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Repeat polymorphism in the frataxin gene and uses therefore

  • US 6,322,978 B1
  • Filed: 04/15/1999
  • Issued: 11/27/2001
  • Est. Priority Date: 04/20/1998
  • Status: Expired due to Fees
First Claim
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1. A method for determining whether a human subject is at risk for non-insulin dependent diabetes mellitus (NIDDM) comprising:

  • obtaining a biological sample from said subject; and

    detecting the presence or absence of an intermediate GAA repeat length polymorphism of 10 to 36 repeats in a frataxin gene in said biological sample, wherein the presence of an intermediate GAA repeat length polymorphism of 10 to 36 repeats in the frataxin gene indicates higher risk for NIDDM than does the absence of the polymorphism, thereby determining whether said subject is at risk for NIDDM.

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