Multi-phasic microphotodetector retinal implant with variable voltage and current capability

• US 6,389,317 B1
• Filed: 03/31/2000
• Issued: 05/14/2002
• Est. Priority Date: 03/31/2000
• Status: Expired due to Term

• Current Assignee: Pixium Vision SA
• Original Assignee: Optobionics Corporation
• Inventors: Chow, Alan Y., Chow, Vincent
• Primary Examiner(s): Schaetzle, Kennedy
• Assistant Examiner(s): DROESCH, KRISTEN L
• Application Number:
  US09/539,399
• Time in Patent Office: 774 Days
• Field of Search: 607/1-2, 607/53-54, 607/116, 607/148, 623/4.1, 623/6.63
• US Class Current: 607/54
• CPC Class Codes: A61F 9/08 Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

A visible and infrared light powered retinal implant is disclosed that is implanted into the subretinal space for electrically inducing formed vision in the eye. The retinal implant includes a stacked microphotodetector arrangement having an image sensing pixel layer and a voltage and current gain adjustment layer for providing variable voltage and current gain to the implant so as to obtain better low light implant performance than the prior art, and to compensate for high retinal stimulation thresholds present in some retinal diseases. A first light filter is positioned on one of the microphotodetectors in each of the image sensing pixels of the implant, and a second light filter is positioned on the other of the microphotodetectors in the image sensing pixel of the implant, each of the microphotodetectors of the pixel to respond to a different wavelength of light to produce a sensation of darkness utilizing the first wavelength, and a sensation of light using the second wavelength, and a third light filter is positioned on a portion of the voltage and current gain adjustment layer that is exposed to light, to allow adjustment of the implant voltage and current gain of the device by use of a third wavelength of light.

Claims

1. A retinal implant for electrically inducing formed vision in an eye, the retinal implant comprising:

a plurality of first layer microphotodetector pairs for receiving light incident on the eye, each first layer microphotodetector pair comprising;

a PiN microphotodetector and a NiP microphotodetector, wherein the P-portion of the PiN microphotodetector and the N-portion of the NiP microphotodetector are aligned on a first end, and the N-portion of the piN microphotodetector and the P-portion of the NiP microphotodetector are aligned on a second end; and

a common electrode in electrical communication between the P-portion and the N-portion of the first end of the microphotodetector pair;

a gain adjustment layer having a first side and a second side, the first side having a first portion electrically connected in series with the second end of at least a portion of the plurality of first layer microphotodetector pairs, and a second portion integrally formed with the first portion and extending away from the first portion, wherein the second portion is oriented to receive light incident on the eye; and

,

a common electrode plane in electrical contact with the second side of the gain adjustment layer, whereby the common electrode plane serves as an electrical ground for the retinal implant.

2. The retinal implant of claim 1, wherein the gain adjustment layer comprises at least one PiN photodetector having a P-portion and an N-portion, the P-portion of the at least one PiN photodetector of the gain adjustment layer in electrical communication with the N-portion of at least one of the PiN microphotodetectors of the first layer microphotodetector pairs.

3. The retinal implant of claim 1, wherein the gain adjustment layer comprises at least one NiP photodetector having a N-portion and a P-portion, the N-portion of the at least one NiP photodetector in electrical communication with the P-portion of at least one of the first layer NiP microphotodetectors of the first layer microphotodetector pairs.

4. The retinal implant of claim 1, wherein the gain adjustment layer comprises a plurality of parallel PiN and NiP photodetector strips.

5. The retinal implant of claim 4, wherein the plurality of first layer microphotodetector pairs further comprises columns of microphotodetector pairs, wherein the N-portion of the PiN microphotodetector in a pair is in electrical communication with a P-portion of a PiN photodetector strip in the gain layer and the P-portion of the NiP microphotodetector in the pair is in electrical communication with a N-portion of a NiP photodetector strip in the gain layer.

6. The retinal implant of claim 4, wherein the plurality of parallel PiN and NiP photodetector strips are positioned in an alternating pattern.

7. The retinal implant of claim 1, wherein the first end of the second portion of the gain adjustment layer is coated with a first filter material configured to pass a first predetermined portion of wavelengths of visible and infrared light selected from a range of 400 nanometers to 2 microns.

8. The retinal implant of claim 7, wherein the first predetermined portion of wavelengths is selected from a range of 800 nanometers to 2 microns.

9. The retinal implant of claim 7, wherein each of the plurality of first layer microphotodetector pairs further comprises a second filter material positioned over the N-portion on the first end of at least one of the plurality of microphotodetector pairs.

10. The retinal implant of claim 9, wherein the second filter material is configured to pass a second predetermined portion of wavelengths of visible or infrared light in a range of 400 nanometers to 2 microns.

11. The retinal implant of claim 10 wherein the second predetermined portion of wavelengths is different than the first predetermined portion of wavelengths.

