Method and apparatus for mapping a chamber of a heart

• US 6,368,285 B1
• Filed: 08/18/2000
• Issued: 04/09/2002
• Est. Priority Date: 09/21/1999
• Status: Expired due to Term

• Current Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Original Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Inventors: Reisfeld, Daniel, Osadchy, Margarita
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): Lin, Jeoyuh
• Application Number:
  US09/643,667
• Time in Patent Office: 599 Days
• Field of Search: 600/441, 600/409, 600/407, 600/508, 600/310, 600/342, 600/377, 600/374, 600/424, 600/425, 600/450, 600/463, 600/467, 600/468, 600/481, 600/483, 606/45, 606/130, 382/131, 382/173, 382/174
• US Class Current: 600/508
• CPC Class Codes: A61B 5/0064 Body surface scanning
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/062 using magnetic field
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies

Abstract

A method for intracardially mapping a condition such as an electrical or mechanical property of a chamber of a heart uses a catheter having a distal tip and at least one condition sensor contained therein or proximate thereto. The at least one sensor is capable of sensing condition information in the chamber and provides the three-dimensional position of the catheter tip in a positional frame of reference. The method includes the steps of acquiring first and second images of the chamber. The images are acquired from different projections and contain topological information of the chamber. The chamber images are registered with the positional frame of reference. The catheter distal tip is advanced into the catheter and is navigated to acquisition points under the guidance of topological information contained in or derived from the images. Condition and position information are acquired at each of the acquisition points, the points being sufficient in number and spacing to permit the generation of a map of the condition in the chamber. The topological information used to guide the navigation of the catheter is preferably a three-dimensional reconstruction of the chamber derived from the topological information contained in the images.

Claims

1. A method for intracardially mapping a condition of a chamber of a heart of a subject, said method comprising the steps of:

a) providing a catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a positional frame of reference;

b) acquiring a first image of said chamber, said first image taken from a first projection and containing topological information of said chamber;

c) acquiring a second image of said chamber, said second image taken from a second projection different from said first projection, said second image containing topological information of said chamber, and wherein said first projection and said second projection are separated by an angle of about 75 degrees to about 105 degrees.

d) registering said first image and said second image with said positional frame of reference;

e) advancing said distal tip of said catheter into said chamber;

f) navigating said distal tip of said catheter proximate an acquisition point in said chamber, said navigation guided by topological information contained in or derived from said first and said second images;

g) acquiring condition information and position information at said acquisition point with said at least one sensor;

h) repeating step (f) and (g) at additional acquisition points to generate a map of said condition in said chamber.

2. A method of mapping a chamber of a heart according to claim 1 wherein said condition is an electrical condition.

3. A method of mapping a chamber of a heart according to claim 1 wherein said condition is a mechanical condition.

4. A method of mapping a chamber of a heart according to claim 1 wherein said condition is an electromechanical condition.

5. A method of mapping a chamber of a heart according to claim 1 wherein said chamber is a left ventricle.

6. A method of mapping a chamber of a heart according to claim 1 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information, said position sensor further providing mechanical condition information.

7. A method of mapping a chamber of a heart according to claim 1 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

8. A method of mapping a chamber of a heart according to claim 1 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

9. A method of mapping a chamber of a heart according to claim 1 wherein said first and said second images of said chamber are contrast-assisted fluoroscopic images.

10. A method of mapping a chamber of a heart according to claim 1 wherein each of said first and said second images depict the chamber at the same phase of the cardiac cycle.

11. A method of mapping a chamber of a heart according to claim 10 wherein each of said first and said second images depict the chamber in end-diastole.

12. A method of mapping a chamber of a heart according to claim 1 wherein said topological information comprises the chamber contour.

13. A method of mapping a chamber of a heart according to claim 1 which further comprises acquiring an image of a scaling object from each of said first and said second projections.

14. A method of mapping a chamber of a heart according to claim 13 wherein said images of said scaling object are used to scale said images of said chamber.

15. A method of mapping a chamber of a heart according to claim 1 which further comprises affixing a registration position sensor to said patient prior to acquisition of said first and said second images of said chamber, wherein said chamber images include an image of said registration position sensor.

