Implantable active medical device enslaved to at least one physiological parameter

• US 6,336,048 B1
• Filed: 11/24/1998
• Issued: 01/01/2002
• Est. Priority Date: 11/25/1997
• Status: Expired due to Term

• Current Assignee: Sorin CRM SAS (MicroPort Scientific Corp.)
• Original Assignee: Ela Medical S.A. (LivaNova Plc)
• Inventors: Bonnet, Jean-Luc
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US09/198,384
• Time in Patent Office: 1,134 Days
• Field of Search: 607/18, 607/19, 607/17, 607/20
• US Class Current: 607/19
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

An active implantable medical device, notably a cardiac pacemaker, enslaved to at least a physiological parameter which comprises at least one effort sensor (MV) having a plurality of determinable states, for measuring a primarily physiological parameter and delivering a signal which is a function of effort exerted by a patient bearing the device and at least one activity sensor (G) having a plurality of determinable states, for measuring a primarily physical parameter and delivering a signal which is indicative of the activity of the patient bearing the device. The determinable states of the respective sensors are determined and the relative sequence of successive changes in the state of the respective sensors are identified and analyzed periodically according to predetermined criteria. A command escape interval (IE_CONSIG) controlling the enslaved functioning of the device is determined from the analyzed states of the sensors. The command escape interval (IE_CONSIG) is then limited to predetermined values as appropriate.

Claims

1. An active implantable medical device having a control function enslaved to at least one physiological parameter comprising:

at least one effort sensor (MV) having a plurality of determinable states, the sensor measuring a primarily physiological parameter and delivering a signal which is a function of effort exerted by a patient bearing the device;

at least one activity sensor (G) having a plurality of determinable states, the sensor measuring a primarily physical parameter and delivering a signal indicative of the activity of the patient bearing the device;

means for determining the determinable states of the respective sensors;

means for identifying periodically a relative sequence of successive changes in the state of the respective sensors according to predetermined identification criteria;

means for analyzing periodically the relative sequence of successive changes in the state of the respective sensors according to predetermined analysis criteria;

means for determining a command escape interval (IE_CONSIG) controlling the control function of the device from the analyzed states of the sensors;

means for determining an escape interval of the activity sensor (IE_G); and

means for limiting the command escape interval (IE_CONSIG) as a function of the escape interval of the activity sensor (IE_G).

2. The device of claim 1 wherein the means for limiting the command escape interval (IE_CONSIG) include limitations which correspond to the subtraction of a predefined constant percentage of the escape interval of the activity sensor (IE_G).

3. The device of claim 1 wherein the means for limiting the command escape interval (IE_CONSIG) include two limitations, a lower limit (IE_LIMIT—

<sub>MV—

INF</sub>) and an upper limit (IE<sub>LIMIT—

MV—

SUP</sub>), which are applied to limit the command escape interval (IE_CONSIG).

4. The device of claim 3 wherein the means for analyzing further comprises means for determining whether the escape interval of the activity sensor (IE_G) has changed, and wherein the lower limit (IE_LIMIT—

<sub>MV—

INF</sub>) and the upper limit (IE<sub>LIMIT—

MV—

SUP</sub>) are redefined each time the means for analyzing determines that the escape interval of the activity sensor (IE_G) has changed.

5. The device of claim 1 further comprising means for calculating an enslavement frequency as a function of the analyzed states of the sensors.

6. The device of claim 5 wherein one of the plurality of determinable states comprises an effort state, the means for determining the determinable states further comprises means for determining when the effort sensor detects an effort state and when the activity sensor does not detect an effort state, and the means for limiting the command escape interval (IE_CONSIG) further comprises means for limiting the enslavement frequency when the effort sensor (MV) detects an effort not detected by the activity sensor (G).

7. A method for controlling an active implantable medical device having a control function enslaved to at least one physiological parameter comprising the steps of:

measuring a primarily physiological parameter and delivering a signal which is a function of effort exerted by a patient bearing the device;

measuring a primarily physical parameter and delivering a signal indicative of the activity of the patient bearing the device;

determining determinable states of the respective measurements;

identifying periodically a relative sequence of successive changes in the respective states according to predetermined identification criteria;

analyzing periodically the relative sequence of successive changes in the respective states according to predetermined analysis criteria;

determining a command escape interval (IE_CONSIG) controlling the control function of the device from the analyzed states;

determining an escape interval of the activity sensor (IE_G); and

limiting the command escape interval (IE_CONSIG) to predetermined values as a function of the escape interval of the activity sensor (IE_G).

8. The method of claim 7 wherein the command escape interval (IE_CONSIG ) is limited to predetermined values which correspond to the subtraction of a predefined constant percentage of the escape interval of the activity sensor (IE_G).

9. The method of claim 7 further comprising providing a lower limit (IE_LIMIT—

<sub>MV—

INF</sub>) and an upper limit (IE<sub>LIMIT—

MV—

SUP</sub>) and limiting the command escape interval (IE_CONSIG) by said upper and lower limits.

10. The method of claim 9 wherein analyzing the relative sequence of successive states further comprises determining that the escape interval of the activity sensor (IE_G) is modified and in response thereto redefining the upper and lower limits.

11. The method of claim 7 wherein the control function is an enslavement frequency, measuring the primarily physiological parameter further comprises providing an effort sensor to obtain said signal, and the step of limiting the command escape interval (IE_CONSIG) also includes limiting the enslavement frequency when the effort sensor (MV) detects an effort not detected by the activity sensor (G).

12. An active implantable medical device programmed to perform the method of claim 7.

13. An active implantable medical device having a control function enslaved to at least one physiological parameter comprising:

at least one effort sensor (MV) having a plurality of determinable states, the sensor measuring a primarily physiological parameter and delivering a signal which is a function of effort exerted by a patient bearing the device;

at least one activity sensor (G) having a plurality of determinable states, the sensor measuring a primarily physical parameter and delivering a signal indicative of the activity of the patient bearing the device;

means for determining the determinable states of the respective sensors;

means for identifying periodically a relative sequence of successive changes in the state of the respective sensors according to predetermined identification criteria;

means for analyzing periodically the relative sequence of successive changes in the state of the respective sensors according to predetermined analysis criteria;

means for determining a command escape interval (IE_CONSIG) controlling the control function of the device from the analyzed states of the sensors; and

means for limiting the command escape interval (IE_CONSIG) as a function of an escape interval of the activity sensor (IE_G);

14. A method for controlling an active implantable medical device having a control function enslaved to at least one physiological parameter comprising the steps of:

measuring a primarily physiological parameter and delivering a signal which is a function of effort exerted by a patient bearing the device;

measuring a primarily physical parameter and delivering a signal indicative of the activity of the patient bearing the device;

determining determinable states of the respective measurements;

identifying periodically a relative sequence of successive changes in the respective states according to predetermined identification criteria;

analyzing periodically the relative sequence of successive changes in the respective states according to predetermined analysis criteria;

determining a command escape interval (IE_CONSIG) controlling the control function of the device from the analyzed states; and

limiting the command escape interval (IE_CONSIG) to predetermined values as a function of an escape interval of the activity sensor (IE_G);

wherein one of the determinable states comprises a rest state and limiting the command escape interval (IE_CONSIG) is performed by applying the limitation of the command escape interval (IE_CONSIG) only where the physiological parameter is in a state other than the rest state.