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Polyethylene glycol coating for electrostatic dry deposition of pharmaceuticals

  • US 6,372,246 B1
  • Filed: 12/16/1998
  • Issued: 04/16/2002
  • Est. Priority Date: 12/16/1998
  • Status: Expired due to Term
First Claim
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1. A pharmaceutical composition comprising an edible substrate having micronized drug substance with a particle size of 1-100 μ

  • m deposited on the surface of the substrate by electrostatic dry powder deposition, and a film coating on the substrate and drug substance consisting essentially of polyethylene glycol, wherein the film coating is applied by;

    (a) coating the substrate in place by electrostatic dry powder deposition with dry micronized polyethylene glycol having a molecular weight in the range of 1,000 to 20,000 and having a particle size of 1-100 μ

    m, and (b) melting the dry polyethylene glycol coating and allowing it to cool whereupon a protective coating is formed.

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