Signal generating oligonucleotide-based biosensor
First Claim
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1. A compound for detecting a target analyte, said compound having the general formula:
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Abstract
The present invention relates to oligonucleotide-based biosensors and a general method for their production and use. Specifically, the invention describes a novel signal-generating ligand complex comprising the combination of two or more aptamers linked together by a polymeric linker and further comprising a signaling system that provides a detectable signal upon binding of the signal-generating ligand complex to its target analyte.
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15 Claims
- 1. A compound for detecting a target analyte, said compound having the general formula:
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4. A device for binding a target analyte, said device comprising
a solid matrix; - and
a signal-generating complex covalently linked to said solid matrix, said signal-generating complex having the general formula;
- View Dependent Claims (5, 6)
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- 7. A compound for detecting a target analyte, said compound having the general formula:
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11. A device for binding a target analyte, said device comprising
a solid matrix; - and
a signal-generating ligand complex covalently linked to said solid matrix, said signal-generating ligand complex having the general formula;
- and
Specification