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Device for selective distribution of liquids

  • US 6,331,439 B1
  • Filed: 09/14/1998
  • Issued: 12/18/2001
  • Est. Priority Date: 06/07/1995
  • Status: Expired due to Term
First Claim
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1. A method of performing combinatorial processes, comprising the steps of:

  • providing an array having a top layer having reservoirs therein, a distribution plate adjacent to the top layer and a removable bottom plate having a plurality of reaction cells, wherein the distribution plate comprises at least one micropump, at least one microgate, at least one distribution reservoir, or at least one horizontal microchannel defined between the distribution plate and the top layer;

    loading the reservoirs of the top layer with a plurality of fluids;

    distributing fluids from the reservoirs through the distribution plate;

    applying said plurality of fluids to said plurality of reaction cells sequentially in accordance with a predefined sequence until a combinatorial process is completed; and

    removing the bottom plate of said array and analyzing the contents of the reaction cells.

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