Polymer arrays
First Claim
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1. An array of polymers, the array comprising:
- a planar solid support; and
a plurality of different polymers attached to a surface of the planar solid support at a density exceeding 400 different polymers/cm2, wherein each of the different polymers is attached to the surface of the planar solid support in a different known location and, it is known which polymer occupies which known location.
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Abstract
A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
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Citations
19 Claims
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1. An array of polymers, the array comprising:
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a planar solid support; and
a plurality of different polymers attached to a surface of the planar solid support at a density exceeding 400 different polymers/cm2, wherein each of the different polymers is attached to the surface of the planar solid support in a different known location and, it is known which polymer occupies which known location. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification