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Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same

  • US 6,397,100 B2
  • Filed: 10/01/2001
  • Issued: 05/28/2002
  • Est. Priority Date: 03/29/1999
  • Status: Expired due to Term
First Claim
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1. Apparatus for determining if an axis shift has occurred in an electrocardiogram signal so as to provide a better data set for evaluating a physiologic condition based on said cardiac electrogram signal, wherein said apparatus receives said electrocardiogram signal through a plurality of electrical leads connected to provide said cardiac electrogram signal from a plurality of electrical vectors, said apparatus comprising:

  • an electrogram reading device connected to said plurality of electrodes for sensing the amplitude variation in the electrical signal of a heart for each electrical vector, a sampling and digitizing circuit for digitizing samples of said cardiac electrical amplitude signal and to provide an output stream of digitized sample point values representative of said samples, a V-event detection circuit for generating a V-event signal at its output indicating that a ventricular event has occurred, a buffer circuit for holding a set of point values that are temporally related to a time in a cardiac cycle when said V-event signal is output from said V-event detection circuit, a fiducial point determining circuit means for reading the set of point values from said buffer circuit for determining which of said point values is a fiducial point related to said V-event signal, a subset determining and selecting circuit for determining based at least in part on a temporal relative location of said determined fiducial point to said set of point values which subset of said set of point values to select and selecting them, a parameterizing processor circuit for producing a set of parameter values related to said set of point values selected and determined by said subset determining circuit wherein at least some of the parameters produced are evaluatable by a physiologic condition signal processor circuit, a physiologic condition signal circuit means for calculating a physiologic condition signal variable value, an expected range value recalculating circuit for employing said set of parameter values and said pre-calculated expected ranges to produce new pre-calculated expected ranges to produce new pre-calculated expected range values for a next set of parameter values to be compared with a comparison circuit for comparing said pre-calculated expected ranges with each parameter value from said set of parameter values to determine if it is within its expected range and producing a validity value and as output and for setting an axis shift flag value as an additional output if said parameter values exhibit axis shift characteristics, a cardiac cycle validity determining circuit which receives said validity value and said axis shift flag values for determining if said validity value is sufficient to employ said set of parameter values for determining a physiologic condition and for recalculating said set of expected ranges by said recalculating circuit and for providing a cycle validity flag value signal representing the determination of sufficiency of cycle validity for a cardiac cycle, an evaluation circuit for evaluating said physiologic condition based on running changes in said current physiologic condition variable value from those cycles determined to be sufficiently valid.

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