Volumetric infusion pump with servo valve control

• US 6,398,760 B1
• Filed: 10/01/1999
• Issued: 06/04/2002
• Est. Priority Date: 10/01/1999
• Status: Expired due to Fees

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Danby, Hal C.
• Primary Examiner(s): Dawson, Glenn K.
• Assistant Examiner(s): MAYNARD, JENNIFER J
• Application Number:
  US09/410,676
• Time in Patent Office: 977 Days
• Field of Search: 604/131, 604/132, 604/133, 604/134, 604/135, 604/140, 604/141, 604/142, 604/143, 604/144, 604/67, 417/474-479
• US Class Current: 604/132
• CPC Class Codes: A61M 5/1483 using flexible bags externally pressurised by fluid pressure
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28

Abstract

An infusion pump (10) includes a reservoir (18) containing a therapeutic liquid to be infused. The reservoir (18) includes an outlet (36) for the liquid. A volumetric air pump (24) is operatively associated with the reservoir (18) to pressurize the reservoir and thus drive liquid out the outlet (36). A valve (12) is operatively associated with the outlet (36) and prevents the flow of liquid through the outlet until a select threshold pressure is obtained in the outlet. The valve thereafter maintains an opening in the outlet that keeps the pressure in the reservoir (18) at substantially the select threshold pressure, whereby the volumetric flow rate of liquid through the outlet (36) is proportional to the volumetric flow rate of air from the volumetric air pump (24). The valve (12) varies the opening in the outlet to maintain the select pressure. The outlet preferably consists of a flexible conduit (36) having a select undeformed inner cross-sectional area and the valve (12) variably restricts the flow of liquid through the outlet by pinching a segment of the conduit to vary the inner cross-sectional area of the segment of the conduit. A method of infusing therapeutic liquid to a patient includes providing a reservoir (18) containing a therapeutic liquid, providing a volumetric air pump (24) to pressurize the reservoir to flow liquid out the liquid reservoir through an outlet (36) and maintaining a select pressure in the reservoir so that liquid through the liquid outlet is proportional to the volumetric flow rate of the volumetric air pump.

Claims

1. An infusion pump comprising:

a reservoir containing a therapeutic liquid to be infused, the reservoir having an outlet for the liquid;

a volumetric air pump operatively associated with the reservoir to pressurize the reservoir; and

means for preventing liquid flow through the liquid outlet until a select pressure is obtained in the outlet and thereafter varying an opening in the outlet to maintain the pressure in the reservoir at substantially the select pressure, whereby the volumetric flow rate of liquid through the outlet is proportional to the volumetric flow rate of air from the volumetric air pump.

2. The infusion pump of claim 1 wherein the outlet comprises a flexible conduit and the valve varies the opening in the outlet by pinching a segment of the conduit to vary an inner cross-sectional area of the segment of the conduit.

3. The infusion pump of claim 1 wherein the reservoir comprises a collapsible wall and further comprising an inflatable bladder juxtaposed with the collapsible wall of the reservoir, the volumetric air pump being in fluid communication with the bladder.

4. The infusion pump of claim 3 wherein the volumetric air pump provides gas to the bladder at a first rate until the select pressure is applied to the reservoir and thereafter provides gas to the bladder at a second substantially uniform rate less than the first rate.

5. An infusion pump comprising:

a reservoir containing a therapeutic liquid to be infused, the reservoir having an outlet for the liquid;

a volumetric air pump operatively associated with the reservoir to pressurize the reservoir;

a valve operatively associated with the liquid outlet; and

a mechanical linkage between the reservoir and the valve causing the valve to prevent liquid flow through the liquid outlet until a select pressure is obtained in the reservoir and thereafter causing the valve to vary an opening in the outlet to maintain the pressure in the reservoir at substantially the select pressure.

6. The infusion pump of claim 5 wherein the valve comprises:

a blade and an anvil receiving the liquid outlet therebetween.

7. The infusion pump of claim 6 wherein the mechanical linkage comprises:

an arm having a distal end attached to the blade and a proximal end pivotally attached to a rigid housing, the arm including a pressure pad between the proximal and distal ends in contact with the reservoir.

8. The infusion pump of claim 7 further comprising a spring biasing means operatively associated with the arm.

9. The infusion pump of claim 6 wherein the volumetric air pump pressurizes the reservoir at a first rate until the select pressure sufficient to overcome a biasing force on the blade so as to initially move the blade away from the anvil is applied to the reservoir and thereafter the volumetric air pump pressurizes the reservoir at a second substantially uniform rate less than the first rate.

10. The infusion pump of claim 9 further comprising a detector operatively associated with the arm and the volumetric air pump, the detector detecting the initial movement of the arm and sending a first signal to the volumetric air pump.

11. The infusion pump of claim 10 wherein if the blade moves more than a select distance from the anvil a second signal is sent to the volumetric air pump.

12. The infusion pump of claim 7 wherein the mechanical linkage further comprises means for providing a force biasing the blade toward the anvil.

13. The infusion pump of claim 5 wherein the volumetric air pump pressurizes the reservoir at a first rate until the select pressure is obtained in the reservoir and thereafter the volumetric air pump pressurizes the reservoir at a second substantially uniform rate less than the first rate.

14. A method of infusing therapeutic liquid to a patient comprising:

a) providing a reservoir containing a therapeutic liquid and having a liquid outlet;

b) providing a volumetric air pump in operative association with the reservoir to pressurize the reservoir;

c) maintaining a select pressure in the reservoir by varying an opening in the liquid outlet by means of a valve which is mechanically linked to the reservoir so that a flow of liquid through the liquid outlet is proportional to a volumetric flow rate of the volumetric air pump.

15. The method of claim 14 wherein in step a) the liquid outlet comprises a resilient tube and step c) further comprises applying a pinching force to a segment of the resilient tube and decreasing the pinching force as the pressure in the reservoir increases to increase an effective inner cross-sectional area of the segment of the resilient tube.

16. The method of claim 14 wherein in step a) the liquid outlet comprises a resilient tube and the reservoir is collapsible and step b) further comprises pressurizing the reservoir by providing a bladder juxtaposed with the reservoir in fluid communication with the volumetric air pump, the method further comprising:

d) preventing flow of liquid through the liquid outlet if the pressure in the reservoir is less than the select pressure.

17. The method of claim 16 further comprising:

e) inflating the bladder at a first rate until the select pressure is reached in the reservoir and thereafter inflating the bladder at a second substantially constant rate less than the first rate.