Method and apparatus for drug infusion

• US 6,394,981 B2
• Filed: 10/11/1999
• Issued: 05/28/2002
• Est. Priority Date: 04/30/1996
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Heruth, Kenneth T.
• Primary Examiner(s): KENNEDY, SHARON E
• Application Number:
  US09/416,151
• Publication Number:
  US 20010031947A1
• Time in Patent Office: 960 Days
• Field of Search: 604/131,132,141,143,149,214,218,315,316,88,93,140,146,150-155,891.1
• US Class Current: 604/140
• CPC Class Codes: A61M 2005/14506 mechanically driven, e.g. spring or clockwork
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

The present disclosure describes a system wherein a drug or other fluid to be delivered to a specific desired location within the body is stored in a reservoir that is directly displaced by a force to infuse the drug from the device into the patient. Several specific methods are used to displace the reservoir, including, generally, hydraulic displacement, mechanical screw-type displacement, and spring force displacement of the fluid reservoir.

Claims

1. A method of infusing a drug to a specific desired location within a patient'"'"'s body, comprising:

implanting a first reservoir, a second reservoir situated directly adjacent the first reservoir, a third reservoir in fluid communication with the second reservoir, and a pump operatively connected between the second and third reservoirs within the patient'"'"'s body, the second reservoir containing a working fluid;

providing a supply of the drug in fluid communication with the first reservoir;

operating the pump to transfer working fluid from the second reservoir to the third reservoir to increase the volume of the first reservoir and draw at least a portion of the provided supply of the drug into the first reservoir; and

operating the pump to transfer working fluid from the third reservoir to the second reservoir to decrease the volume of the first reservoir and deliver at least a portion of the drug from the first reservoir and through an established fluid passageway extending between the first reservoir and the specific desired location within the patient'"'"'s body.

2. A method of drawing a drug fluid into a drug infusion device implanted in the body, comprising:

implanting a first reservoir, a second reservoir situated directly adjacent the first fluid reservoir, a third reservoir in fluid communication with the second reservoir, and a pump operatively connected between the second and third reservoirs within the body, the second reservoir containing a working fluid;

providing a supply of the drug fluid in fluid communication with the first reservoir of the infusion device; and

operating the pump to transfer working fluid from the second reservoir to the third reservoir thus increasing the volume of the first reservoir to draw the drug fluid into the first reservoir.

3. The method of claim 2, wherein providing the supply of the drug fluid includes inserting a delivery needle into the first reservoir.

4. The method of claim 2, wherein the first reservoir includes a bellows, and wherein operating the pump to transfer working fluid from the second reservoir to the third reservoir includes pumping the working fluid from the second reservoir to the third reservoir to expand the bellows, thus increasing the volume of the first reservoir.

5. The method of claim 2, wherein the drug infusion device includes a sliding piston situated between the first reservoir and the second reservoir, and wherein operating the pump to transfer working fluid from the second reservoir to the third reservoir includes pumping the working fluid from the second reservoir to the third reservoir to move the sliding piston in a first direction, thus increasing the volume of the first reservoir.

6. A method of infusing a drug fluid into a body from a drug infusion device implanted in the body, the method comprising:

implanting a first reservoir, a second reservoir situated directly adjacent the first fluid reservoir, a third reservoir in fluid communication with the second reservoir, and a pump operatively connected between the second and third reservoirs within the body, the third reservoir containing a working fluid;

providing a supply of the drug fluid into the first reservoir; and

operating the pump to transfer working fluid from the third reservoir to the second reservoir to reduce the volume of the first reservoir thus delivering the drug fluid from the first reservoir to the body.

7. The method of claim 6, wherein the first reservoir includes a bellows, and wherein operating the pump to transfer the working fluid includes pumping the working fluid from the third reservoir to the second reservoir to collapse the bellows, thus reducing the volume of the first reservoir.

8. The method of claim 7, further comprising:

providing the supply of the drug fluid external to the body in fluid communication with the first reservoir; and

operating the pump to transfer working fluid from the second reservoir to the third reservoir to expand the bellows, thus increasing the volume of the first reservoir to draw the drug fluid into the first reservoir.

9. The method of claim 6, wherein the drug infusion device includes a sliding piston situated between the first reservoir and the second reservoir, and wherein operating the pump to transfer the working fluid includes pumping the working fluid from the third reservoir to the second reservoir to move the sliding piston in a first direction, thus reducing the volume of the first reservoir.

10. The method of claim 9, further comprising:

providing the supply of the drug fluid external to the body in fluid communication with the first reservoir; and

operating the pump to transfer working fluid from the second reservoir to the third reservoir to move the sliding piston in a second direction, thus increasing the volume of the first reservoir to draw the drug fluid into the first reservoir.