Immunity testing device

• US 6,326,214 B1
• Filed: 03/03/1999
• Issued: 12/04/2001
• Est. Priority Date: 03/04/1998
• Status: Expired due to Fees

• Current Assignee: Wing-Yee Chan, Yung Hsiang Liu
• Original Assignee: Wing-Yee Chan, Yung Hsiang Liu
• Inventors: Chan, Wing-yee, Liu, Yung Hsiang
• Primary Examiner(s): NGUYEN, BAO THUY L
• Application Number:
  US09/261,753
• Time in Patent Office: 1,007 Days
• Field of Search: 422/58, 422/56, 422/61, 422/57, 422/60, 435/7.1, 435/7.93, 435/7.94, 435/287.7, 435/287.8, 435/287.9, 435/805, 435/810, 435/969, 435/970, 435/975, 436/518, 436/66, 436/530, 436/541, 436/810, 436/823
• US Class Current: 436/518
• CPC Class Codes: G01N 33/54366 Apparatus specially adapted for solid-phase testing
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10S 435/81 Packaged device or kit
• CPC Class Codes: Y10S 435/969 Multiple layering of reactants
• CPC Class Codes: Y10S 435/97 Test strip or test slide
• CPC Class Codes: Y10S 435/975 Kit
• CPC Class Codes: Y10S 436/81 Tube, bottle, or dipstick
• CPC Class Codes: Y10S 436/823 Immunogenic carrier or carrier per se

Abstract

An immunity testing device formed of a thin sheet of material folded to three portions, and the two end portions; named “front cover”0 and “back cover”; fold back to different sides of the center part; named base seat; to provide protection on both sides of the base seat. Two absorbent sheets bridged with a test paper are fixed on the side of base seat that'"'"'s facing the front cover. A hole is present at the position of the first absorbent sheet on base seat for specimen application. The front cover is disposed with observation cover plates at the position corresponding to the test paper and/or water-absorbing sheets for observation of test result as well as for preventing pollution before, and after use. The test paper is pre-embedded with antibodies/antigens to capture the corresponding antigens/antibodies in the test specimen as in Immunity method. The used testing device can be burned down to ensure environmental protection. The first water-absorbent sheet may be extended into part of the unfolding area under the observation cover plate for chemical testing in addition to immunological test method, therefor, dual methods testing is achieved.

Claims

1. An immunity testing device comprising:

a) a base having a base seat located between and integral with a front cover and a back cover, the base seat having first and second opposite facing surfaces;

b) first and second absorbent sheets located on the first surface of the base seat, the first and second absorbent sheets being spaced apart from each other;

c) a test paper located on the first surface of the base seat and in contact with the first and second absorbent sheets such that a liquid test sample applied to the first absorbent sheet will diffuse through the test paper to the second absorbing sheet;

d) a hole in the base seat covered by the first absorbent sheet such that the first absorbent sheet is accessible through the hole from the second surface of the base seat;

e) the front cover folded over and fixed to the first surface of the base seat so as to extend over the first and second absorbent sheets, the front cover having an observation area through which the test paper is exposed, the observation area being displaced from the hole;

f) an observation cover plate formed in the front cover so as to be movable between an open position, in which the test paper is exposed through the observation area, and a closed position in which the observation cover plate covers the test paper;

g) the back cover folded over onto the second surface of the base seat, so as to cover the hole; and

,

h) a releasable fastening device engaged by the back cover to releasably retain the back cover on the second surface of the base seat, the releasable fastening device enabling the back cover to be released and moved away from the second surface of the base seat to provide access to the hole whereby a liquid test sample may be applied to the first absorbent sheet.

2. The immunity testing device of claim 1 wherein the releasable fastening device comprises a tab formed integrally with the base seat which is releasably engagable by an edge of the back cover.

3. The immunity testing device of claim 1 wherein a portion of the first absorbent sheet is exposed through the observation area when the observation cover plate is in the open position.

4. The immunity testing device of claim 1 wherein the front cover is folded over and fixed to the first surface of the base seat by an adhesive.

5. The immunity testing device of claim 1 further comprising antibodies or antigens located in the first absorbent sheet.

6. The immunity testing device of claim 5 wherein the antibodies, or antigens located in the first absorbent sheet are labeled.

7. The immunity testing device of claim 6 wherein the labels are enzymes.

8. The immunity testing device of claim 6 wherein the label is a fluorescent material.

9. The immunity testing device of claim 6 wherein the labels are colored microparticles.