Catheter for uniform delivery of medication

• US 6,350,253 B1
• Filed: 07/19/1999
• Issued: 02/26/2002
• Est. Priority Date: 07/19/1999
• Status: Expired due to Term

• Current Assignee: Avent Incorporated (Avanos Medical, Inc.)
• Original Assignee: I-Flow Corporation (Kimberly-Clark Corporation)
• Inventors: Deniega, Jose Castillo, Massengale, Roger, Rake, Kenneth W.
• Primary Examiner(s): Nguyen, Anhtuan T
• Assistant Examiner(s): Lam, Ann Y.
• Application Number:
  US09/363,228
• Time in Patent Office: 953 Days
• Field of Search: 604/264, 604/93.01, 604/164.01, 604/164.08, 604/164.09, 604/164.13, 604/167-1-1, 604/256, 604/27
• US Class Current: 604/164.02
• CPC Class Codes: A61M 2025/0037 characterized by lumina being arranged side-by-side
• CPC Class Codes: A61M 2025/0039 characterized by lumina being arranged coaxially
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/0073 Tip designed for influencing the flow or the flow velocity of the fluid, e.g. inserts for twisted or vortex flow general flow characteristics A61M2206/10
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0023 by the form of the lumen, e.g. cross-section, variable diameter
• CPC Class Codes: A61M 25/0043 characterised by structural features
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/0069 Tip not integral with tube
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0074 Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable

Abstract

The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with some embodiments, the catheter includes an elongated tubular member made of a porous membrane. The porous membrane is configured so that a fluid introduced into an open end of the tubular member will flow through side walls of the tubular member at a substantially uniform rate along a length of the tubular member. In accordance with other embodiments, the catheter includes an elongated “weeping” tubular coil spring attached to an end of, or enclosed within, a tube. Fluid within the spring and greater than or equal to a threshold pressure advantageously flows radially outward between the spring coils. Advantageously, the fluid is dispensed substantially uniformly throughout a length of the spring. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region.

Claims

1. A catheter for the delivery of fluid throughout an anatomical region, comprising:

a tube;

a tubular coil spring having a proximal end attached to a distal end of said tube; and

a stop closing a distal end of said spring;

said tube and said spring each defining a portion of a central lumen, said spring having adjacent coils in contact with one another when said spring is in a relaxed state, so that fluid within said spring and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils.

2. The catheter of claim 1, wherein said spring is configured so that the fluid between the coils is dispensed substantially uniformly throughout the length and circumference of a portion of said spring.

3. A method of delivering a fluid to an anatomical region, comprising the steps of:

introducing a fluid into an open proximal end of a tube;

allowing said fluid to flow into a tubular coil spring within an anatomical region and having a proximal end attached to a distal end of said tube so that said tube and spring each form a portion of a lumen, said spring having a stop closing a distal end of said spring, said spring having adjacent coils in contact with one another when said spring is in a relaxed state, so that said fluid within said spring and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils; and

bringing the fluid inside of said spring to a pressure greater than or equal to said threshold dispensation pressure;

wherein said fluid exits said lumen by flowing radially between said coils.

4. A method of manufacturing a catheter for the delivery of fluid throughout an anatomical region, comprising the steps of:

providing a tube;

attaching a proximal end of a tubular coil spring to a distal end of said tube so that said tube and said spring each define a portion of a central lumen, said spring having adjacent coils in contact with one another when said spring is in a relaxed state, so that fluid within said spring and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils; and

attaching a stop to the distal end of said spring.

5. A catheter for the delivery of fluid throughout an anatomical region, comprising:

a distally closed tube, a length of said tube defining an infusion section of said tube, said infusion section having a plurality of exit holes in a side wall of said tube; and

a tubular coil spring concentrically enclosed within said infusion section so that a lumen is defined within said tube and said spring;

said spring having adjacent coils in contact with one another so that fluid within said lumen and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils and through said exit holes.

6. The catheter of claim 5, wherein said spring is configured so that the fluid between the coils is dispensed substantially uniformly throughout the length and circumference of a portion of said spring and thereafter flows through substantially all of said exit holes.

7. The catheter of claim 6, wherein said exit holes are substantially equal in size so that the fluid flows through said exit holes at a substantially equal rate.

8. The catheter of claim 5, wherein said spring and said tube are in contact along a substantial length of said spring.

9. A method of delivering a fluid throughout an anatomical region, comprising the steps of:

inserting an infusion section of a tube into an anatomical region;

introducing a fluid into a proximal end of said tube, a length of said tube defining said infusion section, said infusion section having a plurality of exit holes in side walls of said tube and concentrically enclosing a tubular coil spring, a lumen being defined within said tube and spring, said spring having adjacent coils in contact with one another so that fluid within said lumen and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils and through said exit holes;

allowing said fluid to flow into said spring; and

bringing the fluid within said spring to a pressure greater than or equal to said threshold dispensation pressure;

wherein said fluid is dispensed from said lumen by flowing radially between said coils and through said exit holes.

10. A method of manufacturing a catheter for the delivery of fluid to an anatomical region, comprising the steps of:

providing a distally closed tube, a length of said tube defining an infusion section of said tube, said infusion section having exit holes in side walls of said tube; and

inserting a tubular coil spring concentrically into said infusion section, a lumen being defined within said tube and spring, said spring having adjacent coils in contact with one another so that fluid within said lumen and below a threshold dispensation pressure is prevented from exiting said lumen by flowing radially between said coils, said spring having the property of stretching when the fluid pressure is greater than or equal to said threshold dispensation pressure and permitting the fluid to be dispensed from said lumen by flowing radially between said coils and through said exit holes.