Methods for forming anastomoses using magnetic force

• US 6,352,543 B1
• Filed: 04/29/2000
• Issued: 03/05/2002
• Est. Priority Date: 04/29/2000
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Ventrica, Inc. (Medtronic Plc)
• Inventors: Cole, David H.
• Primary Examiner(s): Reip, David O.
• Assistant Examiner(s): Woo, Julian W.
• Application Number:
  US09/562,599
• Time in Patent Office: 675 Days
• Field of Search: 606/151, 606/153, 606/154, 606/155, 606/156, 606/215, 606/216, 128/898
• US Class Current: 606/153
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/0469 Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/00252 for by-pass connections, i.e. connections from heart chamber to blood vessel or from blood vessel to blood vessel
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00876 magnetic
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61B 2017/1132 End-to-end connections
• CPC Class Codes: A61B 2017/1135 End-to-side connections, e.g. T- or Y-connections
• CPC Class Codes: A61B 2017/1139 Side-to-side connections, e.g. shunt or X-connections
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/2493 Transmyocardial revascularisation [TMR] devices
• CPC Class Codes: A61F 2/94 : Stents retaining their form, i.e. not being deformable, after placement in the predetermined place
• CPC Class Codes: A61F 2002/30079 : magnetic
• CPC Class Codes: A61F 2210/0076 : multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2210/009 : magnetic
• CPC Class Codes: H01F 41/026 : protecting methods against environmental influences, e.g. oxygen, by surface treatment magnetic particles with skin H01F1/061, H01F1/09, H01F1/24, H01F1/33 and G11B5/706
• CPC Class Codes: H01F 7/0263 : Closures, bags, bands, engagement devices with male and female parts

Abstract

Methods and devices for forming an anastomosis between hollow bodies using magnetic force to couple anastomotic securing components and create a fluid-tight connection between the lumens of the hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created without using suture or any other type of mechanical fasteners, although any such attachment means may be used in conjunction with the magnetic attachment The securing components have magnetic, ferromagnetic or electromagnetic properties and may include one or more materials, for example, magnetic and nonmagnetic materials arranged in a laminated structure. The system of anastomotic securing components may he used in many different applications including the treatment of cardiovascular disease, peripheral vascular disease, forming AV shunts for dialysis patients, etc., and may be sized and configured for forming an anastomosis to a specific hollow body, for example, a coronary artery or the aorta.

Claims

1. A method for forming an anastomosis between first and second vessels using magnetic force, the method comprising steps of:

selecting a first vessel having a lumen;

selecting a second vessel having a lumen;

securing a first anastomotic component to the first vessel to define a first contact surface, the first contact surface being formed at least in part by an exposed portion of the first anastomotic component;

securing a second anastomotic component to the second vessel to define a second contact surface; and

using magnetic force to create an anastomosis between the first and second vessels by contacting the exposed portion of the first contact surface with the second contact surface.

2. The method of claim 1, wherein the second contact surface is formed at least in part by an exposed portion of the second anastomotic component.

3. The method of claim 2, wherein the exposed portions of the first and second anastomotic components contact one another.

4. The method of claim 1, wherein the first vessel is a coronary artery and the second vessel is a graft selected from the group consisting of natural blood vessels and vessels formed of synthetic material.

5. The method of claim 1, wherein the exposed portion of the first anastomotic component contacts the second vessel.

6. The method of claim 1, wherein the magnetic force is sufficient to maintain the anastomosis between the first and second vessels.

7. The method of claim 6, wherein only magnetic force is used to form the anastomosis between the first and second vessels.

8. The method of claim 1 further comprising the step of maintaining the full size of the opening in the second vessel.

9. The method of claim 1, wherein each of the first and second anastomotic components includes a material selected from the group consisting of magnetic, electromagnetic and ferromagnetic materials.

10. The method of claim 1, further comprising the step of preventing the first and second anastomotic components from moving toward each other beyond a predetermined distance.

