Minute volume pacemakers that require only a single distal electrode

• US 6,334,071 B1
• Filed: 06/07/1999
• Issued: 12/25/2001
• Est. Priority Date: 06/07/1999
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Lu, Richard
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US09/326,939
• Time in Patent Office: 932 Days
• Field of Search: 607/18, 607/20, 607/24, 607/36, 600/547
• US Class Current: 607/20
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

In a rate-responsive pacemaker, the metabolic demand of the patient is determined by measuring the patient'"'"'s minute volume. Preferably, the pacemaker has a housing with a header, two external electrodes formed on the housing and/or the header, and at least one lead with a distal electrode extending from the header to the patient'"'"'s heart. The minute volume is determined by injecting a test current pulse between one of the external electrodes and the distal electrode, and detecting the resulting voltage between the distal electrode and the second external electrode.

Claims

1. An implantable cardiac stimulator comprising:

a housing having two external electrodes formed thereon;

a unipolar lead electrically isolated from the housing but extending therefrom and terminating at a distal electrode adapted for location in the heart of a patient;

a pulse generator disposed within the housing and generating stimulation pulses on the lead in response to trigger signals;

a metabolic demand detector that detects the metabolic demand of the patient and generates a metabolic demand parameter, the metabolic demand detector including a test pulse generator that generates a test pulse between one of the two external electrodes and the distal electrode, and a test sensor that senses voltage developed in response to the test pulse between the second of the two external electrodes and the distal electrode, the metabolic demand parameter being dependent on the sensed voltage; and

a control and timing circuit that generates the trigger signals at a rate determined by the magnitude of the metabolic demand parameter.

2. The stimulator of claim 1, wherein the distal electrode is adapted to be disposed in a cardiac chamber, and the pulse generator generates pacing pulses, the pacing pulses being extended to the cardiac chamber through the distal electrode.

3. The stimulator of claim 2, wherein the distal electrode is disposed in an atrium.

4. The stimulator of claim 2, wherein the distal electrode is disposed in a ventricle.

5. The stimulator of claim 1, further comprising a sense amplifier coupled to the distal electrode for sensing intrinsic activity in a patient'"'"'s heart, the sense amplifier generating a sense signal, and wherein the control and timing circuit responds to the sense signal as well as the magnitude of the metabolic demand parameter.

6. The stimulator of claim 1, wherein the external electrodes are dot electrodes formed on the housing.

7. The stimulator of claim 1, wherein the housing includes a housing body forming one of the external electrodes and a header attached to the housing body from which the lead extends.

8. The stimulator of claim 7, wherein the other of the external electrodes comprises a dot electrode.

9. The stimulator of claim 8, wherein the dot electrode is disposed on the header.

10. The stimulator claim 8, wherein the dot electrode is on the housing body but is electrically isolated therefrom.

11. The pacemaker of claim 1, wherein the housing comprises a metallic body and a header coupled to the housing body, with the lead extending from the header, wherein the first and second external electrodes are located on the header.

12. A rate-responsive pacemaker comprising:

a housing having first and second external electrodes formed thereon;

a unipolar lead electrically isolated from the housing but extending therefrom and having a distal electrode adapted to be disposed in a cardiac chamber;

a sensor amplifier that senses intrinsic activity in a patient'"'"'s heart and generates a corresponding sense signal;

a metabolic demand sensor in the housing for generating a current pulse between the distal electrode and the first housing external electrode and for sensing the voltage corresponding to the current pulse between the distal electrode and the second housing external electrode, the voltage being indicative of the metabolic demand of the patient;

a control and timing circuit responsive to the sense signal and the voltage for generating trigger signals; and

a pulse generator disposed in the housing for generating cardiac stimulation pulses in response to the trigger signals.

13. The pacemaker of claim 12, wherein the first and second external electrodes are dot electrodes formed on the housing.

14. The pacemaker of claim 12, wherein the housing comprises a metallic body that constitutes one of the first and second external electrodes, and a header coupled to the housing body, with the lead extending from the header.

15. The pacemaker of claim 12, wherein the other of the first and second external electrodes is on the header.

16. The pacemaker of claim 15, wherein the other of the first and second electrodes is a dot electrode.

17. The pacemaker of claim 14, wherein the other of the first and second electrodes is a dot electrode formed on the housing and electrically insulated from the metallic body.

18. The pacemaker of claim 12, wherein the housing comprises a metallic body and a header coupled to the housing body, with the lead extending from the header, wherein the first and second external electrodes are located on the header.

19. A method of providing rate-responsive stimulation to a patient'"'"'s heart using an implantable stimulator having a housing formed with two external electrodes thereon and a unipolar lead extending from the housing to the patient'"'"'s heart and including a distal electrode, comprising the steps of:

sensing an intrinsic activity within the heart and generating a corresponding sense signal;

determining the metabolic demand of the patient by generating a test pulse between one of the external electrodes and the distal electrode and detecting a response signal corresponding to the test pulse between the other of the external electrodes and the distal electrode;

generating a metabolic demand parameter corresponding to the response signal; and

generating pacing pulses responsive to the metabolic demand and the sense signal.

20. The method of claim 19, wherein the step of determining the metabolic demand of the patient includes generating a current test pulse and detecting a voltage constituting the metabolic response signal.