Sheath for tissue spectroscopy

• US 6,383,209 B1
• Filed: 06/01/2000
• Issued: 05/07/2002
• Est. Priority Date: 09/29/1997
• Status: Expired due to Term

• Current Assignee: Boston Scientific Corporation
• Original Assignee: Boston Scientific Corporation
• Inventors: Crowley, Robert J.
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/585,188
• Time in Patent Office: 705 Days
• Field of Search: 607/88-89, 606/15-17, 600/115, 600/121, 600/125, 600/310, 600/476-478
• US Class Current: 607/88
• CPC Class Codes: A61B 1/00142 with means for preventing contamination, e.g. by using a sanitary sheath
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence

Abstract

A sheath for use with an interventional device for tissue spectroscopy within a body includes a substantially cylindrical, flexible body having an open proximal end and a closed distal end. The flexible body securely receives interventional device via an interference fit. At least the distal end of the flexible body is formed of a material substantially transmissive of at least one of ultraviolet or visible light. For example, the material can be a polymeric materials such as polyurethane, polyethylene or polystyrene. The sheath can be disposable.

Claims

1. A removable sheath for providing repeated use of an interventional device for tissue spectroscopy in a mammalian body orifice having a contour, the sheath comprising:

a flexible body having an open proximal end and a closed distal end, said flexible body being sized and shaped to receive the interventional device and to be removed from the device, said flexible body being conformable to the contour of the orifice, the distal end of the flexible body comprising a window that is substantially transmissive of an ultraviolet light;

a fluid chamber located at the distal end of the flexible body; and

a channel extending from the proximal end to the distal end of the flexible body for providing fluid to the fluid chamber, wherein the fluid chamber receives a fluid through the channel to facilitate optical contact between the sheath and a tissue under examination.

2. The sheath of claim 1 wherein said window is more transmissive of ultraviolet light than the rest of the flexible body.

3. The sheath of claim 1 wherein the window comprises quartz.

4. The sheath of claim 1 wherein the flexible body is between about 0.003 inch and about 0.010 inch thick.

5. The sheath of claim 1 wherein the flexible body is sized and shaped to securely receive the interventional device via an interference fit.

6. The sheath of claim 1 wherein the flexible body selectively filters light emitted from the tissue at predetermined wavelengths.

7. The sheath of claim 1 wherein the flexible body is formed of a polymeric material.

8. The sheath of claim 7 wherein the flexible body is formed of at least one of polyurethane, polyethylene or polystyrene.

9. The sheath of claim 1 wherein at least the distal end of the flexible body is substantially transmissive of visible light.

10. The sheath of claim 1 wherein the flexible body is substantially cylindrical.

11. The sheath of claim 1 wherein the sheath is disposable.

12. The sheath of claim 6 wherein the flexible body filters light at wavelengths below about 280 nm and above about 500 nm.

13. The sheath of claim 1 wherein the intervention device is selected from the group consisting of a catheter, an endoscope, and an introducer.

14. A device for tissue spectroscopy comprising:

a probe insertable in an orifice of a mammalian body, the probe having a distal end and a proximal end and comprising a tissue spectroscopy apparatus positioned near the distal end, the tissue spectroscopy apparatus comprising a light source for illuminating a tissue under examination with an ultraviolet light, a light detector for detecting an optical property of the illuminated tissue, and a power source; and

a removable sheath for encapsulating said probe, said sheath comprising a flexible body having an open proximal end for receiving the probe and a closed distal end, a fluid chamber located at the distal end of the flexible body, and a channel extending from the proximal end to the distal end of the flexible body for providing fluid to the fluid chamber for optimizing optical contact between the device and the tissue under examination, wherein at least the distal end of the flexible body is substantially transmissive of the ultraviolet light.

15. The device of claim 14 further comprising a window disposed on the distal end of the flexible body.

16. The device of claim 14 wherein the flexible body is between about 0.003 inch and about 0.010 inch thick.

17. The device of claim 14 wherein the flexible body selectively filters light emitted from the tissue at predetermined wavelengths.

18. The device of claim 17 wherein the flexible body filters light at wavelengths below about 280 nm and above about 500 nm.

19. The device of claim 14 wherein the flexible body is formed of a polymeric material.

20. The device of claim 19 wherein the flexible body is formed of at least one of polyurethane, polyethylene or polystyrene.

21. The device of claim 14 wherein the sheath is disposable.

22. A method of conducting tissue spectroscopy, said method comprising the steps of:

providing a device having a distal end and a proximal end and comprising a tissue spectroscopy apparatus positioned near the distal end, said tissue spectroscopy apparatus comprising a light source for illuminating a tissue under examination with an ultraviolet light;

encapsulating said device in a removable sheath, said sheath having (i) an open proximal end and a closed distal end, the distal end of the sheath comprising a window that is substantially transmissive of said ultraviolet light, (ii) a fluid chamber, and (iii) a channel extending from the proximal end of the sheath to said fluid chamber;

inserting the encapsulated device into a mammalian body orifice having a contour, until the distal end of the device is adjacent the tissue;

manipulating the encapsulated device to conform to the contour of the orifice; and

injecting a fluid into said fluid chamber through said channel to facilitate optical contact between the encapsulated device and the tissue.

23. The method of claim 22, further comprising the steps of:

removing the encapsulated device from the orifice;

removing the sheath from the device; and

reusing the device in tissue spectroscopy.

24. The method of claim 22, wherein said window is more transmissive of the ultraviolet light than the rest of the sheath.

25. The method of claim 22 wherein the window comprises quartz.

26. The method of claim 22 wherein the sheath is between about 0.003 inch and about 0.010 inch thick.

27. The method of claim 22 wherein the sheath selectively filters light emitted from the tissue at predetermined wavelengths.

28. The method of claim 22 wherein the sheath filters light at wavelengths below about 280 nm and above about 500 nm.

29. The method of claim 22 wherein the sheath is formed of a polymeric material.

30. A method of conducing tissue spectroscopy, said method comprising the steps of:

providing a device having a distal end and a proximal end and comprising a tissue spectroscopy apparatus positioned near the distal end, the tissue spectroscopy apparatus comprising a light source for illuminating tissue under examination with an ultraviolet light and a light detector for detecting an optical property of the illuminated tissue;

encapsulating said device in a removable sheath, said sheath having an open proximal end and a closed distal end, the distal end of the sheath comprising a window that is substantially transmissive of said ultraviolet light, and a fluid chamber, the sheath further comprising a channel extending from the proximal end of the sheath to said fluid chamber;

inserting the encapsulated device into a mammalian body orifice having a contour, until the distal end of the device is adjacent the tissue;

manipulating the encapsulated device to conform to the contour of the orifice; and

injecting a fluid into said fluid chamber through said channel to facilitate optical contact between the encapsulated device and the tissue.

31. The method of claim 30, further comprising the steps of:

removing the encapsulated device from the orifice;

removing the sheath from the device; and

reusing the device in tissue spectroscopy.

32. The method of claim 30, wherein the tissue spectroscopy apparatus further comprises a power source.

33. The method of claim 30, wherein said window is more transmissive of the ultraviolet light than the rest of the sheath.

34. The method of claim 30 wherein the window comprises quartz.

35. The method of claim 30 wherein the sheath is between about 0.003 inch and about 0.010 inch thick.

36. The method of claim 30 wherein the sheath selectively filters light emitted from the tissue at predetermined wavelengths.

37. The method of claim 36 wherein the sheath filters light at wavelengths below about 280 nm and above about 500 nm.

38. The method of claim 30 wherein the sheath is formed of a polymeric material.