Materials collection system and uses thereof

• US 6,325,806 B1
• Filed: 01/31/2000
• Issued: 12/04/2001
• Est. Priority Date: 10/30/1995
• Status: Expired due to Term

• Current Assignee: Biomedical Enterprises Incorporated (Johnson & Johnson)
• Original Assignee: Biomedical Enterprises Incorporated (Johnson & Johnson)
• Inventors: Fox, William Casey
• Primary Examiner(s): REIP, DAVID OWEN
• Application Number:
  US09/494,872
• Time in Patent Office: 673 Days
• Field of Search: 606/79-86, 606/53, 606/102, 606/96, 604/4, 604/187
• US Class Current: 606/80
• CPC Class Codes: A61B 10/0233 Pointed or sharp biopsy instruments
• CPC Class Codes: A61B 17/1635 for grafts, harvesting or transplants
• CPC Class Codes: A61B 17/1637 Hollow drills or saws producing a curved cut, e.g. cylindrical A61B10/025, A61B17/1695 take precedence
• CPC Class Codes: A61B 2010/0258 Marrow samples
• CPC Class Codes: A61B 2017/00969 used for transplantation
• CPC Class Codes: A61B 2090/033 Abutting means, stops, e.g. abutting on tissue or skin
• CPC Class Codes: A61B 2090/063 for measuring volume

Abstract

The present invention relates to instrumentation and uses thereof for collection of cuttings from cutting tools. Cuttings may be from precious metals, toxic or hazardous substances, or from living tissue such as bone. In a particular embodiment of collecting bone cuttings, the present invention includes instrumentation used with a drill bit so that bone cuttings (195) are aseptically collected in a collection chamber (110) for subsequent transplantation purposes. When in use, marrow and bone cuttings (195) are drawn into the flutes (170) of a drill bit (150), carried up the bore of the instrument tip (100) and collect in the collection chamber (110). The flutes of the drill bit (150) can be cleared of residual tissue through the use of a rotating flute wiper (160) that rotates with the drill bit (150) when drilling or when the drill bit (150) is withdrawn from the instrument. In this embodiment, use of the device allows collection of vital bone tissue for reconstruction of bone defects, fractures, or fixation of orthopedic or dental implants that contact bone.

Claims

1. An instrument for collection of cuttings, comprising:

a tip having a bore for fitting to a cutting tool having a flute, wherein when fitted with a cutting tool having a flute, the tip and the flute form an enclosed channel; and

a collection chamber attached to the tip for collecting and holding cuttings;

a cutting tool having a flute fitted through the bore of the tip and translatable in and out through the instrument;

wherein when in use, the instrument allows continuous unidirectional cutting tool rotation and cutting tool translation in and out through the instrument so as to channel, pull, or fling cuttings for accumulation in the collection chamber.

2. The instrument of claim 1 is further comprising a cap attachable to the collection chamber, the cap adapted for use with a cutting tool.

3. The instrument of claim 1 or 2 wherein the cutting tool is a concentrically oriented cutting tool.

4. The instrument of claim 3 wherein the cutting tool is selected from the group consisting of a drill bit, bur, grinder, rasp, reamer, milling cutter, fluted trocar, and a fluted hole saw.

5. The instrument of claim 3 wherein the cutting tool is a drill bit.

6. The instrument of claim 3 wherein the cutting tool is fitted with an adjustable stop.

7. The instrument of claim 3 further comprising means for rotating the cutting tool.

8. The instrument of claim 7 wherein the means for rotating the cutting tool is an external motor.

9. The instrument of claim 2 wherein the collection chamber further comprises an opening for connection to a vacuum line.

10. The instrument of claim 1 or 2 further comprising an attachment for processing cuttings.

11. A materials transplant system comprising:

the instrument of claim 1; and

means for moving cuttings to a site of implantation.

12. The materials transplant system of claim 11 wherein the system is sterile.

13. The materials transplant system of claim 11 wherein the materials are tissue cuttings and the system further comprises means for processing tissue cuttings.

14. The materials transplant system of claim 13 wherein means for processing tissue cuttings comprises an encapsulation nozzle.

15. The materials transplant system of claim 11 wherein the collection chamber further comprises an opening for connection to a vacuum line.

16. A method for aseptically transplanting skeletal tissue from a first site to a second site comprising

harvesting skeletal tissue from a first site using the materials transplant system of claim 12;

and

aseptically transplanting harvested tissue to a second site.

17. The method of claim 16 further comprising the step of processing harvested skeletal tissue before transplanting at the second site.

18. The method of claim 17 wherein the processing is washing, grinding, filtering, separating, acid addition, base addition, encapsulant addition, pharmaceutical addition, or growth factor addition.

19. The method of claim 16 wherein the first site and the second site are within one subject.

20. A method for collection of cuttings of bone, metal, a ceramic, or a polymer, comprising

assembling the instrument of claim 1;

and

harvesting cuttings of bone, metal, the ceramic, or the polymer into the collection chamber thereby, collecting the cuttings.

21. The method of claim 20 further comprising the step of flushing the collection chamber of the instrument with an inert gas for minimizing combustion hazard.

22. A method for collection of cuttings in a microgravity environment, comprising

assembling the instrument of claim 1;

and

harvesting cuttings in a microgravity environment into the collection chamber thereby, collecting the cuttings.

24. The instrument of claim 1, 2, or 23 wherein the tip further comprises a tooth.

25. The instrument of claim 1, 2, or 23 wherein the tip is a spherical tip.

26. The instrument of claim 1, 2, or 23 wherein the tip is a swivel tip.

27. The instrument of claim 1, 2, or 23 wherein the collection chamber further comprises a means for measuring volume.

28. The instrument of claim 27 wherein the collection chamber has a transparent or translucent wall and the means for measuring volume includes a volumetric marking on the wall.

29. The instrument of claim 1, 2, or 23 wherein the tip and the collection chamber are fabricated as one unit.

30. The instrument of claim 1, 2, or 23 wherein the collection chamber is positioned at an angle with respect to the tip.

23. An instrument for collection of cuttings, comprising:

a tip having a bore for fitting to a drill bit having a flute, wherein when fitted with a drill bit having a flute, the tip and the flute form an enclosed channel;

a collection chamber attached to the tip for collecting and holding cuttings; and

a drill bit having a flute fitted through the bore of the tip and translatable in and out through the instrument,

wherein when in use, the instrument allows continuous unidirectional drill bit rotation and drill bit translation in and out through the instrument so as to channel, pull, or fling cuttings for accumulation in the collection chamber.