Method and manufacture of a wound dressing for covering an open wound

• US 6,369,289 B1
• Filed: 07/07/2000
• Issued: 04/09/2002
• Est. Priority Date: 07/07/2000
• Status: Expired due to Term

• Current Assignee: Kpr U.S., LLC (Cardinal Health, Inc.)
• Original Assignee: Tyco Healthcare Group LP (Medtronic Plc)
• Inventors: Orr, Robert H. III
• Primary Examiner(s): Lewis, Kim M.
• Application Number:
  US09/611,482
• Time in Patent Office: 641 Days
• Field of Search: 602/41-59, 128/888, 128/889, 424/78.08, 424/78.26, 424/78.34, 424/78.35, 424/404-407, 424/409, 424/411
• US Class Current: 602/48
• CPC Class Codes: A61F 13/00063 comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic drug delivery dressings A61K9/70; chemical aspect of the additives A61L15/00
• CPC Class Codes: A61F 13/00995 for mechanical treatments
• CPC Class Codes: A61F 13/01012 being made of natural material, e.g. cellulose-, protein-, collagen-based
• CPC Class Codes: A61F 13/0263 especially adapted for island dressings
• CPC Class Codes: A61F 2013/0091 with disinfecting or anaesthetics means, e.g. anti-mycrobic
• CPC Class Codes: A61L 15/28 Polysaccharides or their derivatives A61L15/225 takes precedence
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 2300/206 Biguanides, e.g. chlorohexidine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: C08L 1/02 Cellulose; Modified cellulose
• CPC Class Codes: D06M 15/59 Polyamides; Polyimides
• CPC Class Codes: D06M 16/00 Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
• CPC Class Codes: D06M 2101/06 cellulosic

Abstract

A method for covering an open wound by contacting the wound with a cellulosic bandage having a calculated amount of PHMB applied to the bandage. The cellulosic bandage can be prepared by providing at least one rolled beam of cellulosic material onto a perforated drum, inserting the beam of material into an enclosed vessel, adding PHMB into the vessel, and circulating the PHMB for a predetermined period of time.

Claims

1. A method of covering an open wound, comprising the step of contacting a wound with a cellulosic bandage consisting essentially of an antimicrobial amount of PHMB applied to the bandage.

2. The method of claim 1, further comprising the step of directly contacting the open wound with the cellulosic bandage without requiring an intermediate layer.

3. The method of claim 1, wherein the antimicrobial amount of PHMB applied to the bandage is between 1500-2500 ppm.

4. The method of claim 1, wherein the cellulosic bandage is between 50% to 100% cellulosic.

5. The method of claim 1, wherein the cellulosic bandage is an island dressing.

6. The method of claim 1, wherein the cellulosic bandage is a sponge.

7. The method of claim 1, wherein the cellulosic bandage is a roll bandage.

8. A method of manufacturing a wound dressing having antimicrobial properties, comprising the steps of:

A) providing at least one rolled beam of cellulosic material;

B) inserting the beam of material into an enclosed vessel;

C) adding PHMB into the vessel, wherein the volume of PHMB added to the vessel is between 0.10% and 0.80% of the total water volume; and

D) circulating the PHMB for a predetermined period of time.

9. The method of claim 8, wherein the at least one beam of material is rolled onto a perforated drum and the PHMB is added into the vessel through the perforated drum.

10. The method of claim 9, further comprising the step of bleaching the beam of material before said step of adding PHMB into the vessel.

11. The method of claim 10, wherein said bleaching step is performed by pumping bleaching agents into the vessel through the perforated drum.

12. The method of claim 10, further comprising the step of chemically rinsing the beam of material after said bleaching step and before said step of adding PHMB into the vessel.

13. The method of claim 12, further comprising the step of filling the enclosed vessel with water after said rinsing step and prior to said step of adding PHMB into the vessel.

14. The method of claim 8, wherein said circulating step is performed for approximately between 15 and 45 minutes.

15. The method of claim 14, wherein said circulating step is performed for approximately 30 minutes.

16. The method of claim 15, wherein the volume of PHMB added to the vessel during said step of adding PHMB is approximately 0.67% of the total water volume.

17. The method of claim 8, further comprising the step of draining the wastewater into a plant waste water system.

18. The method of claim 8, further comprising the steps of:

A) removing the beams of material from the enclosed vessel; and

B) unwinding the material for further processing.

19. The method of claim 8, wherein said step of circulating the PHMB is caused by directing the PHMB through the perforated drum and in a direction radially outwardly.

20. A product manufactured according to the method of claim 8.

21. A cellulosic wound dressing consisting essentially of an antimicrobial amount of PHMB.

22. The wound dressing of claim 21, wherein the antimicrobial amount of PHMB applied to the bandage is between 1500-2500 ppm.

23. The wound dressing of claim 21, wherein the cellulosic bandage is between 50% to 100% cellulosic.

24. The wound dressing of claim 21, wherein the cellulosic bandage is an island dressing.

25. The wound dressing of claim 21, wherein the cellulosic bandage is a sponge.

26. The wound dressing of claim 21, wherein the cellulosic bandage is a roll bandage.