Metal stent containing radioactivatable isotope and method of making same
First Claim
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1. A medical procedure, which comprises:
- (a) selecting a generally tubularly-shaped stent of a biocompatible metal of a substantially uniform dispersion of from about 0.05 to about 10.00 percent by weight of an enriched radioactivatable isotope having a half-life of less than two months and principally a beta particle emitter;
(b) radioactivating said stent to a dosage of radiation; and
(c) implanting said radioactivated stent within inner lumens of a cardiovascular passageway to engage said inner lumens of said cardiovascular passageway thereby to provide support against collapse of said cardiovascular passageway and to provide radiation therapy.
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Abstract
A metal stent for vascular implantation comprising a generally tubular structure whose extend surface is adapted to engage the interior vascular surface when implanted, said metal of said stent containing a substantially uniform dispersion of from about 0.05 to about 10.00 percent by weight of one or more naturally occurring or enriched stable isotopes having a half-life of less than two months and that are principally beta particle emitters, so that when activated, said stent emits low to moderate dosages of radiation uniformly to reduce cell proliferation.
116 Citations
7 Claims
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1. A medical procedure, which comprises:
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(a) selecting a generally tubularly-shaped stent of a biocompatible metal of a substantially uniform dispersion of from about 0.05 to about 10.00 percent by weight of an enriched radioactivatable isotope having a half-life of less than two months and principally a beta particle emitter;
(b) radioactivating said stent to a dosage of radiation; and
(c) implanting said radioactivated stent within inner lumens of a cardiovascular passageway to engage said inner lumens of said cardiovascular passageway thereby to provide support against collapse of said cardiovascular passageway and to provide radiation therapy. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification