Autoinjector

• US 6,371,939 B2
• Filed: 01/24/2001
• Issued: 04/16/2002
• Est. Priority Date: 10/26/1998
• Status: Expired due to Term

• Current Assignee: Shl Medical AG
• Original Assignee: Pharmacia AB (Pharmacia Corp.)
• Inventors: Bergens, Thomas, Amark, Mikael
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US09/768,761
• Publication Number:
  US 20010005781A1
• Time in Patent Office: 447 Days
• Field of Search: 604/131, 604/154, 604/95.01, 604/95.02, 604/110, 604/130, 604/132, 604/133, 604/134, 604/135, 604/136, 604/138, 604/139, 604/156-158, 604/192-196, 604/198, 604/199, 604/218, 604/232, 606/172, 606/182, 128/DIG.1, 128/DIG.12, 128/DIG.13
• US Class Current: 604/156
• CPC Class Codes: A61M 2005/202 cocking means, e.g. to bias the main drive spring of an injector
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2086 having piston damping means, e.g. axially or rotationally acting retarders
• CPC Class Codes: A61M 2005/2418 comprising means for damping shocks on ampoule
• CPC Class Codes: A61M 2005/3143 Damping means for syringe components executing relative movements, e.g. retarders or attenuators slowing down or timing syringe mechanisms
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An autoinjector for replaceable containers of syringe type, comprising a barrel of axially roughly constant cross-section, a front opening with or for an injection needle and at least one movable rear piston, optionally with a plunger connected thereto, inserted in the barrel for the displacement of a container content, the autoinjector comprising a) a housing, b) a container carrier, arranged for reception of the container and arranged movably in relation to the housing in container axial direction between a rear, needle-covering, position and a forward, needle-exposing, position, c) an autopenetration mechanism, comprising at least a penetration head and a penetration drive, the penetration head being arranged for movement of the barrel or carrier in the forward direction and the penetration drive being operable to apply force between the housing and the penetration head, d) an autoinjection mechanism, comprising at least an injection head and an injection drive, the injection head being arranged for movement of the piston or plunger in the forward direction and the injection drive being operable to apply force between the housing or the carrier and the injection head, e) optionally an autoreturn mechanism operable to apply force between the housing and the barrel or carrier for movement thereof in the rearward direction and f) a control system for sequencing the operation of at least the autopenetration and autoinjection mechanisms, at least comprising a releasable penetration lock for the autopenetration mechanism and a releasable injection lock for the autoinjection mechanism. The carrier is designed to accommodate either of at least two containers of different length and/or width and at least one damper arranged for energy absorption from the autopenetration and/or autoinjection movement.

Claims

1. An autoinjector for replaceable syringe containers comprising a barrel, a front opening with or for an injection needle and at least one movable rear piston, optionally with a plunger connected thereto, inserted in the barrel for the displacement of a container content, the autoinjector comprising

a) a housing,

b) a container carrier, arranged for reception of a container and arranged movably in relation to the housing in a container axial direction between a rear, needle-covering position and a forward, needle-exposing, position,

c) an autopenetration mechanism comprising at least a penetration head and penetration drive, the penetration head being arranged for movement of the barrel or carrier in the forward direction and the penetration drive being operable to apply force between the housing and the penetration head;

d) an autoinjection mechanism comprising at least an injection head and an injection drive, the injection head being arranged for movement of a piston or plunger in the forward direction about the injection drive being operable to apply force between the housing of the carrier and the injection head,

e) optionally an autoreturn mechanism operable to apply force between the housing and the barrel or carrier for movement thereof in the rearward direction,

f) a control system for sequencing the operation of at least the autopenetration and autoinjection mechanism and a releasable injection lock for the autoinjection mechanism, and

g) at least one damper arranged for energy absorption from the autopenetration and/or autoinjection movement.

2. The autoinjector of claim 1, wherein the damper is included in the penetration head.

3. The autoinjector of claim 2, wherein the damper includes a spring arranged in the axial direction, and further wherein the spring force is weaker than the force of the penetration drive.

4. The autoinjector of claim 3, wherein the penetration head comprises at least two parts between which the spring is arranged.

5. The autoinjector of claim 4, wherein the control system is arranged to enable the autoinjectin mechanism at relative movement between the two parts of the penetration head.

6. The autoinjector of claim 1, wherein the damper is included in the injection head.

7. The autoinjector of claim 6, wherein at least a part of the injection head is resilient and is operable as a damper.

8. The autoinjector of claim 1, wherein the damper is a viscous damper arranged to retard the autoinjection movement.

9. The autoinjector of claim 8, wherein the viscous damper retardation dominates over syringe flow restrictions.

10. The autoinjector of claim 8, wherein the autopenetration movement is unretarded or is at least less retarded than the autoinjection movement.

11. The autoinjector of claim 8, wherein the viscous damper is connected, directly or indirectly, between the penetration head and the injection head, to act at relative motions therebetween.

12. The autoinjector of claim 8, wherein the viscous damper is arranged in parallel with the injection head movement.

13. The autoinjector of claim 8, wherein the penetration drive is separate from, and provides a less strong force than, the injection drive.