Method and apparatus for loading radioactive seeds into brachytherapy needles

• US 6,358,195 B1
• Filed: 03/09/2000
• Issued: 03/19/2002
• Est. Priority Date: 03/09/2000
• Status: Expired due to Fees

• Current Assignee: Neose Technologies, Inc.
• Original Assignee: Neose Technologies, Inc.
• Inventors: Horzewski, Michael J., Klofstad, Jason, Green, Thomas C.
• Primary Examiner(s): Lacyk, John P.
• Application Number:
  US09/522,248
• Time in Patent Office: 740 Days
• Field of Search: 600/1-8
• US Class Current: 600/7
• CPC Class Codes: A61M 2210/166 Prostate
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027
• CPC Class Codes: A61M 5/329 characterised by features of the needle shaft
• CPC Class Codes: A61N 2005/1009 Apparatus for loading seeds into magazines or needles
• CPC Class Codes: A61N 2005/101 Magazines or cartridges for seeds
• CPC Class Codes: A61N 2005/1011 Apparatus for permanent insertion of sources
• CPC Class Codes: A61N 5/1007 Arrangements or means for the introduction of sources into the body
• CPC Class Codes: A61N 5/1027 Interstitial radiation therapy

Abstract

Methods and apparatus are provided for loading therapeutic materials into brachytherapy needles. The apparatus comprises a loading tube with a lumen and two transverse slots, and radioactive seed and spacer cartridges slidably received within the transverse slots. The apparatus may be used in conjunction with a standard brachytherapy plunger and needle coupled to, respectively, the proximal and distal ends of the loading tube. The plunger dislodges seeds and spacers from the cartridge chambers to load the needle with a predetermined packing arrangement.

Claims

1. Apparatus for loading therapeutic materials into brachytherapy needles comprising:

a loading tube with proximal and distal ends, a lumen extending therebetween, and first and second transverse slots disposed between the proximal and distal ends;

a first cartridge comprising a plurality of seed chambers, the first cartridge configured to be manually advanced through the first transverse slot; and

a second cartridge comprising a plurality of spacer chambers, the second cartridge configured to be manually advanced through the second transverse slot.

2. The apparatus of claim 1 further comprising a plunger configured for reciprocation in the lumen.

3. The apparatus of claim 1 further comprising means for retaining a spacer in each one of the plurality of spacer chambers.

4. The apparatus of claim 1 further comprising means for retaining a radioactive seed in each one of the plurality of seed chambers.

5. The apparatus of claim 1 wherein the distal end of the loading tube is adapted to be disposed within an interior lumen of a brachytherapy needle.

6. The apparatus of claim 1 wherein the first cartridge is fabricated from a shielding material.

7. The apparatus of claim 6 wherein the shielding material is lead.

8. The apparatus of claim 1 wherein the first and second cartridges are fabricated from a transparent or translucent material.

9. The apparatus of claim 8 wherein the material is a polymer.

10. A method for loading therapeutic materials into brachytherapy needles comprising:

providing apparatus comprising a loading tube with proximal and distal ends, a lumen extending therebetween, and first and second transverse slots, a first cartridge comprising a plurality of seed chambers loaded with radioactive seeds, the first cartridge configured to be manually advanced through the first transverse slot, a second cartridge comprising a plurality of spacer chambers loaded with spacers, the second cartridge configured to be manually advanced through the second transverse slot, a plunger, and a brachytherapy needle;

coupling the distal end of the loading tube within a lumen of the brachytherapy needle;

sliding the cartridges within the transverse slots to align subsequent seeds and spacers with the loading tube lumen;

inserting a distal end of the plunger within the loading tube lumen; and

distally advancing the plunger relative to the loading tube to dislodge a radioactive seed or a spacer from a cartridge chamber aligned with the loading tube lumen and to advance the seed or spacer into the needle lumen.

11. The method of claim 10 further comprising proximally retracting the plunger.

12. The method of claim 10 further comprising loading the needle with seeds and spacers in a predetermined packing arrangement.

13. Apparatus for loading therapeutic materials into brachytherapy needles comprising:

a loading tube having proximal and distal ends, a lumen extending therebetween, and first and second transverse slots disposed between the proximal and distal ends;

first and second cartridges configured to be manually advanced through the first and second transverse slots, the first and second cartridges comprising a plurality of first and second chambers, respectively; and

a plunger disposed for reciprocation within the lumen.

14. The apparatus of claim 13 further comprising means for retaining a spacer in each one of the plurality of second chambers.

15. The apparatus of claim 13 further comprising means for retaining a radioactive seed in each one of the plurality of first chambers.

16. The apparatus of claim 13 wherein the distal end of the loading tube is adapted to be disposed within an interior lumen of a brachytherapy needle.

17. The apparatus of claim 13 wherein the first cartridge is fabricated from a shielding material.