Method for calibrating a radiation detection system

• US 6,362,472 B1
• Filed: 10/22/1999
• Issued: 03/26/2002
• Est. Priority Date: 10/22/1999
• Status: Expired due to Term

• Current Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Yarnall, Stephen T., Gormley, Jerome E.
• Primary Examiner(s): Epps, Georgia
• Assistant Examiner(s): HANIG, RICHARD E
• Application Number:
  US09/425,481
• Time in Patent Office: 886 Days
• Field of Search: 250/252.1 R, 250/363.09, 250/303, 600/436
• US Class Current: 250/252.1
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: G01T 1/161 Applications in the field of nuclear medicine, e.g. in vivo counting apparatus for radiation diagnosis A61B6/00

Abstract

An automatic calibration method is provided for calibrating a radiation detection system for processing counts from a known radiation source. A probe is positioned near the radiation source, which may be the surgical injection site of a radionucleide. A control unit generates audible and/or visual feedback signals to cue the operator as to where to position the probe relative to the radiation source, in order to obtain a pulse frequency (count rate) in an optimal range for processing. The control unit then automatically identifies a probe output corresponding to a peak energy level and calibrates the system to that peak. Once calibrated, the system may set an energy acceptance window having a mathematical relationship to the peak energy level, whereby the radiation detection system thereinafter processes only counts corresponding to energy levels falling within the energy acceptance window.

Claims

1. A method for calibrating a radiation detection system for processing and analyzing counts from a radiation source, whereby a count is a single radioactive event having an energy level, said method comprising the steps of:

a) positioning a probe of said radiation detection system near said radiation source;

b) generating a plurality of electronic pulses, each of said electronic pulses having a pulse magnitude proportional to the energy level of a count detected by said probe;

c) counting said plurality of electronic pulses and calculating a pulse frequency;

d) generating a low-count feedback signal when said pulse frequency is less than a predetermined low-count frequency;

e) generating a high-count feedback signal when said pulse frequency is greater than a predetermined high-count frequency;

f) generating a optimal-count range feedback signal when said pulse frequency is greater than or equal to said predetermined low-count frequency and is less than or equal to said predetermined high-count frequency;

g) measuring a plurality of pulse magnitudes when said optimal-count range feedback signal is provided;

h) grouping said plurality of pulse magnitudes into a plurality of pulse magnitude ranges, and each pulse magnitude range has a width;

i) determining the number of pulse magnitudes corresponding to each of said plurality of pulse magnitude ranges;

j) determining a peak pulse magnitude range from said plurality of pulse magnitude ranges, whereby said peak pulse magnitude range has the maximum number of corresponding pulse magnitudes;

k) assigning an energy level to each of said plurality of pulse magnitude ranges, whereby a peak energy level having a known, characteristic value according to said radiation source is assigned to said peak pulse magnitude range, and remaining pulse magnitude ranges are assigned energy levels that are lower than said peak energy level; and

l) setting an energy acceptance window comprising a continuous portion of said energy levels containing said peak energy level, said energy acceptance window containing a lowest energy level having a first predetermined relationship to said peak energy level, whereby said radiation detection system thereinafter processes only pulses corresponding to an energy level falling within said energy acceptance window.

2. The method of claim 1 wherein said energy acceptance window contains a highest energy level having a second predetermined relationship to said peak energy level.

3. The method of claim 1 wherein said low-count feedback signal comprises an audible feedback.

4. The method of claim 1 wherein said low-count feedback signal comprises a visual feedback.

5. The method of claim 1 wherein said high-count feedback signal comprises an audible feedback.

6. The method of claim 1 wherein said high-count feedback signal comprises a visual feedback.

7. The method of claim 1 wherein said optimal-count range feedback signal comprises an audible feedback.

8. The method of claim 1 wherein said optimal-count range feedback signal comprises a visual feedback.

9. The method of claim 1 wherein said predetermined low-count frequency is approximately 100 counts per second.

10. The method of claim 1 wherein said predetermined high-count frequency is approximately 4000 counts per second.

11. The method of claim 1 wherein said plurality of counts is a predetermined plurality of counts.

12. The method of claim 11 wherein said predetermined plurality of counts is approximately 1000 counts.

13. The method of claim 1 wherein said width of each of said pulse magnitude ranges is a predetermined width.

14. The method of claim 13 wherein said predetermined width of each of said pulse magnitude ranges is approximately in the range of 1-5 Kilo-electron Volts.

15. The method of claim 1 wherein said first predetermined relationship of said lowest limit energy level to said peak energy level is a predetermined percentage of said peak energy level.

16. The method of claim 15 wherein said predetermined percentage of said peak energy level is approximately in the range of 70-90 percent.