12. The retinal implant of claim 11 wherein the second predetermined portion of wavelengths is selected from a range of 650 nanometers to 800 nanometers.

13. The retinal implant according to any of claims 7-11 wherein each of the plurality of first layer microphotodetector pairs further comprises a third filter material positioned over the P-portion on the first end of at least one of the plurality of microphotodetector pairs.

14. The retinal implant of claim 13, wherein the third filter material is configured to pass a third predetermined portion of wavelengths selected from a range of 400 nanometers to 2 microns.

15. The retinal implant of claim 14 wherein the third predetermined portion of wavelengths is different than the first and second predetermined portions of wavelengths.

16. The retinal implant of claim 15, wherein the third predetermined portion of wavelengths is selected from a range of 400 nanometers to 650 nanometers.

17. A retinal implant for electrically inducing formed vision in an eye, the retinal implant comprising:

a plurality of microphotodetector pixels, each of the plurality of microphotodetector pixels spaced apart from any adjacent microphotodetector pixels and each of the pixels embedded in a lattice-like mesh, wherein each of the microphotodetector pixels comprises;

at least one first layer microphotodetector pair for receiving light incident on the eye, each microphotodetector pair comprising;

a PiN microphotodetector and a NiP microphotodetector, wherein the P-portion of the PiN microphotodetector and the N-portion of the NiP microphotodetector are aligned on a first end, and the N-portion of the PiN microphotodetector and the P-portion of the NiP microphotodetector are aligned on a second end; and

a common electrode in electrical communication between the P-portion and the N-portion of the first end of the microphotodetector pair; and

a gain adjustment layer having a first side and a second side, the first side having a first portion electrically connected in series with the second end of at least a portion of the plurality of first layer microphotodetector pairs, and a second portion integrally formed with the first portion and extending away from the first portion, wherein the second portion is oriented to receive light incident on the eye.

18. The retinal implant of claim 17 wherein the lattice-like mesh comprises a common ground electrode electrically connected to all of the plurality of microphotodetector pixels.

19. A retinal implant for electrically inducing formed vision in an eye, the retinal implant comprising:

a first layer comprising a plurality of microphotodetector pairs, each microphotodetector pair comprising;

a PiN microphotodetector and a NiP microphotodetector, wherein the P-portion of the PiN microphotodetector and the N-portion of the NiP microphotodetector are aligned on a first end, and the N-portion of the PiN microphotodetector and the P-portion of the NiP microphotodetector are aligned on a second end; and

a common electrode in electrical communication between the P-portion and the N-portion of the first end of the microphotodetector pair;

a first common electrode strip in electrical contact with the N-portions of the second end of each of the plurality of PiN microphotodetectors of the microphotodetector pairs;

a second common electrode strip in electrical contact with the P-portions of the second end of each of the plurality of NiP microphotodetectors of the PiN/NiP microphotodetector pairs;

a second layer photodetector gain adjustment layer comprising a first end and a second end, the first end comprising a first portion electrically connected in series with the common electrode strips of both the N-portion and P-portion of the second end of the first layer of microphotodetector pairs, and a second portion integrally formed with the first portion extending away from the first portion and oriented to receive light incident on the eye; and

a common electrode plane for the second layer photodetector gain adjustment layer in direct electrical contact with the second end of both the first portion and the second portion of the photodetector, gain adjustment layer, the common electrode plane serving as the electrical ground of the retinal implant.

20. An adjustable voltage and current gain microphotodetector retinal implant for electrically inducing formed vision in an eye, the retinal implant comprising:

a first microphotodetector layer comprising at least one PiN microphotodetector, the first microphotodetector layer having a bandpass filter configured to pass visible light, and

a voltage and current gain adjustment layer comprising at least one PiN photodetector, the voltage and current gain adjustment layer having a first side comprising a first portion electrically connected in series with, and covered by, a portion of the at least one PiN microphotodetector of the first microphotodetector layer, and a second portion, not covered by the first microphotodetector layer, comprising an infrared bandpass filter.

21. The retinal implant of claim 20, further comprising at least one upper electrode positioned on the first microphotodetector layer, and at least one lower electrode positioned on the voltage and current gain adjustment layer, the upper and lower electrodes comprising sputtered iridium/iridium oxide.

22. An adjustable voltage and current gain microphotodetector retinal implant for electrically inducing formed vision in an eye, the retinal implant comprising:

a first microphotodetector layer comprising at least one PiN microphotodetector, the first microphotodetector layer comprising an amorphous silicon material, wherein the first microphotodetector layer is oriented to receive light incident on the eye; and

a gain adjustment layer comprising at least on PiN photodetector, the PiN photodetector having a first side electrically connected in series with, and covered by, the at least one PiN microphotodetector of the first microphotodetector layer.

23. The retinal implant of claim 22, wherein the first microphotodetector layer is configured to pass a portion of the light incident on the eye and the first side of the at least one PiN photodetector of the gain adjustment layer receives the portion of light through the first microphotodetector layer.