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Identification of molecular sequence signatures and methods involving the same

  • US 6,329,140 B1
  • Filed: 09/18/1997
  • Issued: 12/11/2001
  • Est. Priority Date: 09/19/1996
  • Status: Expired due to Term
First Claim
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1. A method of selecting clones for analysis comprising:

  • providing a support having a variety of clones associated therewith wherein said support is a high-density nucleic acid array with a density of at least four hundred different polynucleotides sequences per square centimeter;

    exposing said support to one or more polynucleotides under low, medium or high stringency conditions to permit at least some hybridization between said clones and said polynucleotides;

    identifying said clones that hybridize with said polynucleotides; and

    selecting at least one of said clones not identified in said identifying step for analysis.

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