Analgesic regimen
First Claim
Patent Images
1. A regimen for the treatment of pain which comprises administering to one in need thereof about 25 mg of tramadol on days 1-3;
- about 50 mg of tramadol on days 4-6;
about 75 mg of tramadol on days 7-9;
about 100 mg of tramadol on days 10-12;
about 150 mg of tramadol on days 13-15; and
about 200 mg of tramadol on days 16-28 and thereafter, in the form of a pharmaceutical composition containing tramadol as the active ingredient;
whereby discontinuations due to adverse side effects are reduced.
1 Assignment
0 Petitions
Accused Products
Abstract
A regimen for the administration of tramadol for the treatment of analgesia is described. The regimen involves a slower initial titration rate of tramadol which results in a significantly lower percentage of discontinuations of therapy due to a lower incidence and severity of side effects.
-
Citations
4 Claims
-
1. A regimen for the treatment of pain which comprises administering to one in need thereof about 25 mg of tramadol on days 1-3;
- about 50 mg of tramadol on days 4-6;
about 75 mg of tramadol on days 7-9;
about 100 mg of tramadol on days 10-12;
about 150 mg of tramadol on days 13-15; and
about 200 mg of tramadol on days 16-28 and thereafter, in the form of a pharmaceutical composition containing tramadol as the active ingredient;
whereby discontinuations due to adverse side effects are reduced. - View Dependent Claims (2, 3, 4)
- about 50 mg of tramadol on days 4-6;
Specification
-
- Resources
Litigation Campaign Assessment
Thank you for your request. You will receive a custom alert email when the Litigation Campaign Assessment is available.
×
-
Current AssigneeOrtho-McNeil Pharmaceutical Incorporated (Johnson & Johnson)
-
Original AssigneeOrtho-McNeil Pharmaceutical Incorporated (Johnson & Johnson)
-
InventorsOlson, William, Kamin, Marc
-
Primary Examiner(s)Rose, Shep K.
-
Application NumberUS09/415,753Time in Patent Office826 DaysField of Search514/646US Class Current514/646CPC Class CodesA61K 31/135 having aromatic rings , e.g...