16. A method of mapping a chamber of a heart according to claim 15 which further comprises determining the three-dimension al position coordinates of said registration position sensor, and using said determined position coordinates to register said images of said chamber in said frame of reference.

17. A method of mapping a chamber of a heart according to claim 1 wherein said topological information used to guide said catheter tip to said acquisition points comprises a reconstruction of said chamber.

18. A method of mapping a chamber of a heart according to claim 17 wherein said reconstruction is a three-dimensional reconstruction.

19. A method of mapping a chamber of a heart according to claim 1 which further comprises the step of creating a map of said chamber from said acquired condition and position information.

20. A method for intracardially mapping a condition of a chamber of a heart of a subject, said method comprising the steps of:

a) providing a mapping catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a positional frame of reference;

b) providing a reconstruction of topological features of said chamber registered with said positional frame of reference, and wherein said reconstruction is based on;

i) a first image of said chamber taken from a first projection, and

ii) a second image of said chamber taken from a second projection, wherein each of said first and said second images contain topological information of said chamber, and wherein said first projection and said second projection are separated by an angle of about 75 degrees to about 105 degrees;

c) advancing said distal tip of said catheter into said chamber;

d) navigating said distal tip of said catheter proximate an acquisition point in said chamber, said navigation guided by said topological features of said reconstruction;

e) acquiring condition information and position information at said acquisition point with said at least one sensor;

f) repeating step (d) and (e) at additional acquisition points throughout the chamber to generate a map of said condition in said chamber.

21. A method of mapping a chamber of a heart according to claim 20 wherein said reconstruction is a three dimensional reconstruction.

22. A method of mapping a chamber of a heart according to claim 20 wherein said first and said second images of said chamber are contrast-assisted fluoroscopic images.

23. A method of mapping a chamber of a heart according to claim 20 wherein each of said first and said second images depict the chamber at the same phase of the cardiac cycle.

24. A method of mapping a chamber of a heart according to claim 20 wherein each of said first and said second images depict the chamber in end-diastole.

25. A method of mapping a chamber of a heart according to claim 20 wherein said topological information comprises the chamber contour.

26. A method of mapping a chamber of a heart according to claim 20 which further comprises acquiring an image of a scaling object from each of said first and said second projections.

27. A method of mapping a chamber of a heart according to claim 26 wherein said images of said scaling object are used to scale said images of said chamber.

28. A method of mapping a chamber of a heart according to claim 20 which further comprises affixing a registration position sensor to said patient prior to acquisition of said first and said second images of said chamber, wherein said chamber images include an image of said registration position sensor.

29. A method of mapping a chamber of a heart according to claim 28 which further comprises determining the three-dimensional position coordinates of said registration position sensor, and using said determined position coordinates to register said images of said chamber in said frame of reference.

30. A method of mapping a chamber of a heart according to claim 20 wherein said condition is an electrical condition.

31. A method of mapping a chamber of a heart according to claim 20 wherein said condition is a mechanical condition.

32. A method of mapping a chamber of a heart according to claim 20 wherein said condition is an electromechanical condition.

33. A method of mapping a chamber of a heart according to claim 20 wherein said chamber is a left ventricle.

34. A method of mapping a chamber of a heart according to claim 20 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information, said position sensor further providing mechanical condition information.

35. A method of mapping a chamber of a heart according to claim 20 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

36. A method of mapping a chamber of a heart according to claim 20 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

37. A method of mapping a chamber of a heart according to claim 20 which further comprises the step of creating a map of said chamber from said acquired condition and position information.

38. Apparatus for intracardially mapping a condition of a chamber of a heart of a subject comprising:

a) a catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a frame of reference;

b) image processing circuitry for registering a first image of said chamber and a second image of said chamber with said positional frame of reference, said first image and said second image taken from a first projection and a second projection relative to said chamber, said images containing topological information of said chamber, and wherein said first projection and said second projection are separated by an angle of about 75 degrees to about 105 degrees;

c) signal processing circuits for acquiring condition information and position information at a plurality of acquisition points in said chamber with said at least one sensor, said condition and position information permitting the generation of a map of said condition in said chamber.

