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Identification of molecular sequence signatures and methods involving the same

  • US 6,391,550 B1
  • Filed: 05/27/1999
  • Issued: 05/21/2002
  • Est. Priority Date: 09/19/1996
  • Status: Expired due to Term
First Claim
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1. A method for determining whether a target molecule has a sequence from a member of a gene family comprising:

  • providing a polynucleotide array comprising, for each of at least two different members of the gene family, a set of polynucleotide probes that define a reference nucleotide sequence from the member of the gene family;

    generating hybridization data by performing a hybridization reaction between the target nucleic acid molecule and the probes in the sets and detecting hybridization between the target nucleic acid molecule and each of the probes in the sets; and

    processing the hybridization data to determine whether the target nucleic acid has the reference sequence from one of the members of the gene family.

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