Controlled release of metal cation-stabilized interferon
First Claim
1. A composition for the controlled release of interferon from a polymeric matrix, comprising:
- a) a biocompatible polymer; and
b) particles of metal cation-complexed interferon, with a metal cation-to-interferon molar ratio between about 1;
1 and 10;
1, wherein said particles are dispersed within the biocompatible polymer.
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Abstract
This invention relates to a composition, and method of forming said composition, for the controlled release of interferon. The controlled release composition of this invention comprises a biocompatible polymer and particles of metal cation-stabilized interferon, wherein the particles are dispersed within the biocompatible polymer.
The method of the invention, for producing a composition for the controlled release of interferon, includes dissolving a polymer in a polymer solvent to form a polymer solution, dispersing particles of metal cation stabilized-interferon particles in the polymer solution, and then solidifying the polymer to form a polymeric matrix containing a dispersion of the interferon particles.
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Citations
10 Claims
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1. A composition for the controlled release of interferon from a polymeric matrix, comprising:
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a) a biocompatible polymer; and
b) particles of metal cation-complexed interferon, with a metal cation-to-interferon molar ratio between about 1;
1 and 10;
1, wherein said particles are dispersed within the biocompatible polymer.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification