Medical device for selective intrathecal spinal cooling in aortic surgery and spinal trauma
First Claim
1. A method for preventing neurologic damage, comprising the steps of:
- providing first and second elongate tubular members, each member having a lumen communicating with a port at a distal end;
inserting the first tubular member between lumbar vertebrae into the subarachnoid space;
inserting the second tubular member between lumbar vertebrae into the subarachnoid space, and advancing the distal port cephalad and locating the port in the cervical or thoracic region of the spine;
aspirating or draining cerebral spinal fluid (CSF) from the spinal column through one of the first tubular member or second tubular member;
cooling the CSF by extracorporeal refrigeration; and
perfusing the CSF into the spinal column through the other of the first tubular member or second tubular member, wherein the spinal cord is cooled to below normal body temperature, and wherein CSF pressure is reduced to and maintained at a level substantially below normal CSF pressure.
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Accused Products
Abstract
The invention provides a medical device having two elongate catheters, a pump, a refrigeration system, and a manometer. Each catheter has a proximal end, a distal end, a lumen therebetween and communicating with a distal port. The proximal ends of the catheters are connected to the pump and the refrigeration system. The distal ends are adapted for insertion into the subarachnoid space. The cerebral spinal fluid is aspirated from the first catheter to the pump, cooled to below body temperature, and returned to the second catheter. The flow rate of the cerebral spinal fluid is adjusted according the CSF pressure and temperature. Methods of using the devices in treating patients suffering from spinal trauma and undergoing aortic surgery are also disclosed.
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Citations
35 Claims
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1. A method for preventing neurologic damage, comprising the steps of:
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providing first and second elongate tubular members, each member having a lumen communicating with a port at a distal end;
inserting the first tubular member between lumbar vertebrae into the subarachnoid space;
inserting the second tubular member between lumbar vertebrae into the subarachnoid space, and advancing the distal port cephalad and locating the port in the cervical or thoracic region of the spine;
aspirating or draining cerebral spinal fluid (CSF) from the spinal column through one of the first tubular member or second tubular member;
cooling the CSF by extracorporeal refrigeration; and
perfusing the CSF into the spinal column through the other of the first tubular member or second tubular member, wherein the spinal cord is cooled to below normal body temperature, and wherein CSF pressure is reduced to and maintained at a level substantially below normal CSF pressure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 23)
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12. A method for preventing neurologic damage, comprising the steps of:
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providing first and second elongate tubular members, each member having a lumen communicating with a port at a distal end;
inserting the first tubular member between lumbar vertebrae into the subarachnoid space;
inserting the second tubular member between low cervical vertebrae into the subarachnoid space, and advancing the distal port cephalad or caudal and locating the port in the cervical, thoracic, or lumbar region of the spine;
aspirating cerebral spinal fluid (CSF) from the spinal column through one of the first tubular member or second tubular member;
cooling the CSF by extracorporeal refrigeration; and
perfusing the CSF into the spinal column through the other of the first tubular member or second tubular member, wherein the spinal cord is cooled to below normal body temperature and wherein CSF pressure is reduced to and maintained at a level substantially below normal CSF pressure. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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24. A method for treating stroke, comprising the steps of:
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providing first and second elongate tubular members, each member having a lumen communicating with a port at a distal end;
inserting the first tubular member between lumbar vertebrae into the subarachnoid space;
inserting the second tubular member between lumbar vertebrae into the subarachnoid space, and advancing the distal port cephalad and locating the port in the cervical or thoracic region of the spine;
aspirating or draining cerebral spinal fluid (CSF) from the spinal column through one of the first tubular member or second tubular member;
perfusing the CSF into the spinal column through the other of the first tubular member or second tubular member, wherein CSF pressure is reduced to and maintained at a level substantially below normal CSF pressure; and
injecting one or more pharmaceutical agents through the other of the first tubular member or second tubular member. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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Specification