Hernia mesh

• US 6,319,264 B1
• Filed: 04/03/1998
• Issued: 11/20/2001
• Est. Priority Date: 04/03/1998
• Status: Expired due to Term

• Current Assignee: Bionx Implants, Oy
• Original Assignee: Bionx Implants, Oy
• Inventors: Paasimaa, Senja, Antikainen, Teuvo, Törmälä, Pertti
• Primary Examiner(s): Chaudhuri, Olik
• Assistant Examiner(s): Trinh, Vikki Hoa B.
• Application Number:
  US09/054,672
• Time in Patent Office: 1,327 Days
• Field of Search: 606/151-200, 606/213, 606/110, 606/112, 606/111, 602/43, 602/44, 623/11, 604/304-308
• US Class Current: 606/151
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2250/003 differing in adsorbability or resorbability, i.e. in adsorption or resorption time
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: D04B 21/12 characterised by thread material
• CPC Class Codes: D10B 2509/08 Hernia repair mesh

Abstract

According to the present invention, a flexible, fibrous hernia mesh is provided, which is intended to be implanted to close hernia defects. The mesh has at least two functional components or layers: (1) a rapidly degradable first layer and (2) a more slowly degradable (with respect to the first layer) second layer. Using the fibrous mesh of this invention, the hernia defect can be closed so that a) the second layer supports the area until the scar tissue is strong enough (around 6 months), to prevent recurrent hernia formation, b) while the more rapid degradation of the first layer induces scar tissue formation due to inflammatory reaction, and c) the second layer isolates the first layer from the abdominal cavity, preventing tissue to tissue adhesion onto the intestines. The mesh is placed on the uncovered fascia area with its more rapidly absorbable side (the first layer) towards the fascia.

Claims

1. A hernia mesh for use in repairing a defect in an abdominal wall or cavity, said mesh comprising:

a first layer capable of being anchored on the abdominal wall next to the defect, wherein said first layer has a first degradation time and is made from a bioabsorbable polymer, copolymer, polymer blend or polymer composite, wherein said first layer is porous and has a pore size between about 50-1000 μ

m and

a second layer, wherein said second layer is configured such that it is fixed on the first layer and capable of being placed in contact with the abdominal wall or cavity wherein said second layer has a second degradation time that is longer than the first degradation time and the second layer is made from a bioabsorbable polymer, copolymer, polymer blend or polymer composite.

2. The hernia mesh as set forth in claim 1, wherein said first layer has a fibrous structure wherein the fibrous structure is made of a fabric selected from the group consisting of woven fabric, knitted fabric, mesh and non-woven felt, and wherein the fabric comprises filament or staple fibers.

3. The hernia mesh as set forth in claim 2, wherein said second layer has a fibrous structure wherein the fibrous structure is made of a fabric selected from the group consisting of woven fabric, knitted fabric, mesh and non-woven felt, and wherein the fabric comprises filament or staple fibers.

4. A mesh as set forth in claims 3, further comprising a third layer comprising a biodegradable film, said third layer being positioned between the first layer and the second layer.

5. A mesh as set forth in claims 4, wherein the mesh is planar like.

6. A mesh as set forth in claims 5, wherein the mesh is made of biodegradable fibers having fiber diameter of 1-300 μ

m.

7. The hernia mesh of claim 1 wherein the second layer is porous and has a pore size between about 0.1 to 2.0 mm.

8. The hernia mesh of claim 1 wherein the second layer is dense.

9. The hernia mesh of claim 1 wherein the mesh further comprises growth factors.

10. The hernia mesh of claim 1 wherein the mesh further comprises angiogenic growth factors.

11. The hernia mesh of claim 1 wherein the mesh further comprises cyclosprine.

12. The hernia mesh of claim 4 wherein the third layer is about 1-300 μ

m thick.

13. A hernia mesh for use in repairing a defect in an abdominal wall or cavity, said mesh comprising:

a first layer capable of being anchored on the abdominal wall next to the defect, wherein said first layer has a first degradation time and is made from bioabsorbable polymer, copolymer, polymer blend or polymer composite, wherein said first layer is porous and has a pore size between about 50-1000 μ

m; and

second layer, wherein said second layer is configured such that it is fixed on the first layer and capable of being placed in contact with the abdominal wall or cavity, wherein said second layer has a second degradation time that is longer than the first degradation time, said second layer is made from bioabsorbable polymer, copolymer, polymer blend or polymer composite, and said second layer being capable of isolating the first layer from the abdominal cavity thus preventing tissue adhesion.