Vaso-occlusive member assembly with multiple detaching points

• US 6,371,972 B1
• Filed: 09/15/2000
• Issued: 04/16/2002
• Est. Priority Date: 02/18/1998
• Status: Expired due to Term

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Inventors: Wallace, Michael P., Roue, Chad C.
• Primary Examiner(s): Smith, Jeffrey A.
• Assistant Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/662,981
• Time in Patent Office: 578 Days
• Field of Search: A61/B 1.700, A61/B 1.708, A61/B 1.738, 606/32, 606/41, 606/49, 606/28, 606/108, 606/191, 606/200
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12163 having a string of elements connected to each other
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12063 electrolytically detachable

Abstract

This device is an apparatus for endovascular occlusion through the formation of thrombi in arteries, veins, aneurysms, vascular malformations, and arteriovenous fistulas. In particular, the device includes multiple vaso-occlusive members connected by electrolytically disintegratible links. Each link connects to the vaso-occlusive member by electrically insulative and conductive joints on opposite ends of the link. The vaso-occlusive members are delivered through a delivery catheter having on its distal end an electrode for electrical contact with the vaso-occlusive member. Upon application of an electrical current through the electrode to the vaso-occlusive member and its conductive joint to the electrolytically disintegratible link, the link disintegrates, selectively detaching the desired number of vaso-occlusive members into the target thrombus formation site.

Claims

1. An assembly for use in the formation of an occlusion comprising:

an occlusive member having a proximal end,

an insulative joint located proximally on said occlusive member,

an electrolytically disintegratible link located proximally of said insulative joint, and

a conductive joint located proximally on said electrolytically disintegratible link, said joint configured for connection to an additional occlusive member.

2. The assembly of claim 1 wherein said link is coated with an insulative layer containing a groove, said groove exposing said underlying link.

3. The assembly of claim 2 wherein said insulative layer comprises a polymer.

4. The assembly of claim 3 wherein said groove is produced by laser scoring.

5. The assembly of claim 1 wherein said occlusive member comprises a coil.

6. The assembly of claim 1 wherein said insulative joint comprises an insulative layer.

7. The assembly of claim 1 wherein the insulative joint comprises an electrically insulative biocompatible adhesive.

8. An assembly for use in the formation of an occlusion comprising:

a vaso-occlusive member having a proximal end and a distal end,

an insulative joint disposed on said proximal end of said vaso-occlusive member, and

a conductive joint disposed on said distal end of said vaso-occlusive member.

9. The vaso-occlusive member of claim 8 additionally comprising an electrolytically disintegratible link located proximally of said insulative joint.

10. The assembly of claim 9 wherein said link is coated with an insulative layer containing a groove, said groove exposing said underlying link.

11. The assembly of claim 10 wherein said insulative layer comprises a polymer.

12. The assembly of claim 11 wherein said groove is produced by laser scoring.

13. The vaso-occlusive member of claim 8 wherein said vaso-occlusive member is a coil.

14. The assembly of claim 8 wherein the insulative joint comprises an electrically insulative biocompatible adhesive.

15. A method for occluding a body cavity, comprising:

disposing an assembly at least partially into said body cavity,

said assembly comprising (i) a wire having a first insulative joint attached to a distal end of said wire, a first vaso-occlusive member attached to said first insulative joint, and (ii) at least one section comprising (1) a conductive joint attached to said first vaso-occlusive member, (2) an electrolytically disintegratible link having a proximal end attached to said conductive joint and a distal end attached to an additional insulative joint, and (3) an additional vaso-occlusive member attached to said additional insulative joint, and

electrolytically disintegrating said link to leave at least a portion of said assembly within said body cavity.

16. The method of claim 15 further comprising the step of repeating said steps of disposing said assembly at least partially into said body cavity and electrolytically disintegrating said link to leave a plurality of portions of said assembly within said body cavity.

17. The method of claim 15 wherein said assembly is disposed at least partially into said body cavity through a catheter distal end, said catheter having a distal electrode.

18. The method of claim 17 wherein said catheter additionally comprises a radiopaque marker.

19. The method of claim 15 additionally comprising the step of applying a positive electric current to said assembly prior to electrolytically disintegrating said link to form a thrombus within said body cavity.

20. The method of claim 15 wherein said body cavity comprises an aneurysm.