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Testing multiple fluid samples with multiple biopolymer arrays

  • US 6,399,394 B1
  • Filed: 06/30/1999
  • Issued: 06/04/2002
  • Est. Priority Date: 06/30/1999
  • Status: Expired due to Fees
First Claim
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1. A method of testing multiple fluid samples with multiple biopolymer arrays to detect a binding pattern between the multiple fluid samples and the arrays, comprising:

  • (a) assembling a cover to a one-piece substrate carrying on a first side, multiple arrays each with multiple regions of biopolymers linked to the substrate, such that the cover an the substrate together form a plurality of chambers each containing a biopolymer array and each being accessible through its own port which includes a resilient self-sealing portion;

    (b) introducing the multiple fluid samples into respective chambers through a port of each such that the fluid samples contact respective arrays; and

    (c) observing a binding pattern on the arrays;

    wherein each chamber is accessible through a first and a second port each of which includes a resilient self-sealing portion, the method additionally comprising inserting a first set of conduits through the resilient members of respective first ports, and inserting a second set of conduits through the self-sealing portion of respective second ports, and wherein the multiple fluid samples are introduced into each chamber through the first set of conduits while venting occurs through the second set of conduits.

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