Self-contained, transportable blood processsing device

• US 6,325,775 B1
• Filed: 09/03/1999
• Issued: 12/04/2001
• Est. Priority Date: 09/03/1999
• Status: Expired due to Term

• Current Assignee: Fenwal Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Baxter International Inc.
• Inventors: Thom, Sandra, Kendall, James W, Westberg, Tom
• Primary Examiner(s): Kim, John
• Assistant Examiner(s): SORKIN, DAVID L
• Application Number:
  US09/390,489
• Time in Patent Office: 823 Days
• Field of Search: 210/85, 210/90, 210/97, 210/102, 210/141, 210/143, 210/416.1, 210/782, 210/787, 210/739, 422/104, 604/6.02, 604/6.04, 604/6.1, 604/6.11
• US Class Current: 604/6.02
• CPC Class Codes: A61M 1/0236 with sampling means, e.g. sample bag or sampling port
• CPC Class Codes: A61M 1/30 Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/302 having a reservoir for withdrawn untreated blood
• CPC Class Codes: A61M 1/303 having a reservoir for treated blood to be returned
• CPC Class Codes: A61M 1/308 Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362264 the filter being a blood filter
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3633 Blood component filters, e.g. leukocyte filters
• CPC Class Codes: A61M 1/3693 using separation based on different densities of components, e.g. centrifuging
• CPC Class Codes: A61M 1/3696 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2209/06 Packaging for specific medical equipment
• CPC Class Codes: A61M 2209/084 Supporting bases, stands for equipment

Abstract

A blood processing device is self-contained within a case, which sized to enable hand transport. Self-contained in the case is a blood separation device, which, for example, can comprise a centrifuge. A controller is also self-contained in the case. The controller includes a control program for carrying out one or more blood processing procedures. A fluid processing system employs a centralized cassette containing preformed, fluid pressure actuated pump stations, preformed fluid flow paths, and preformed, fluid pressure actuated valves in the fluid flow paths. A fluid pressure actuator in the case holds the cassette and selectively applies fluid pressure force to the valves and pump stations in response to the control program. The control program thereby operates the cassette to convey blood to and from the blood separation device through the fluid processing system.

Claims

1. A blood processing system comprising

a universal fluid processing set including a blood processing chamber, a cassette containing preformed, fluid pressure actuated pump stations, preformed fluid flow paths, and preformed, fluid pressure actuated valves in the fluid flow paths, and tubing coupling the cassette to the blood processing chamber,

a processing apparatus including

a case sized to enable hand transport,

a blood separation centrifuge mounted in the case and configured to receive the blood processing chamber,

support elements mounted in the case to hold the tubing of the universal fluid processing set in communication with the blood separation centrifuge,

a fluid pressure actuator in the case to hold the cassette and to selectively apply fluid pressure force to the valves and pump stations to thereby convey blood to and from the blood separation centrifuge through the tubing of the universal fluid processing set to separate blood into red blood cells and plasma, and

a controller mounted in the case including a first selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a first blood separation procedure using the universal fluid processing set to collect red blood cells from a donor while returning plasma to the donor, the controller also having a second selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a second blood separation procedure using the universal fluid processing set to collect both plasma and red blood cells from a donor, and the controller including an input device allowing an operator to select execution of either the first or second control program.

2. A system according to claim 1

wherein the controller includes a third selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a first blood separation procedure using the universal fluid processing set to collect plasma from a donor while returning red blood cells to the donor, and

wherein the input device allows an operator to select execution of either the first or second or third control program.

5. A system according to claim 1 or 2 or 3 or 4

wherein the fluid pressure comprises positive and negative pneumatic pressure.

3. A blood processing system comprising

a universal fluid processing set including a blood processing chamber, a cassette containing preformed, fluid pressure actuated pump stations, preformed fluid flow paths, and preformed, fluid pressure actuated valves in the fluid flow paths, and tubing coupling the cassette to the blood processing chamber,

a processing apparatus including

a case sized to enable hand transport,

a blood separation centrifuge mounted in the case and configured to receive the blood processing chamber,

support elements mounted in the case to hold the tubing of the universal fluid processing set in communication with the blood separation centrifuge,

a fluid pressure actuator in the case to hold the cassette and to selectively apply fluid pressure force to the valves and pump stations to thereby convey blood to and from the blood separation centrifuge through the tubing of the universal fluid processing set, and

a controller mounted in the case including a first selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a first blood separation procedure using the universal fluid processing set to collect plasma from a donor while returning red blood cells to the donor, the controller also having a second selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a second blood separation procedure using the universal fluid processing set to collect both plasma and red blood cells from a donor, and the controller including an input device allowing an operator to select execution of either the first or second control program.

4. A blood processing system comprising

a universal fluid processing set including a blood processing chamber, a cassette containing preformed, fluid pressure actuated pump stations, preformed fluid flow paths, and preformed, fluid pressure actuated valves in the fluid flow paths, and tubing coupling the cassette to the blood processing chamber,

a processing apparatus including

a case sized to enable hand transport,

a blood separation centrifuge mounted in the case and configured to receive the blood processing chamber,

support elements mounted in the case to hold the tubing of the universal fluid processing set in communication with the blood separation centrifuge,

a fluid pressure actuator in the case to hold the cassette and to selectively apply fluid pressure force to the valves and pump stations to thereby convey blood to and from the blood separation centrifuge through the tubing of the universal fluid processing set, and

a controller mounted in the case including a first selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a first blood separation procedure using the universal fluid processing set to collect red blood cells from a donor while returning plasma to the donor, the controller also having a second selectable control program executable to direct the fluid pressure actuator to apply fluid pressure force to the valves and pump stations to perform a second blood separation procedure using the universal fluid processing set to collect plasma from a donor while returning red blood cells to the donor, and the controller including an input device allowing an operator to select execution of either the first or second control program.