11. The method of claim 1, wherein at least one of the first and second anastomotic components is secured to a respective vessel without penetrating the tissue of the vessel.

12. The method of claim 1, wherein at least one of the first and second anastomotic components is secured to a respective vessel without everting the vessel.

13. The method of claim 12, wherein the first and second anastomotic components are secured to the respective vessels without everting either vessel.

14. The method of claim 1, wherein the anastomosis is formed without using glue.

15. The method of claim 1, further comprising the step of forming a magnetic anastomosis between the second vessel and a third vessel so as to place the third vessel in communication with the first vessel.

16. The method of claim 15, wherein the first and second anastomotic components are unconnected.

17. A method for forming an anastomosis between first and second vessels using magnetic force, the method comprising steps of:

selecting a first vessel having a lumen, selecting a second vessel having a lumen;

securing a first anastomotic component to the first vessel by capturing tissue of the first vessel between two portions of the first anastomotic component that respectively contact an intimal surface and an exterior surface of the first vessel, wherein the first anastomotic component is secured to the first vessel by compressing the tissue of the first vessel between the two portions of the component, the two portions of the first anastomotic component compressing the intimal and exterior surfaces of the first vessel as a result of magnetic force;

securing a second anastomotic component to the second vessel; and

using magnetic force between the first and second components to create an anastomosis that places the lumens of the first and second vessels in communication.

18. The method of claim 17, wherein the two portions of the first anastomotic component are separate members.

19. The method of claim 17, wherein the second anastomotic component is secured to the second vessel without contacting an intimal tissue surface of the second vessel.

20. The method of claim 17, wherein the second anastomotic component is secured to an end of the second vessel and is coupled to the first anastomotic component to form an end-to-side anastomosis.

21. The method of claim 17, wherein at least one of the first and second vessels includes synthetic material.

22. The method of claim 17, wherein the first vessel is a coronary artery and the second vessel is a graft selected from the group consisting of natural blood vessels and vessels formed of synthetic material.

23. The method of claim 17, wherein the magnetic force is sufficient to maintain the anastomosis between the first and second vessels.

24. The method of claim 17, further comprising the step of maintaining the fall size of an opening in the second vessel.

25. The method of claim 17, wherein each of the first and second anastomotic components includes a material selected from the group consisting of magnetic, electromagnetic and ferromagnetic materials.

26. The method of claim 17, further comprising the step of preventing the first and second anastomotic components from moving toward each other beyond a predetermined distance.

27. The method of claim 17, wherein at least one of the first and second anastomotic components is secured to a respective vessel without penetrating the tissue of the vessel.

28. The method of claim 17, wherein at least one of the first and second anastomotic components is secured to a respective vessel without everting the vessel.

29. The method of claim 28, wherein the first and second anastomotic components are secured to the vessels without everting either vessel.

30. The method of claim 17, wherein the anastomosis is formed without using glue.

31. The method of claim 17, further comprising the step of forming a magnetic anastomosis between the second vessel and a third vessel so as to place the third vessel in communication with the first vessel.

32. The method of claim 17, wherein the first and second anastomotic components are unconnected.

33. The method of claim 17, wherein only magnetic force is used to couple the first and second anastomotic components together.

34. The method of claim 17, wherein the first anastomotic component is secured to an end of the first vessel while the second anastomotic component is secured to a side wall of the second vessel, and the first and second anastomotic components are coupled to form an end-to-side anastomosis.

35. The method of claim 17, wherein the anastomosis is a side-to-side anastomosis.

36. A method for forming an anastomosis between first and second vessels using magnetic force, the method comprising steps of:

selecting a first vessel having a side wall and a lumen;

selecting a second vessel having a side wall and a lumen;

securing a first anastomotic component to the first vessel by magnetic force;

securing a second anastomotic component to the second vessel by a non-magnetic attachment; and

using magnetic force between the first and second anastomotic components to create an anastomosis that places the lumens of the first and second vessels in communication;

wherein the magnetic force between the first and second anastomotic components is sufficient to maintain the anastomosis between the first and second vessels without interconnecting the first and second anastomotic components.

