Over-coated chewing gum formulations including tableted center
First Claim
1. A chewing gum comprising:
- a tableted gum center comprising a water soluble portion and a water insoluble portion; and
a coating comprising a medicament that surrounds the tableted gum center, the coating comprising at least 50% by weight of the chewing gum product.
5 Assignments
0 Petitions
Accused Products
Abstract
Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent. The medicament or agent is present within the coating that surrounds a tableted gum center (the water soluble portion and a water insoluble base portion). By chewing the gum, the medicament or agent is released from the product. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.
224 Citations
36 Claims
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1. A chewing gum comprising:
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a tableted gum center comprising a water soluble portion and a water insoluble portion; and
a coating comprising a medicament that surrounds the tableted gum center, the coating comprising at least 50% by weight of the chewing gum product. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9)
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2. The chewing gum of 1 wherein the medicament is selected from the group consisting of analgesics, muscle relaxants, antibiotics, antivirals, stimulants, antihistamines, decongestants, anti-inflammatories, antacids, psychotherapeutic agents, insulin, vitamins, minerals, and cardiovascular agents.
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10. A product including a medicament comprising:
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a tableted gum center comprising a water soluble portion and a water insoluble portion, the water insoluble portion comprising at least 30% by weight of the tableted gum center; and
a coating that at least substantially surrounds the tableted gum center and comprises a medicament and a high-intensity sweetener, the coating comprising at least 50% by weight of the product. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
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19. A chewing gum product including a medicament comprising:
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a uniform gum center comprising a water-soluble and a water-insoluble portion; and
a coating that substantially surrounds the uniform gum center and comprises a medicament, the coating comprising at least 50% by weight of the chewing gum product. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27)
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28. A product including a medicament comprising:
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a gum center having a controlled size and shape and comprising a water-soluble and a water-insoluble portion; and
a coating that substantially surrounds the gum center and comprises a medicament, the coating comprising at least 50% by weight of the product. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35, 36)
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Specification