Non-invasive cardiorespiratory monitor with synchronized bioimpedance sensing

• US 6,370,424 B1
• Filed: 12/14/1999
• Issued: 04/09/2002
• Est. Priority Date: 02/06/1998
• Status: Expired due to Term

• Current Assignee: Intermedics Incorporated
• Original Assignee: Intermedics Incorporated
• Inventors: Prutchi, David
• Primary Examiner(s): Nasser, Robert L.
• Assistant Examiner(s): Natnithithadha, Navin
• Application Number:
  US09/460,744
• Time in Patent Office: 847 Days
• Field of Search: 600/536, 600/547, 600/506, 600/533, 607/9, 607/6, 607/20, 607/17, 607/27, 607/32
• US Class Current: 600/547
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/4869 Determining body composition

Abstract

A cardiorespiratory monitor that generates bioimpedance sensing signals that produce substantially no interference with bioimpedance signals generated by implanted devices. The monitor detects the bioimpedance signal generated by the implanted device, using a voltage detector or a telemetry circuit, for example. The monitor analyzes this detected signal to generate a bioimpedance sensing signal that will not interfere with the sensed signal. For instance, if the monitor produces a pulsed sensing signal, the pulses are delivered in an interval of the detected signal where no pulses are present. Similarly, if the monitor produces a high frequency AC sensing signal, the zero crossings of the AC sensing signal are positioned during the delivery of a pulse by the implanted device.

Claims

1. A device, comprising:

means for detecting pulses generated by an implanted device; and

means for sensing impedance in a torso between the pulses generated by the implanted device.

2. The device of claim 1, wherein the detecting means includes means for communicating with the implanted device.

3. The device of claim 1, wherein the sensing means includes means for generating a pulsed bioimpedance sensing signal between the pulses generated by the implanted device.

4. The device of claim 1, wherein the sensing means includes means for generating a high frequency AC bioimpedance sensing signal between the pulses generated by the implanted device.

5. A device, comprising:

a pulse detector, where the pulse detector is adapted to detect pulses from an impedance sensor of an implantable device;

a processing circuit coupled to the pulse detector, where the processing circuit analyzes the detected pulses to determine parameters of the detected pulses and to calculate a sampling interval based on the parameters; and

a current injection and sampling circuit, where the current injection and sampling circuit injects current pulses at the sampling interval in synchronization with the pulses from the impedance sensor of the implantable device.

6. The device of claim 5, where the pulse detector includes a telemetry circuit which is adapted to receive a timing interval of the pulses from a telemetry circuit of the implantable device.

7. The device of claim 5, where the pulse detector includes one or more electrodes for detecting the pulses from the implanted device.

8. The device of claim 5, where the pulse detector is an AC-coupled comparator which is adapted to capture a beginning and an end of each pulse generated by the implantable device.

9. The device of claim 5, where the parameters determined by the processing circuit include a frequency, a timing and a duration of the detected pulses.

10. The device of claim 5, where the sampling interval is between successive pulses from the implanted device.

11. The device of claim 5, including a synchronous voltage sensor coupled to the processing circuit, where the synchronous voltage sensor monitors the current pulses from the current injection and sampling circuit.

12. The device of claim 11, where the processing circuit receives an ECG signal, and where the processing circuit processes the impedance signal and the ECG signal to produce indications of cardiorespiratory function.

13. The device of claim 12, including a display screen coupled to the processing circuit, where the processing circuit displays the indications of cardiorespiratory function on the display screen.

14. The device of claim 12, where indications of cardiorespiratory function include heart rate, stroke volume, cardiac output and/or minute ventilation.

15. A method, comprising:

detecting an impedance signal with an implantable device;

detecting pulses in the impedance signal;

analyzing the detected pulses to determine parameters of the detected pulses;

calculating a sampling interval based on the parameters; and

delivering current pulses at the sampling interval in synchronization with the pulses from the impedance sensor of the implantable device.

16. The method of claim 15, including receiving a timing interval of the pulses as a parameter from a telemetry circuit of the implantable device.

17. The method of claim 15, where delivering current pulses at the sampling interval includes delivering each current pulse of the current pulses between successive pulses from the implanted device.

18. The method of claim 15, which includes sensing an ECG signal;

and

processing the impedance signal and the ECG signal to produce indications of cardiorespiratory function.

19. The method of claim 18, which includes displaying the indications of cardiorespiratory function on a display screen.

20. The method of claim 18, which includes displaying heart rate, stroke volume, cardiac output and/or minute ventilation as the indications of cardiorespiratory function on a display screen.