Cardiac rhythm management system promoting a trial pacing

• US 6,353,759 B1
• Filed: 10/20/2000
• Issued: 03/05/2002
• Est. Priority Date: 05/21/1999
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Stahmann, Jeffrey E., Hartley, Jesse W., Kramer, Andrew P., Krig, David B.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/693,402
• Time in Patent Office: 501 Days
• Field of Search: 607/9, 607/17
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/39622 Pacing therapy
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

A cardiac rhythm management system includes an atrial pacing preference (APP) filter for promoting atrial pacing. The APP filter includes an infinite impulse response (IIR) or other filter that controls the timing of delivery of atrial pacing pulses. The atrial pacing pulses are delivered at an APP-indicated pacing rate that is typically at a small amount above the intrinsic atrial heart rate. For sensed beats, the APP indicated rate is increased until it becomes slightly faster than the intrinsic atrial heart rate. The APP-indicated pacing rate is then gradually decreased to search for the underlying intrinsic atrial heart rate. Then, after a sensed atrial beat, the APP filter again increases the pacing rate until it becomes faster than the intrinsic atrial rate by a small amount. As a result, most atrial heart beats are paced, rather than sensed. This decreases the likelihood of the occurrence of an atrial tachyarrhythima, such as atrial fibrillation. The decreased likelihood of atrial tachyarrhythmia, in turn, decreases the likelihood of inducing a ventricular arrhythmia, either as a result of the atrial tachyarrhythmia, or as the result of delivering a defibrillation shock to treat the atrial tachyarrhythmia.

Claims

1. A cardiac rhythm management system, including:

an atrial sensing circuit;

a controller, the controller including;

an A—

A interval timer;

a first register, for storing a first indicated pacing interval;

a filter, updating the first indicated pacing interval based on the A—

A interval timer and the first register; and

an atrial therapy circuit, providing pacing therapy based at least partially on the first indicated pacing interval.

2. The system of claim 1, further including a sensor, and in which the controller further includes a second register, for storing a second indicated pacing interval that is based on a signal received from the sensor, and in which the atrial therapy circuit provides pacing therapy based on one or more of the first and second indicated pacing intervals.

3. The system of claim 1, in which the filter includes an infinite impulse response (IIR).

4. The system of claim 3, wherein the IIR filter updates the first indicated pacing interval (T_n) according to:

T_n=A·

AA_n+B·

T<sub>n−

1</sub>, if AA_n is concluded by an intrinsic beat, otherwise is updated according to T_n=C·

AA_n+D·

T<sub>n−

1</sub>, if AA_n is concluded by a paced beat, where A, B, C and D are coefficients, and AA_n is the A—

A interval duration provided by the A—

A interval timer, and T<sub>n−

1</sub> is a previous value of the first indicated pacing interval, and wherein at least one of A, B, C or D is a function of heart rate.

5. The system of claim 4, in which T_n−

1 is the immediately preceding value of the first indicated pacing interval.

6. The system of claim 1, in which the filter includes a finite impulse response (FIR).

7. The system of claim 1, in which the filter includes an averager.

8. The system of claim 7, in which the filter includes a weighted averager.

9. The system of claim 1, further comprising a remote programmer, adapted for communication with the controller.

10. The system of claim 1, wherein the filter updates the first indicated pacing interval (T_n) according to T_n=a·

w·

AA_n+(1−

w)·

T<sub>n−

1</sub>, where a and w are coefficients, AA_n is a most recent A—

A interval duration, and T<sub>n−

1</sub> is a previous value of the first indicated pacing interval.

11. The system of claim 10, in which T_n−

1 is the immediately preceding value of the first indicated pacing interval.

12. The system of claim 1, wherein the filter updates the first indicated pacing interval (T_n) according to:

T_n=a·

w·

AA_n+(1−

w)·

T<sub>n−

1</sub>, if AA_n is concluded by an intrinsic beat, otherwise is carried out according to T_n=b·

w·

AA_n+(1−

w)·

T<sub>n−

1</sub>, if AA_n is concluded by a paced beat, where b is a coefficient.

13. The system of claim 12, wherein at least one of a, b, or w is a function of heart rate.

14. The system of claim 1, wherein the controller obtains A—

A intervals between atrial beats and computes a first indicated pacing interval based at least on a most recent A—

A interval duration and a previous value of the first indicated pacing interval.

15. The system of claim 14, wherein the controller adjusts the first indicated pacing interval, by differently weighting at least one of (1) the most recent A—

A interval duration, or (2) the previous value of the first indicated pacing interval, if the most-recent A—

A interval is concluded by a paced beat than if the most recent A—

A interval is concluded by a sensed beat.

16. The system of claim 14, wherein the controller computes the first indicated pacing interval (T_n) according to:

T_n=a·

w·

AA_n+(1−

w)·

T<sub>n−

1</sub>, if AA_n is concluded by an intrinsic beat, otherwise T_n is computed according to T_n=b·

w·

AA_n+(1−

w)·

T<sub>n−

1</sub>, if AA_n is concluded by a paced beat, where b is a coefficient.

17. The system of claim 16, wherein at least one of a, b, or w is a function of heart rate.

18. The system of claim 1, further including a sensor, and in which the controller computes a second indicated pacing interval based on signals received from the sensor, and in which the atrial therapy circuit provides pacing therapy that is also based on the second indicated pacing interval.

19. The system of claim 1, in which the atrial therapy circuit provides pacing therapy at a rate that generally exceeds an intrinsic atrial heart rate.

20. The system of claim 19, in which the first register stores an immediately preceding value of the first indicated pacing interval.

21. An implantable cardiac rhythm management device, including:

an atrial sensing circuit;

an atrial therapy circuit, providing atrial pacing therapy based on a first indicated pacing interval;

a controller, the controller including;

an A—

A interval timer;

a first register, for storing the first indicated pacing interval; and

an infinite impulse response (IIR) filter that updates the first indicated pacing interval (T_n) according to;

T_n=A·

AA_n+B·

T<sub>n−

1</sub>, if AA_n is concluded by an intrinsic beat, otherwise is updated according to T_n=C·

AA_n+D·

T<sub>n−

1</sub>, if AA_n is concluded by a paced beat, where A, B, C and D are coefficients, and AA_n is the A—

A interval duration provided by the A—

A interval timer, and T<sub>n−

1</sub> is the previous value of the first indicated pacing interval.

22. The implantable cardiac rhythm management device of claim 21, wherein at least one of A, B, C or D is a function of heart rate and C and D are different values.

23. The implantable cardiac rhythm management device of claim 22, wherein C and A are different values.

24. The system of claim 21, in which the atrial therapy circuit provides pacing therapy at a rate that generally exceeds an intrinsic atrial heart rate.

25. The system of claim 24, in which the first register stores an immediately preceding value of the first indicated pacing interval.

26. The system of claim 21, in which T_n−

1 is the immediately preceding value of the first indicated pacing interval.