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Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof

  • US 6,375,972 B1
  • Filed: 04/26/2000
  • Issued: 04/23/2002
  • Est. Priority Date: 04/26/2000
  • Status: Expired due to Term
First Claim
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1. A sustained release drug delivery system comprising:

  • an inner drug core comprising a therapeutically effective amount of an agent effective in obtaining a desired local or systemic physiological or pharmacological effect;

    an inner tube impermeable to the passage of said agent, said inner tube having first and second ends and covering at least a portion of said inner drug core, said inner tube sized and formed of a material so that said inner tube is dimensionally stable to accept said drug core without changing shape;

    an impermeable member positioned at said inner tube first end, said impermeable member preventing passage of said agent out of said drug core through said inner tube first end; and

    a permeable member positioned at said inner tube second end, said permeable member allowing diffusion of said agent out of said drug core through said inner tube second end.

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