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Method for measuring the cutaneous electrical resistance of a patient subjected to transdermal administration of medicine

  • US 6,391,015 B1
  • Filed: 05/17/1999
  • Issued: 05/21/2002
  • Est. Priority Date: 11/19/1996
  • Status: Expired due to Fees
First Claim
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1. A method for measuring the cutaneous electrical resistance of a patient undergoing transdermal administration of medication assisted by an iontophoresis current, wherein the current is applied across a surface of a patient using an iontophoretic device, the iontophoretic device comprising a reservoir having a medicament, a first electrode and a second electrode, the method comprising the steps of:

  • temporarily adjusting the current from a treatment current density to a predetermined current density, wherein the predetermined current density is within a range of values for which the current density and the voltage have a direct relationship;

    measuring the voltage drop across the surface of a patient between the first electrode and the second electrode; and

    calculating the resistance of the surface of a patient at a region between the first and second electrodes from the measured voltage value and the predetermined current density.

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