Method of controlling the stimulation amplitude of a cardiologic implant

• US 6,339,724 B1
• Filed: 06/26/2000
• Issued: 01/15/2002
• Est. Priority Date: 06/24/1999
• Status: Expired due to Fees

• Current Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Original Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Inventors: Thong, Tran
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/604,294
• Time in Patent Office: 568 Days
• Field of Search: 607/28, 607/8, 607/27
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

The invention is directed to a method of controlling the stimulation amplitude of a cardiologic implant which includes

a stimulation impedance during delivery of left chamber stimulation pulses in the form of a measured value representative of the delivered stimulation pulse as a criterion for capture; determining and storing a comparative simulation impedance value representative of the stimulation; detecting an amplitude threshold for capture by determination of a significant change in the detected stimulation impedance as compared to the stored comparative stimulation impedance value; and then adjusting the stimulation amplitude on the basis of the detected amplitude threshold.

Claims

1. A method of controlling a stimulation amplitude of a cardio-logic implant, which performs right and left chamber stimulation of a heart, using a left chamber stimulation electrode (14) in a coronary vein (13), comprising the following steps:

detecting a stimulation impedance during delivery of left chamber stimulation pulses in the form of a measured value representative of the delivered stimulation pulse as a criterion for capture;

determining and storing a comparative stimulation impedance value representative of a stimulation;

detecting an amplitude threshold for capture by determining a significant change in the detected stimulation impedance as compared to the stored comparative stimulation impedance value; and

adjusting the stimulation amplitude on the basis of the detected amplitude threshold.

2. A method according to claim 1, further comprising the steps of detecting the comparative impedance value continuously as an individual or average value over several stimulation pulses and then updating and storing said comparative impedance value.

3. A method according to claim 1, further comprising the step of detecting the amplitude threshold on the basis of a significant reduction of the stimulation impedance as compared to the comparative impedance value due to a loss of capture.

4. A method according to claim 1, further comprising the step of actively detecting the amplitude threshold by successively raising the amplitude of the stimulation pulses until capture is recognized by detecting a significant increase of the stimulation impedance as compared to the comparative impedance value.

5. A method according to claim 4, comprising the step of regularly repeating amplitude threshold detection for the amplitude threshold to be updated continuously.

6. A method according to claim 1, wherein the stimulation amplitude is set to overshoot the amplitude threshold by a buffer difference.

7. A method according to claim 1, wherein after non-capture has been detected, the stimulation amplitude for an ensuing pulse is set to a maximum and then reduced successively until a failure of capture defines the amplitude threshold.

8. A method according to claim 1, wherein after recognizing non-capture, the stimulation amplitude is set to a maximum for at least one pulse.

12. A method according to claim 1, wherein for determination of the measured impedance value which is representative of the delivered stimulation pulse, a stimulation current is measured at a defined instant after a start of the pulse and the impedance is calculated from said measured stimulation current and a stimulation voltage adjusted at the implant by Ohm'"'"'s Law.

9. A method of controlling a stimulation amplitude of a cardiologic implant which performs right and left chamber stimulation of a heart, using a tripolar stimulation arrangement comprising a left chamber stimulation electrode (14) in a coronary vein (13), a right chamber simulation electrode (9) in an associated right cardiac chamber (3) and a counter electrode (10), comprising the following steps:

detecting a stimulation impedance during delivery of left chamber stimulation pulses in form of a measured value representative of the delivered stimulation pulse as a criterion for capture;

determining and storing a comparative stimulation impedance value representative of stimulation;

detecting an amplitude threshold for capture by determining a significant chance in the detected stimulation impedance as compared to the stored comparative stimulation impedance value; and

adjusting the stimulation amplitude on the basis of detected amplitude threshold, wherein during the detection of the amplitude threshold, the stimulation impedance is monitored for an occurrence of a significant impedance increase upon transition from right chamber rapture to both left and right chamber capture and wherein the stimulation amplitude is adjusted to an amplitude value found upon the transition.

10. A method according to claim 9, wherein the amplitude value is not raised upon detection of a failure of left chamber capture.

13. A method according to claim 9, comprising the step of active detection of the amplitude threshold by successively raising the amplitude of the stimulation pulses until capture is recognized by detection of a significant increase of the stimulation impedance as compared to the comparative impedance value.

14. A method according to claim 9, wherein the stimulation amplitude is set to overshoot the amplitude threshold by d buffer difference.

15. A method according to claim 9, wherein alter non-capture has been detected, the stimulation amplitude for an ensuing pulse is set to a maximum and then reduced successively until a failure of capture defines the amplitude threshold.

16. A method according to claim 9, wherein after recognition of non-capture, the stimulation amplitude is set to a maximum for at least one pulse.

11. A method of controlling a stimulation amplitude of a cardiologic implant, which performs right and left chamber stimulation of a heart, using a left chamber stimulation of a heart, using a left chamber stimulation electrode (14) i a coronary vein (13) and a counter electrode (10), in a right chamber (3) comprising the following steps:

detecting a stimulation impedance during delivery of left chamber stimulation pulses in form of a measured value representative of the delivered stimulation pulse as a criterion for capture;

determining and storing a comparative stimulation impedance value representative of stimulation;

detecting an amplitude threshold for capture by determining a significant change in the detected stimulation impedance as compared to the stored comparative stimulation impedance value; and

adjusting the stimulation amplitude on the basis the detected amplitude threshold, wherein as a measured impedance value which is representative of the delivered stimulation pulse, an impedance average is detected, which is integrated or averaged by current and voltage being continuously recorded and evaluated over the pulse.

17. A method according to claim 11, comprising the step of active detection of the amplitude threshold by successively raising the amplitude of the stimulation pulses until capture is recognized by detection of a significant increase of the stimulation impedance as compared to the comparative impedance value.

18. A method according to claim 11, wherein the stimulation amplitude is set to overshoot the amplitude threshold by a buffer difference.

19. A method according to claim 11, wherein after non-capture has been detected, the stimulation amplitude for an ensuing pulse is set to a maximum and then reduced successively until a failure of capture defines the amplitude threshold.

20. A method according to claim 11 wherein after recognition of non-capture, the stimulation amplitude is set to a maximum for at least one pulse.