39. Apparatus for mapping a chamber of a heart according to claim 38 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

40. Apparatus for mapping a chamber of a heart according to claim 38 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

41. Apparatus for mapping a chamber of a heart according to claim 38 which further comprises a scaling object.

42. Apparatus for mapping a chamber of a heart according to claim 38 which further comprises a registration position sensor to register said images with said frame of reference.

43. Apparatus for mapping a chamber of a heart according to claim 38 which further comprises image processing circuits for constructing a reconstruction of said chamber from said topological information contained in said images.

44. Apparatus for mapping a chamber of a heart according to claim 38 wherein said reconstruction is a three-dimensional reconstruction.

45. Apparatus for mapping a chamber of a heart according to claim 38 which further comprises circuits for mapping said condition of said chamber using said condition information and said position information.

46. Apparatus for intracardially mapping a condition of a chamber of a heart of a subject comprising:

a) a catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a frame of reference;

b) image processing circuits for constructing a topological reconstruction of said chamber registered with said frame of reference, said topological reconstruction including a first image of said chamber, said first image taken from a first projection and a second image of said chamber, said second image taken from a second projection different from said first projection, and wherein said first image and said second image are taken from an LAO projection and an RAO projection;

c) signal processing circuits for acquiring condition information and position information at a plurality of acquisition points in said chamber with said at least one sensor, said condition information and position information permitting the generation of a map of said condition in said chamber.

47. Apparatus for mapping a condition of a chamber of a heart of claim 46 wherein said reconstruction is a three dimensional reconstruction.

48. Apparatus for mapping a chamber of a heart according to claim 46 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

49. Apparatus for mapping a chamber of a heart according to claim 46 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

50. Apparatus for mapping a chamber of a heart according to claim 46 which further comprises a scaling object.

51. Apparatus for mapping a chamber of a heart according to claim 46 which further comprises a registration position sensor to register said images with said frame of reference.

70. A method of mapping a chamber of a heart according to claim 46 which further comprises the step of creating a map of said acquired condition and position information.

52. A method for intracardially mapping a condition of a chamber of a heart of a subject, said method comprising the steps of:

a) providing a catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a positional frame of reference;

b) acquiring a first image of said chamber, said first image taken from a first projection and containing topological information of said chamber;

c) acquiring a second image of said chamber, said second image taken from a second projection different from said first projection, said second image containing topological information of said chamber, and wherein said first image and said second image are taken from an LAO projection and an RAO projection;

d) registering said first image and said second image with said positional frame of reference;

e) advancing said distal tip of said catheter into said chamber;

f) navigating said distal tip of said catheter proximate an acquisition point in said chamber, said navigation guided by topological information contained in or derived from said first and second images;

g) acquiring condition information and position information at said acquisition point with said at least one sensor;

h) repeating step (f) and (g) at additional acquisition points to generate a map of said condition in said chamber.

53. A method of mapping a chamber of a heart according to claim 52 wherein said condition is an electrical condition.

54. A method of mapping a chamber of a heart according to claim 52 wherein said condition is a mechanical condition.

55. A method of mapping a chamber of a heart according to claim 52 wherein said condition is an electromechanical condition.

56. A method of mapping a chamber of a heart according to claim 52 wherein said chamber is a left ventricle.

57. A method of mapping a chamber of a heart according to claim 52 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information, said position sensor further providing mechanical condition information.

58. A method of mapping a chamber of a heart according to claim 52 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

59. A method of mapping a chamber of a heart according to claim 52 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

60. A method of mapping a chamber of a heart according to claim 52 wherein said first and said second images of said chamber are contrast-assisted fluoroscopic images.

61. A method of mapping a chamber of a heart according to claim 52 wherein each of said first and second images depict the chamber at the same phase of the cardiac cycle.

62. A method of mapping a chamber of a heart according to claim 61 wherein each of said first and said second images depict the chamber in end-diastole.

63. A method of mapping a chamber of a heart according to claim 52 wherein said topological information comprises the chamber contour.

64. A method of mapping a chamber of a heart according to claim 52 which further comprises acquiring an image of a scaling object from each said first and said second projections.

