Devices for treating circadian rhythm disorders using LED's

• US 6,350,275 B1
• Filed: 06/09/1998
• Issued: 02/26/2002
• Est. Priority Date: 06/09/1997
• Status: Expired due to Term

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford University)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford University)
• Inventors: Stevenson, David K., Vreman, Hendrik J.
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/094,231
• Time in Patent Office: 1,358 Days
• Field of Search: 607/88-92, 606/27, 606/33, 351/200, 351/203
• US Class Current: 607/88
• CPC Class Codes: A42B 1/244 Means for mounting lamps
• CPC Class Codes: A61M 2021/0044 by the sight sense
• CPC Class Codes: A61M 2021/0083 especially for waking up
• CPC Class Codes: A61M 21/00 Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
• CPC Class Codes: A61N 2005/0648 the light being directed to the eyes
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 2005/0663 Coloured light
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body
• CPC Class Codes: A61N 5/0618 Psychological treatment
• CPC Class Codes: A61N 5/0621 Hyperbilirubinemia, jaundice treatment

Abstract

A device is provided for treating a circadian rhythm disorder in a subject. The device includes a plurality of light emitting diodes (LED'"'"'s), preferably blue to green; a mounting to which the LED'"'"'s are connected: a material for positioning the LED'"'"'s within 3 cm of the subject, with an orientation toward the subject; a portable power supply electrically connected to the LED'"'"'s; and a control connected to the LED'"'"'s for altering the operation of the LED'"'"'s. The device is sufficiently light and compact to be comfortably worn by the subject. One or more such devices are used to deliver light to a subject'"'"'s retinas, to the subject'"'"'s vascular tissue, or simultaneously to both the retinas and the vascular tissue. For illumination of the retina, small chip-type LED'"'"'s are integrated into the frames of eyeglasses and positioned to direct light into the eyes of the subject. For illumination of the vascular tissue, an array of lens or chip type LED'"'"'s are contained in a casing that is secured against the skin of the subject. The devices can be used independently of each other, or can be used in combination for more effective and/or flexible treatment.

Claims

1. A method for treating circadian rhythm disorders experienced by a subject, the method comprising:

(a) illuminating the vascular tissue beneath the skin of the subject with light produced by a portable device worn by the subject, wherein the device comprises a plurality of light emitting diodes (LED'"'"'s) positioned within 3 cm of and oriented toward the subject for illuminating the subject, a power supply connected to the LED'"'"'s, and a control connected to the LED'"'"'s; and

(b) simultaneously illuminating the subject with light produced by an additional device worn by the subject.

2. The method of claim 1 wherein the LED'"'"'s comprise LED'"'"'s having wavelengths in the range from 420 nm to 575 nm.

3. The method of claim 1 wherein the LED'"'"'s comprise chip-type LED'"'"'s.

4. The method of claim 1 wherein the LED'"'"'s comprise GaN-based LED'"'"'s.

5. A method for treating circadian rhythm disorders experienced by a subject, the method comprising:

(a) illuminating the subject with light produced by a portable device worn around a portion of the subject'"'"'s body, wherein the device comprises a plurality of light emitting diodes (LED'"'"'s) positioned within 3 cm of and oriented toward the subject for illuminating the subject, a power supply connected to the LED'"'"'s, and a control connected to the LED'"'"'s; and

(b) simultaneously illuminating the subject with light produced by an additional device worn by the subject.

6. The method of claim 5 wherein the LED'"'"'s comprise LED'"'"'s having wavelengths in the range from 420 nm to 575 nm.

7. The method of claim 5 wherein the LED'"'"'s comprise chip-type LED'"'"'s.

8. The method of claim 5 wherein the LED'"'"'s comprise GaN-based LED'"'"'s.

9. A method for treating circadian rhythm disorders experienced by a subject, the method comprising:

illuminating the subject with light produced by a portable device worn by the subject, wherein the device comprises a plurality of light emitting diodes (LED'"'"'s) positioned within 3 cm of and oriented toward the subject for illuminating the subject, a power supply connected to the LED'"'"'s, and a control connected to the LED'"'"'s; and

simultaneously illuminating the subject with light produced by an additional device worn by the subject.

10. The method of claim 9, wherein the LED'"'"'s comprise LED'"'"'s having wavelengths in the range from 420 nm to 575 nm.

11. The method of claim 9, wherein the LED'"'"'s comprise chip-type LED'"'"'s.

12. The method of claim 9, wherein the LED'"'"'s comprise GaN-based LED'"'"'s.