stimulator as claimed in claim 7 wherein said metabolic need sensor comprises a sensor adapted to measure a blood parameter selected from the group consisting of blood oxygen saturation, blood carbon dioxide saturation, blood pH and blood temperature.

12. A heart stimulator as claimed in claim 1 comprising a stimulation pulse emitter for administering said stimulation, said stimulation pulse emitter having a stimulation rate, a stimulation pulse amplitude, a pulse duration and a pulse shape associated therewith, and wherein said control signal operates said stimulation pulse generator to adjust at least one of said parameters.