37. The method of claim 36, wherein only magnetic force is used to create the anastomosis.

38. The method of claim 36, wherein the first vessel is a coronary artery and the second vessel is a graft selected from the-group consisting of natural blood vessels and vessels formed of synthetic material.

39. The method of claim 36, wherein only magnetic force between the first and second anastomotic components is used to maintain the anastomosis between the first and second vessels.

40. The method of claim 36, further comprising the step of maintaining the full size of an opening in the side wall of the second vessel.

41. The method of claim 36, wherein each of the first and second anastomotic components includes a material selected from the group consisting of magnetic, electromagnetic and ferromagnetic materials.

42. The method of claim 36, farther comprising the step of preventing the first and second anastomotic components from moving toward each other beyond a predetermined distance.

43. The method of claim 36, wherein at least one of the first and second anastomotic components is secured to a respective vessel without penetrating the tissue of the vessel.

44. The method of claim 36, wherein at least one of the first and second anastomotic components is secured to a respective vessel without everting the vessel.

45. The method of claim 44, wherein the first and second anastomotic components are secured to the first and second vessels without everting either vessel.

46. The method of claim 36, wherein the anastomosis is formed without using glue.

47. The method of claim 36, farther comprising the step of forming a magnetic anastomosis between the second vessel and a third vessel so as to place the third vessel in communication with the first vessel.

48. The method of claim 36, wherein the first and second anastomotic components are unconnected.

49. The method of claim 36, wherein the anastomosis is a side-to-side anastomosis.

50. A method for forming an anastomosis between first and second vessels using magnetic force, the method comprising steps of:

selecting a first vessel having a lumen;

selecting a second vessel having a lumen;

securing a first anastomotic component to the first vessel by capturing tissue of the first vessel between two portions of the first anastomotic component, the two portions of the first anastomotic component respectively contacting an intimal surface and an exterior surface of the first vessel;

securing a second anastomotic component to the second vessel, the second anastomotic component being secured to the second vessel without contacting an intimal surface of the second vessel; and

using magnetic force to create an anastomosis that places the lumens of the first and second vessels in communication.

51. The method of claim 50, wherein the first anastomotic component is secured to a side wall of the first vessel by compressing the tissue of the side wall between the two portions of the component.

52. The method of claim 50, wherein the two portions compress the intimal and exterior surfaces of the first vessel side wall as a result of magnetic force.

53. The method of claim 50, wherein the first anastomotic component is secured to an end of the first vessel and is coupled to the second anastomotic component to form an end-to-side anastomosis.

54. The method of claim 50, wherein magnetic force is used to create a side-to-side anastomosis.

55. The method of claim 50, wherein the magnetic force between the first and second anastomotic components is sufficient to maintain the anastomosis between the first and second vessels.

56. The method of claim 50, wherein only magnetic force is used to secure the first anastomotic component to the first vessel.

57. The method of claim 50, further comprising the step of maintaining the full size of an opening in the second vessel.

58. The method of claim 50, wherein each of the first and second anastomotic components includes a material selected from the group consisting of magnetic, electromagnetic and ferromagnetic materials.

59. The method of claim 50, further comprising the step of preventing the first and second anastomotic components from moving toward each other beyond a predetermined distance.

60. The method of claim 50, wherein at least one of the first and second anastomotic components is secured to a respective vessel without penetrating the tissue of the vessel.

61. The method of claim 50, wherein at least one of the first and second anastomotic components is secured to a respective vessel without everting the vessel.

62. The method of claim 50, wherein the first and second anastomotic components are secured to the vessels without everting either vessel.

63. The method of claim 50, wherein the first and second anastomotic components are coupled by magnetic force without being mechanically connected.

64. The method of claim 50, wherein the first vessel is a coronary artery and the second vessel is a graft selected from the group consisting of natural blood vessels and vessels formed of synthetic material.

65. The method of claim 50, wherein the anastomosis is a side-to-side anastomosis.