Inflatable neural prosthesis

• US 6,368,349 B1
• Filed: 11/21/2000
• Issued: 04/09/2002
• Est. Priority Date: 11/21/2000
• Status: Expired due to Fees

• Current Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Original Assignee: Massachusetts Institute of Technology
• Inventors: Wyatt, John, Rizzo, Joseph, Shire, Doug
• Primary Examiner(s): McDermott, Corrine
• Assistant Examiner(s): BARRETT, THOMAS C
• Application Number:
  US09/717,738
• Time in Patent Office: 504 Days
• Field of Search: 623/1-- 6, 607/54
• US Class Current: 623/6.63
• CPC Class Codes: A61F 2/14 Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

Neural prosthesis for implantation within an eye. The prosthesis includes a foldable substrate and at least one electronic component supported by the substrate. At least one microchannel is disposed within the substrate. Upon inflation, the foldable substrate will unfold to provide for close contact of the electronic component with neural tissue, thus facilitating surgical implantation through a narrow incision, yet allowing the unfolded device to cover a sufficiently large portion of the patient'"'"'s retina to provide useful vision.

Claims

1. Neural prosthesis comprising:

a foldable substrate;

at least one electronic component supported by the substrate; and

at least one microchannel disposed within the substrate for expanding the substrate.

2. The neural prosthesis of claim 1 wherein the electronic component is an integrated circuit.

3. The neural prosthesis of claim 1 wherein the electronic component is an electrode array.

4. The neural prosthesis of claim 3 wherein the foldable substrate in an expanded state provides close apposition between the electrode array and neural tissue within the eye.

5. The neural prosthesis of claim 1 wherein the substrate includes a central region surrounded by projecting structures, each of the projecting structures including the microchannel.

6. The neural prosthesis of claim 5 wherein the projecting structures include an electrode array for stimulating neural tissue.

7. The neural prosthesis of claim 5 wherein the central region comprises silicon and the projecting structures comprise a flexible insulating polymer.

8. The neural prosthesis of claim 3 wherein the electrode array includes activated iridium electrodes.

9. The neural prosthesis of claim 5 wherein the central region includes structure for attaching a source of pressurized gas or fluid for inflating the prosthesis.

10. The neural prosthesis of claim 9 wherein the source of pressurized gas or fluid includes means for altering the position of the prosthesis.

11. The neural prosthesis of claim 9 wherein the source of pressurized gas or fluid includes means for altering the degree of inflation of the prosthesis.

12. The neural prosthesis of claim 1 wherein the foldable substrate includes structure for attaching a source of pressurized gas or fluid for inflating the prosthesis.

13. The neural prosthesis of claim 1 wherein the substrate includes multiple foldable sections.