65. A method of mapping a chamber of a heart according to claim 64 wherein said images of said scaling object are used to scale said images of said chamber.

66. A method of mapping a chamber of a heart according to claim 52 which further comprises affixing a registration position sensor to said patient prior to acquisition of said first and said second images of said chamber, wherein said chamber images include an image of said registration position sensor.

67. A method of mapping a chamber of a heart according to claim 66 which further comprises determining the three-dimensional position coordinates of said registration position sensor, and using said determined position coordinates to register said images of said chamber in said frame of reference.

68. A method of mapping a chamber of a heart according to claim 52 wherein said topological information used to guide said catheter tip to said acquisition points comprises a reconstruction of said chamber.

69. A method of mapping a chamber of a heart according to claim 68 wherein said reconstruction is a three-dimensional reconstruction.

71. A method for intracardially mapping a condition of a chamber of a heart of a subject, said method comprising the steps of:

a) providing a mapping catheter having a distal tip, said catheter distal tip having at least one sensor contained therein or proximate thereto, said at least one sensor being capable of sensing condition information of said chamber and providing three-dimensional position information of the catheter tip in a positional frame of reference;

b) providing a reconstruction of topological features of said chamber registered with said positional frame of reference, and wherein said reconstruction is based on;

i) a first image of said chamber taken from a first projection, and

ii) a second image of said chamber taken from a second projection, wherein each of said first and said second images contain topological information of said chamber, and wherein said first image and said second image are taken from an LAO projection and an RAO projection;

c) advancing said distal tip of said catheter into said chamber;

d) navigating said distal tip of said catheter proximate an acquisition point in said chamber, said navigation guided by said topological features of said reconstruction;

e) acquiring condition information and position information at said acquisition point with said at least one sensor;

f) repeating step (d) and (e) at additional acquisition points throughout the chamber to generate a map of said chamber.

72. A method of mapping a chamber of a heart according to claim 71 wherein said reconstruction is a three-dimensional reconstruction.

73. A method of mapping a chamber of a heart according to claim 71 wherein said first and said second images of said chamber are contrast-assisted fluoroscopic images.

74. A method of mapping a chamber of a heart according to claim 71 wherein each of said first and said second images depict the chamber at the same phase of the cardiac cycle.

75. A method of mapping a chamber of a heart according to claim 71 wherein each of said first and said second images depict the chamber in end-diastole.

76. A method of mapping a chamber of a heart according to claim 71 wherein said topological information comprises the chamber contour.

77. A method of mapping a chamber of a heart according to claim 71 which further comprises acquiring an image of a scaling object from each of said first and said second projections.

78. A method of mapping a chamber of a heart according to claim 77 wherein said images of said scaling object are used to scale said images of said chamber.

79. A method of mapping a chamber of a heart according to claim 71 which further comprises affixing a registration position sensor to said patient prior to acquisition of said first and said second images of said chamber, wherein said chamber images include an image of said registration position sensor.

80. A method of mapping a chamber of a heart according to claim 79 which further comprises determining the three-dimensional position coordinates of said registration position sensor, and using said determined position coordinates to register said images of said chamber in said frame of reference.

81. A method of mapping a chamber of a heart according to claim 71 wherein said condition is an electrical condition.

82. A method of mapping a chamber of a heart according to claim 71 wherein said condition is a mechanical condition.

83. A method of mapping a chamber of a heart according to claim 71 wherein said condition is an electromechanical condition.

84. A method of mapping a chamber of a heart according to claim 71 wherein said chamber is a left ventricle.

85. A method of mapping a chamber of a heart according to claim 71 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information, said position further providing mechanical condition information.

86. A method of mapping a chamber of a heart according to claim 71 wherein said at least one sensor comprises a position sensor capable of providing said three-dimensional position information and an electrode for sensing electrical information.

87. A method of mapping a chamber of a heart according to claim 71 wherein said at least one sensor comprises an electromagnetic sensor, said electromagnetic sensor generating signals responsive to the strength of a magnetic field external to the patient, said signals indicative of the three-dimensional position of the sensor in said frame of reference.

88. A method of mapping a chamber of a heart according to claim 71 which further comprises the step of creating a map of said chamber from said acquired condition and position information.