Radiation dosimetry system

• US 6,398,710 B1
• Filed: 01/06/2000
• Issued: 06/04/2002
• Est. Priority Date: 01/06/1999
• Status: Expired due to Fees

• Current Assignee: Ball Semiconductor, Inc.
• Original Assignee: Ball Semiconductor, Inc.
• Inventors: Ahn, Samuel S., Gaffney, F. Andrew, Ishikawa, Akira, Ahn, Suzanne I., Takeda, Nabuo, Hays, Steven R.
• Primary Examiner(s): Lacyk, John P.
• Assistant Examiner(s): Veniaminov, Nikita R.
• Application Number:
  US09/478,591
• Time in Patent Office: 880 Days
• Field of Search: 600/317, 600/300-436, 600/1-3, 601/3, 250/484.5, 345/349, 424/1.49, 378/65
• US Class Current: 600/3
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: G01T 1/026 Semiconductor dose-rate meters
• CPC Class Codes: G01T 1/161 Applications in the field of nuclear medicine, e.g. in vivo counting apparatus for radiation diagnosis A61B6/00

Abstract

A radiation dosimetry system (110) using miniature implanted transponder balls. A patient having a tumor that is the target of the radiation treatment lies in a treatment area with the tumor positioned beneath a target (112) used for alignment purposes. The system (110) is controlled and monitored by a CPU (114) which receives instructions from a radiologist operating a control panel (116), and displays control parameters, data and graphics to the radiologist on a display (118). The CPU (114) controls an RF system operating through a broad-band antenna (120) and directed at the target area (112). The CPU (114) controls operation of a radiation source (122), which may be a conventional linear accelerator, for directing radiation at the target area (112). The radiation source (122) includes a collimator (124) or similar apparatus for shaping a radiation beam for accurate application to the target area (112). A pair of RF receivers (126) and (128) are positioned such that they are spaced apart and opposite from the CPU antenna (120) with respective antennas (130) and (132) directed at the target area (112). Communication connections (133a), (133b), (133c), (133d) and (133e) interconnect the various elements of the system (110).

Claims

1. A system for detecting a dosage of radiation received by a tumor during radiation treatment, comprising:

a radiation source that is adapted to be directed at the tumor;

a central processing unit connected to the radiation source for monitoring and controlling the radiation treatment; and

one or more dosimetry transponders adapted to be injected into the tumor, each said dosimetry transponder having,

a memory in which a unique identification code is stored for distinguishing each transponder from the other transponders,

a communication circuit for communicating power and control signals between said transponder and said central processing unit, and

one or more detectors for detecting radiation and converting the detected radiation to a data signal.

2. The system of claim 1, wherein each said dosimetry transponder comprises a spherical-shaped semiconductor substrate on which circuitry is formed.

3. The system of claim 1, further comprising a catheter delivery system that is adapted for injecting a slurry of multiple said dosimetry transponders into the tumor via a feeding blood vessel.

4. The system of claim 1, further comprising first and second receivers located in a spaced relationship to each other and connected to said central processing unit for detecting the precise position of each of the dosimetry transponders are adapted to be injected into the tumor to permit three-dimensional mapping of locations of said transponders for display during the radiation treatment.

5. The system of claim 1, wherein said central processing unit connects to a display for presenting dosimetry data.

6. The system of claim 1, wherein said one or more transponders comprise radiation-sensitive diodes for detecting radiation interspersed among one or more communication coils for communicating power and data signals to said one or more transponders.

7. A method for detecting a dosage of radiation received by a tumor during radiation treatment, comprising the steps of:

directing a radiation source at the tumor;

connecting a central processing unit to the radiation source for monitoring and controlling the radiation treatment; and

injecting one or more dosimetry transponders into the tumor, each dosimetry transponder having,

a memory in which a unique identification code is stored for distinguishing each transponder from the other transponders,

a communication circuit for communicating power and control signals between the transponder and the central processing unit, and

one or more detectors for detecting radiation and converting the detected radiation to a data signal.

