Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
First Claim
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1. A process for preparing a solid formulation of a fibrate having more rapid dissolution comprising the steps of:
- forming a mixture of said fibrate with a surfactant;
granulating said mixture by melting, mixing, and congealing said fibrate and said surfactant, optionally with one or more excipients;
and optionally forming a finished dosage form.
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Abstract
A process for preparing a solid formulation of a lipid-regulating agent comprising forming a mixture of said lipid-regulating agent with a surfactant; granulating said mixture by melting, mixing, and congealing said mixture; and optionally forming a finished dosage form.
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Citations
15 Claims
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1. A process for preparing a solid formulation of a fibrate having more rapid dissolution comprising the steps of:
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forming a mixture of said fibrate with a surfactant;
granulating said mixture by melting, mixing, and congealing said fibrate and said surfactant, optionally with one or more excipients;
and optionally forming a finished dosage form. - View Dependent Claims (4, 5, 6, 7, 8, 9, 11, 12, 14)
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2. A process for preparing a solid formulation of a fibrate comprising the steps of:
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forming a mixture of said fibrate with a surfactant;
granulating said mixture by melting, mixing, and congealing, optionally with one or more excipients;
and optionally forming a finished dosage form. - View Dependent Claims (3, 13, 15)
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10. A process for preparing a solid formulation of a fibrate having more rapid dissolution comprising the steps of:
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forming a mixture of said fibrate with a surfactant;
granulating said mixture by melting, mixing, and congealing, said fibrate and said surfactant, optionally with one or more excipients;
and forming a tablet.
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Specification