Aerosol inhaler

• US 6,390,088 B1
• Filed: 01/20/2000
• Issued: 05/21/2002
• Est. Priority Date: 12/13/1993
• Status: Expired due to Fees

• Current Assignee: Boehringer Ingelheim Promeco SA de CV (C.H. Boehringer Sohn AG & Co. KG)
• Original Assignee: Boehringer Ingelheim Promeco SA de CV (C.H. Boehringer Sohn AG & Co. KG)
• Inventors: Sprenger, Harald, Nöhl, Klaus
• Primary Examiner(s): Weiss, John G.
• Assistant Examiner(s): PATEL, MITAL B
• Application Number:
  US09/488,499
• Time in Patent Office: 852 Days
• Field of Search: 128/200.14, 128/200.23, 128/204.23, 128/205.23, 128/203.12, 128/200.24
• US Class Current: 128/200.23
• CPC Class Codes: A61M 15/0083 Timers
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2205/13 with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/44 making noise when used incorrectly
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/60 with identification means
• CPC Class Codes: A61M 2205/6072 Bar codes

Abstract

In an aerosol inhaler it is proposed that a thermal sensor 5 be arranged in the region of the atomization nozzle 4, which sensor, following the actuation of an actuating element and the triggering of an inhalation process, undergoes cooling as a result of the expansion of the propellant which then occurs. The actuation and cooling are electronically detected in an electronic module 3. Technical and therapeutic data can be derived from the signal, which data are communicated to the user via the display unit and/or alarm devices and influence the therapy in the desired manner. See FIG. 1.

Claims

1. An improved inhaler for the administration by inhalation of an aerosol consisting of a medicament and a propellant, of the type comprising:

a) a supply container having propellant and medicament therein;

b) a nozzle for atomizing propellant and medicament conveyed thereto, to form an aerosol therefrom, having an opening from which the aerosol so formed is expelled;

c) means for conveying propellant from the supply container to the nozzle;

d) an actuating element for causing the conveyance of propellant and medicament from the supply container to the nozzle, upon actuation by a user of the inhaler; and

,

e) a mouthpiece having a channel, through which the aerosol formed by the nozzle is expelled from the inhaler, so that it may be inhaled;

wherein the improvement comprises an electronic means for sensing and reporting whether aerosol has been expelled from the inhaler upon actuation by the user, said electronic means comprising;

f) a thermal sensor, located in the vicinity of the nozzle opening, which produces an electrical signal that varies in response to the temperature in the vicinity of the nozzle opening, including the decrease in temperature caused by any expulsion of aerosol from the nozzle opening;

g) an actuation-recognition device for producing an electrical signal upon actuation of the actuating element;

h) an evaluating electronic unit, connected to both the thermal sensor and the actuation recognition device, which uses the signals from the thermal sensor and the actuation recognition device to evaluate the extent to which there has been a decrease in temperature in the vicinity of the nozzle opening which coincides with actuation of the actuating element, and which thereby makes a determination whether aerosol has been expelled from the inhaler upon actuation by the user; and

,

i) an electronic display, by means of which the determination of the evaluating electronic unit is reported.

2. An inhaler according to claim 1, further comprising means for generating an audible warning signal when no expulsion of aerosol has taken place.

3. An inhaler according to claim 1 wherein the evaluating electronic unit further deduces the amount of aerosol expelled with each actuation by integrating the temperature decrease caused by the aerosol expulsion caused by each actuation over the period of the expulsion.

4. An inhaler according to claim 1, wherein the evaluating electronic unit comprises a memory for storing the results of determinations made by the unit.

5. An inhaler according to claim 4, wherein the evaluating electronic unit comprises an interface whereby the results of determinations stored in the memory of the unit can be transferred to an external computer.

6. An improved inhaler for the administration by inhalation of an aerosol consisting of a medicament and a propellant, of the type comprising:

a) a supply container having propellant and medicament therein;

b) a nozzle for atomizing propellant and medicament conveyed thereto, to form an aerosol therefrom, having an opening from which the aerosol so formed is expelled;

c) means for conveying propellant from the supply container to the nozzle;

d) an actuating element for causing the conveyance of propellant and medicament from the supply container to the nozzle, upon actuation by a user of the inhaler; and

,

e) a mouthpiece having a channel, through which the aerosol formed by the nozzle is expelled from the inhaler, so that it may be inhaled;

wherein the improvement comprises an electronic means for sensing and reporting whether aerosol has been expelled from the inhaler upon actuation by the user, said electronic means comprising;

f) a thermal sensor, located in the vicinity of the nozzle opening, which produces an electrical signal that varies in response to the temperature in the vicinity of the nozzle opening, including the decrease in temperature caused by any expulsion of aerosol from the nozzle opening;

g) an actuation-recognition device for producing an electrical signal upon actuation of the actuating element;

h) an evaluating electronic unit, connected to both the thermal sensor and the actuation recognition device, which uses the signals from the thermal sensor and the actuation recognition device to evaluate the extent to which there has been a decrease in temperature in the vicinity of the nozzle opening which coincides with actuation of the actuating element, and which thereby makes a determination whether aerosol has been expelled from the inhaler upon actuation by the user, and which evaluating electronic unit further makes a determination of the amount of aerosol expelled with each actuation by integrating the temperature decrease caused by the aerosol expulsion caused by each actuation over the period of the expulsion; and

,

i) an electronic display, by means of which the determinations of the evaluating electronic unit are reported.