Wound healing and treatment of fibrotic disorders
First Claim
Patent Images
1. A method of inhibiting fibrosis in a patient in need thereof comprising providing said patient with an amount of transforming growth factor consisting essentially of TGF-β
- 3 sufficient to effect said inhibition.
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Accused Products
Abstract
A healing composition containing at least one non-fibrotic growth factor in combination with a pharmaceutically acceptable carrier is disclosed. A method of preparation of the composition and method of treating a host, suffering from a wound or fibrotic condition, disease, disorder with the composition is also disclosed.
104 Citations
12 Claims
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1. A method of inhibiting fibrosis in a patient in need thereof comprising providing said patient with an amount of transforming growth factor consisting essentially of TGF-β
- 3 sufficient to effect said inhibition.
- View Dependent Claims (2, 3)
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4. A method of reducing scarring during healing of a wound in a patient in need thereof comprising providing at the site of said wound an amount of transforming growth factor consisting essentially of TGF-β
- 3 sufficient to effect said reduction in scarring.
- View Dependent Claims (5, 6)
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7. A method of inhibiting fibrosis in a patient in need thereof comprising providing said patient with an anti-fibrotic agent selected from the group consisting of and anti-TGF-β
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1, and anti-TGF-β
2 and an anti-PDGF antibody and an amount of transforming growth factor consisting essentially of TGF-β
3 sufficient to effect said inhibition. - View Dependent Claims (8, 9)
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1, and anti-TGF-β
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10. A method of reducing scarring during healing of a wound in a patient in need thereof comprising providing said patient with an anti-fibrotic agent selected from the group consisting of an anti-TGF-β
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1, an anti-TGFβ
2 and an anti-PDGF antibody and an amount of transforming growth factor consisting essentially of TGF-β
3 sufficient to effect said inhibition. - View Dependent Claims (11, 12)
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1, an anti-TGFβ
Specification