Anti-clotting methods and apparatus for indwelling catheter tubes

• US 6,364,867 B2
• Filed: 07/01/1999
• Issued: 04/02/2002
• Est. Priority Date: 07/01/1999
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Catheter Innovations, Inc. (Boston Scientific Corporation)
• Inventors: Moorehead, H. Robert, Wise, Marcia A.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): Sirmons, Kevin C.
• Application Number:
  US09/345,892
• Publication Number:
  US 20020016584A1
• Time in Patent Office: 1,006 Days
• Field of Search: 604/256, 604/266, 604/267, 604/268, 604/269, 604/509, 604/167.01, 604/167.06
• US Class Current: 604/509
• CPC Class Codes: A61M 2025/0018 having a plug, e.g. an inflatable plug for closing catheter lumens
• CPC Class Codes: A61M 2025/0031 characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
• CPC Class Codes: A61M 2025/0079 Separate user-activated means, e.g. guidewires, guide tubes, balloon catheters or sheaths, for sealing off an orifice, e.g. a lumen or side holes, of a catheter
• CPC Class Codes: A61M 25/0028 characterized by features relating to at least one lumen located at the proximal part of the catheter, e.g. alterations in lumen shape or valves catheter hubs A61M25/0097
• CPC Class Codes: A61M 25/003 characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves catheter tips A61M25/0067
• CPC Class Codes: A61M 25/0032 characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

Enabled or activated closure and sealing devices in the form of closure balloons, and related methods, are disclosed, which substantially preclude entry and clotting of blood at the distal end of a lumen of an indwelling catheter tube during times when flow therein is not occurring. The closure and sealing balloon is disabled or deactivated to accommodate flow, without clotting, through the lumen of the catheter tube when flow therein is resumed.

Claims

1. A method of addressing the problem of clotting in an idle catheter tube indwelling within a vessel of a medical patient comprising the acts of:

advancing a deflated balloon along an entirely unobstructed hollow interior of the idle indwelling catheter tube so that the balloon is radially aligned at least in part with a distal end of the catheter tube;

inflating the balloon to radially contiguously engage, close, seal and occlude the entire hollow interior at the distal end of the idle indwelling catheter tube, without expanding the distal end, to deny blood access to the hollow interior.

2. A method according to claim 1 further comprising an act of purging the hollow interior of the catheter tube in a proximal-to-distal direction with a suitable liquid under pressure.

3. A method according to claim 2 wherein the purging act precedes the inflating act.

4. A method according to claim 2 wherein the purging act follows the inflating act, the pressure of the liquid temporarily deforming the balloon and overriding the occlusion of the hollow interior of the catheter tube.

5. A method according to claim 1 further comprising an act of deflating the previously inflated balloon to eliminate the occlusion of the hollow interior and causing flow through the hollow interior of the catheter tube.

6. A method according to claim 5 further comprising an act of withdrawing the balloon along the hollow interior of the catheter tube after the deflating act and before the causing act.

7. A method of addressing the problem of clotting in idle ingress and egress companion unobstructed catheter tubes indwelling within a vessel of a medical patient, comprising the acts of:

advancing a deflated balloon along an entirely hollow and unobstructed lumen of each idle ingress and egress catheter tube to a position at least partially radially with a distal end of each;

inflating the respective balloons to radially span cross sectionally the lumen and radially contiguously engage, close, seal and occlude the lumen at the distal end of each catheter tube, thereby preventing blood infiltration and clotting by denying blood access, to the entirely occluded lumen of each catheter tube;

purging the lumen of one or both catheter tubes in a proximal-to-distal direction with a suitable liquid under pressure.

8. A method of addressing the problem of clotting in a catheter tube indwelling within a vessel of a patient comprising the acts of:

terminating flow along a hollow interior passageway of the indwelling catheter tube;

after the terminating act, inflating a balloon to expand the balloon radially across the interior passageway and contiguously radially engage, close, seal and occlude the entire hollow cross section of the interior passageway at a distal end of the indwelling catheter tube to deny blood in the vessel access to the hollow passageway thereby preventing clotting within the catheter tube.

9. A method according to claim 8 further comprising an act of purging the hollow interior of the catheter tube in a proximal-to-distal direction with a suitable liquid under pressure.

10. A method according to claim 9 wherein the purging act precedes the inflating act.

11. A method according to claim 9 wherein the purging act follows the inflating act, the pressure of the liquid temporarily overriding the occlusion of the interior passageway of the catheter tube.

12. A method according to claim 8 further comprising acts of deflating the previously inflated balloon to eliminate the occlusion of the hollow passageway and causing flow through the hollow interior passageway of the catheter tube.

13. A method of addressing the problem of clotting in ingress and egress companion catheter tubes indwelling within a vessel of a medical patient, comprising the acts of:

terminating ingress and egress flow along hollow interior passageways of the indwelling catheter tubes, respectively;

after the terminating step, radially inflating balloons so that each balloon radially spans the interior passageway of the associated catheter tube occluding the same by engaging, closing and sealing the respective hollow interior passageways at the distal ends of the indwelling ingress and egress catheter tubes to prevent clotting within either catheter tube by denying blood in the vessel access to the hollow interior passageways.

14. A method according to claim 13 further comprising acts of purging one or both hollow interior passageways in a proximal-to-distal direction with a suitable liquid under pressure.

15. A method according to claim 14 wherein each purging step precedes the inflating step.

16. A method according to claim 14 wherein the purging step follows the inflating step, and further comprising an act of controlling the pressure of the liquid thereby temporarily unsealing the inflated balloons and overriding the occlusion of the hollow interior passageways of the indwelling catheter tubes.

17. A method according to claim 13 further comprising acts of deflating the previously inflated balloons to eliminate the occlusion of the hollow interior passageways and causing ingress and egress flow through the hollow interior passageways, respectively.

18. A method of addressing the problem of clotting in an idle catheter tube placed within a vessel of a medical patient comprising the acts of;

advancing a deflated balloon along a hollow interior of the idle catheter tube to a distal end thereof prior to placement of the catheter tube in the vessel;

inflating the balloon so that the balloon radially expands without significant axial displacement to diametrally span the hollow interior to physically engage, close, seal and occlude the hollow interior at the distal end of the catheter tube;

collectively introducing the distal end of the catheter tube and the inflated balloon into the vessel, whereby clotting within the hollow interior is prevented by the denial of entry of blood into the hollow interior of the catheter tube.

19. A method according to claim 18 further comprising an act of deflating the indwelling previously inflated balloon to eliminate the occlusion of the hollow interior thereby accommodating liquid flow through the hollow interior of the catheter tube.

20. A method of addressing the problem of clotting in idle ingress and egress companion catheter tubes placed within a vessel of a medical patient, comprising the acts of:

advancing a deflated balloon along a hollow interior of each idle ingress and egress catheter tube to a distal end of each prior to placement of either catheter tube in the vessel;

inflating the respective balloons so that the balloon radially expands to diametrally span the hollow interior of each catheter tube and to contiguously close, seal and occlude the hollow interior of each catheter tube at the distal end of each;

introducing each inflated balloon and the distal end of the associated catheter tube together into the vessel, whereby clotting within the hollow interiors is prevented by the inflated balloons denying entry of blood into either catheter tube.