8. The method of claim 7, wherein each the dosimetry transponder in the step of injecting comprises a spherical-shaped semiconductor substrate on which circuitry is formed.

9. The method of claim 7, further comprising a catheter delivery system in the step of injecting for injecting a slurry of multiple the dosimetry transponders into the tumor via a feeding blood vessel.

10. The method of claim 7, further comprising first and second receivers in the step of connecting located in a space relationship to each other and connected to the central processing unit for detecting the precise position of each the dosimetry transponder injected into the tumor to permit three-dimensional mapping of locations of the transponders for display during the radiation treatment.

11. The method of claim 7, wherein the central processing unit in the step of connecting connects to a display for presenting dosimetry data.

12. The method of claim 7, wherein the one or more transponders in the step of injecting comprise radiation-sensitive diodes for detecting radiation interspersed among one or more communication coils for communicating power and data signals to the one or more transponders.

13. A system for detecting a dosage of radiation received by a tumor during radiation treatment, comprising:

a radiation source that is adapted to be directed at the tumor;

a central processing unit connected to the radiation source for monitoring and controlling the radiation treatment; and

one or more dosimetry transponders are adapted to be injected into the tumor, each said dosimetry transponder having,

a communication circuit for communicating power and control signals between said transponder and said central processing unit, and

one or more detectors for detecting radiation and converting the detected radiation to a data signal,

wherein the system further comprises first and second receivers located in a spaced relationship to each other and connected to said central processing unit for detecting the precise position of each of the dosimetry transponder adapted to be injected into the tumor to permit three-dimensional mapping of locations of said transponders for display during the radiation treatment.

14. The system of claim 13, wherein each said dosimetry transponder comprises a spherical-shaped semiconductor substrate on which circuitry is formed.

15. The system of claim 13, further comprising a catheter delivery system that is adapted for injecting a slurry of multiple said dosimetry transponders into the tumor via a feeding blood vessel.

16. The system of claim 13, wherein each said dosimetry transponder includes a memory in which a unique identification code is stored for distinguishing one said transponder from another said transponder.

17. The system of claim 13, wherein said central processing unit connects to a display for presenting dosimetry data.

18. The system of claim 13, wherein said one or more transponders comprise radiation-sensitive diodes for detecting radiation interspersed among one or more communication coils for communicating power and data signals to said one or more transponders.

19. A method for detecting a dosage of radiation received by a tumor during radiation treatment, comprising the steps of:

directing a radiation source at the tumor;

connecting a central processing unit and first and second receivers to the radiation source for monitoring and controlling the radiation treatment, the receivers being located in a spaced relationship to each other, the radiation source and the tumor for detecting the precise position of each of the dosimetry transponders injected into the tumor to permit three-dimensional mapping of locations of the transponders for display during the radiation treatment; and

injecting one or more dosimetry transponders into the tumor, each dosimetry transponder having,

a communication circuit for communicating power and control signals between the transponder and the central processing unit, and

one or more detectors for detecting radiation and converting the detected radiation to a data signal.

20. The method of claim 19, wherein each the dosimetry transponder in the step of injecting comprises a spherical-shaped semiconductor substrate on which circuitry is formed.

21. The method of claim 19, further comprising a catheter delivery system in the step of injecting for injecting a slurry of multiple dosimetry transponders into the tumor via a feeding blood vessel.

22. The method of claim 19, wherein each of the dosimetry transponders in the step of injecting includes a memory in which a unique identification code is stored for distinguishing each transponder from the other transponders.

23. The method of claim 19, wherein the central processing unit in the step of connecting connects to a display for presenting dosimetry data.

24. The method of claim 19, wherein the one or more transponders in the step of injecting comprise radiation-sensitive diodes for detecting radiation interspersed among one or more communication coils for communicating power and data signals to the one or more transponders.